TSLP promotes GATA3-expressing effector regulatory T cells via DC2 derived from transitional DCs [0.03%]
TSLP通过过渡型DC衍生的DC2促进GATA3表达效应调节性T细胞
Marine Guivarch,Pierre Meyer,Antoine Braud et al.
Marine Guivarch et al.
Thymic stromal lymphopoietin (TSLP), initially described as a driver of type 2 helper T cell responses, can also act on dendritic cells (DCs) to promote the generation and accumulation of GATA3-expressing effector regulatory T (eTreg) cells...
Clonal CD8+ T cells populate the leptomeninges and coordinate with immune cells in human degenerative brain diseases [0.03%]
克隆性CD8+T细胞定植在人类退行性脑病的蛛网膜下腔并与其免疫细胞相互协调作用
Ryan Hobson,Samuel H S Levy,Chitra Mohinder Singh Singal et al.
Ryan Hobson et al.
Meningeal immune cells monitor the central nervous system (CNS) and influence neuroinflammation in mice, but the human leptomeningeal immune landscape and the changes that occur in this immunological niche in neurodegeneration remain undere...
Hannah E Ennerfelt,Katrin I Andreasson
Hannah E Ennerfelt
Author Correction: Long COVID involves activation of proinflammatory and immune exhaustion pathways [0.03%]
作者更正：长新冠涉及激活促炎症和免疫耗竭途径
Malika Aid,Valentin Boero-Teyssier,Katherine McMahan et al.
Malika Aid et al.
Published Erratum
Nature immunology. 2026 Jan 23. DOI:10.1038/s41590-026-02438-1 2026
Author Correction: Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells [0.03%]
作者更正：抗原和细胞因子通过抑制自噬作用塑造CD8 T细胞的线粒体、迁移和效应器装置
Linda V Sinclair,Tom Youdale,Laura Spinelli et al.
Linda V Sinclair et al.
Published Erratum
Nature immunology. 2026 Jan 20. DOI:10.1038/s41590-026-02433-6 2026
Author Correction: DC subsets and states unraveled across human juxtatumoral and malignant tissues [0.03%]
作者更正：人类紧邻肿瘤和恶性组织中的DC亚群和状态的解析
Kevin Mulder,Margaux Gardet,Wan Ting Kong et al.
Kevin Mulder et al.
Published Erratum
Nature immunology. 2026 Jan 20. DOI:10.1038/s41590-026-02428-3 2026
Cell cycle arrest enhances CD8+ T cell effector function by potentiating glucose metabolism and IL-2 signaling [0.03%]
细胞周期阻滞通过增强葡萄糖代谢和IL-2信号转导来提高CD8⁺T细胞效应功能
Floortje J van Haften,Tetje C van der Sluis,Hanna S Hepp et al.
Floortje J van Haften et al.
Cell cycle-inhibiting chemotherapeutics are widely used in cancer treatment. Although the primary aim is to block tumor cell proliferation, their clinical efficacy also involves specific effector CD8+ T cells that undergo synchronized proli...
Unraveling CD8 lineage decisions reveals that functionally distinct CD8+ T cells are selected by different MHC-I thymic peptides [0.03%]
揭秘CD8谱系决定过程，揭示功能各异的CD8⁺T细胞通过不同的MHC-I胸腺肽段进行选择
Miho Shinzawa,Nicole Ramos,Khanh Bui et al.
Miho Shinzawa et al.
Thymocytes signaled by T cell antigen receptors to undergo positive selection acquire different functional fates while migrating through the thymus, but how this occurs remains uncertain. We now report that encoding CD8 co-receptors in both...