The impact of perfluoroalkyl substances on pregnancy, birth outcomes, and offspring development: a review of data from mouse models† [0.03%]
全氟烷基物质对妊娠、出生结果和后代发育的影响：来自小鼠模型的数据综述†
Zahra Aghaei,Katherine L Steeves,Karl J Jobst et al.
Zahra Aghaei et al.
Per- and polyfluoroalkyl substances (PFASs) such as perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) are persistent in the environment and bioaccumulate in wildlife and humans, potentially causing adverse health effects...
When idiopathic male infertility is rooted in maternal malnutrition during the perinatal period in mice† [0.03%]
当小鼠围产期母体营养不良导致男性原发性不育
Yuki Muranishi,Laurent Parry,Mélanie Vachette-Dit-Martin et al.
Yuki Muranishi et al.
Infertility represents a growing burden worldwide, with one in seven couples presenting difficulties conceiving. Among these, 10-15% of the men have idiopathic infertility that does not correlate with any defect in the classical sperm param...
Jong Geol Lee,Globinna Kim,Seul Gi Park et al.
Jong Geol Lee et al.
The placenta regulates maternal-fetal communication, and its defect leads to significant pregnancy complications. The maternal and embryonic circulations are primitively connected in early placentation, but the function of the placenta duri...
Jessica Y Chotiner,N Adrian Leu,Yang Xu et al.
Jessica Y Chotiner et al.
Stuart B Moss
Stuart B Moss
Dynamics of epigenetic modifiers and environmentally sensitive proteins in a reptile with temperature induced sex reversal† [0.03%]
具有环境敏感蛋白和表观遗传修饰物的爬行动物的性别逆转的动力学研究†
Sarah L Whiteley,Robert D McCuaig,Clare E Holleley et al.
Sarah L Whiteley et al.
The mechanisms by which sex is determined, and how a sexual phenotype is stably maintained during adulthood, have been the focus of vigorous scientific inquiry. Resources common to the biomedical field (automated staining and imaging platfo...
Impact of growth hormone-releasing hormone antagonist on decidual stromal cell growth and apoptosis in vitro† [0.03%]
生长激素释放激素拮抗剂对体外蜕膜基质细胞增殖和凋亡的影响†
Hsien-Ming Wu,Liang-Hsuan Chen,Andrew V Schally et al.
Hsien-Ming Wu et al.
Endometrial stromal cells remodeling is critical during human pregnancy. Growth hormone-releasing hormone and its functional receptor have been shown to be expressed in gynecological cancer cells and eutopic endometrial stromal cells. Recen...
Phthalates and alternative plasticizers differentially affect phenotypic parameters in gonadal somatic and germ cell lines† [0.03%]
酞酸盐及其替代增塑剂对生殖腺体细胞和生殖细胞系的表型参数产生不同的影响†
Abishankari Rajkumar,Trang Luu,Marc A Beal et al.
Abishankari Rajkumar et al.
The developmental and reproductive toxicity associated with exposure to phthalates has motivated a search for alternatives. However, there is limited knowledge regarding the adverse effects of some of these chemicals. We used high-content i...
Galectin-1 induces gene and protein expression related to maternal-conceptus immune tolerance in bovine endometrium† [0.03%]
半乳糖凝集素-1诱导与母体-胚胎免疫耐受相关的基因和蛋白在牛子宫内膜中的表达
Heather L Chaney,Lindsay F Grose,Jeanna M LaBarbara et al.
Heather L Chaney et al.
Conceptus secretory factors include galectins, a family of carbohydrate binding proteins that elicit cell adhesion and immune suppression by interacting with intracellular and extracellular glycans. In rodents, galectin-1 (LGALS1) promotes ...
Long non-coding RNA NRSN2-AS1 facilitates tumorigenesis and progression of ovarian cancer via miR-744-5p/PRKX axis [0.03%]
长链非编码RNA NRSN2-AS1通过miR-744-5p/PRKX轴促进卵巢癌的肿瘤发生及进展
Qian Chen,Jia Xie,Yisi Yang
Qian Chen
Newly discovered lncRNA neurensin-2 antisense RNA 1 (NRSN2-AS1) has not been well explored in cancers. Ovarian cancer (OV) is a primary gynecologic cancer worldwide and has the highest mortality rate among gynecologic cancers. Hence, the ro...