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期刊名:Nature immunology

缩写:NAT IMMUNOL

ISSN:1529-2908

e-ISSN:1529-2916

IF/分区:27.6/Q1

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共收录本刊相关文章索引4583
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Jeong-Mi Lee,Paulo Lisboa Raeder,Ridwan B Rashid et al. Jeong-Mi Lee et al.
Follicular regulatory T (TFR) cells restrain follicular helper T (TFH) cell-mediated B cell responses to optimize humoral immunity while limiting autoimmunity. Here we assessed the developmental dynamics of TFR cells. We found that TFR cell...
Wael Traboulsi,Pankaj Gaur,Subhadip Kundu et al. Wael Traboulsi et al.
CD8+ central memory T (TCM) cells provide stronger antitumor immunity than more-differentiated effector memory counterparts. Here we show that poly(ADP-ribose) polymerase (PARP) inhibition induces CD8+ TCM cells with superior memory by acti...
Yanan Hu,Lianfu Wu,Sihao Qu et al. Yanan Hu et al.
Eosinophils are multifunctional granulocytes involved in immune regulation, metabolism and tissue repair; however, the extent of their heterogeneity across tissues and the principles governing their specialization are not well defined. Here...
Jayashree Srinivasan,Colin R Moore,Aparna Calindi et al. Jayashree Srinivasan et al.
Dendritic cells are essential for establishing thymic central tolerance; however, mechanisms supporting their homeostasis and activation remain unresolved. Through single-cell transcriptomics and functional assays, we identify seven thymic ...
Yasuharu Haku,Koji Kitaoka,Koki Ichimaru et al. Yasuharu Haku et al.
Glycolysis and mitochondrial fatty acid oxidation (FAO) regulate CD8+ T cell differentiation, but how this metabolic balance regulates T cell exhaustion is unclear. PD-1 signaling inhibits glycolysis and enhances FAO. Here, we show that CD8...