Author Correction: T cell egress via lymphatic vessels is tuned by antigen encounter and limits tumor control [0.03%]
作者更正:T细胞通过淋巴管的释放由抗原相遇调节并限制了肿瘤控制
Maria M Steele,Abhinav Jaiswal,Ines Delclaux et al.
Maria M Steele et al.
Published Erratum
Nature immunology. 2023 Apr;24(4):729. DOI:10.1038/s41590-023-01491-4 2023
Exhausted intratumoral Vδ2- γδ T cells in human kidney cancer retain effector function [0.03%]
耗竭的肿瘤内Vδ2-γδT细胞在人类肾癌中保留效应功能
Chiara Rancan,Marcel Arias-Badia,Pranay Dogra et al.
Chiara Rancan et al.
Gamma delta (γδ) T cells reside within human tissues including tumors, but their function in mediating antitumor responses to immune checkpoint inhibition is unknown. Here we show that kidney cancers are infiltrated by Vδ2- γδ T cells,...
Novel mouse models based on intersectional genetics to identify and characterize plasmacytoid dendritic cells [0.03%]
基于交联遗传学的新小鼠模型用于识别和表征浆细胞样树突状细胞
Michael Valente,Nils Collinet,Thien-Phong Vu Manh et al.
Michael Valente et al.
Plasmacytoid dendritic cells (pDCs) are the main source of type I interferon (IFN-I) during viral infections. Their other functions are debated, due to a lack of tools to identify and target them in vivo without affecting pDC-like cells and...
The X-linked epigenetic regulator UTX controls NK cell-intrinsic sex differences [0.03%]
X染色体表观遗传调控因子UTX控制NK细胞的性别差异
Mandy I Cheng,Joey H Li,Luke Riggan et al.
Mandy I Cheng et al.
Viral infection outcomes are sex biased, with males generally more susceptible than females. Paradoxically, the numbers of antiviral natural killer (NK) cells are increased in males. We demonstrate that while numbers of NK cells are increas...
IFNγ-induction of TH1-like regulatory T cells controls antiviral responses [0.03%]
干扰素-γ诱导的TH1型调节性T细胞控制抗病毒反应
Angela M Gocher-Demske,Jian Cui,Andrea L Szymczak-Workman et al.
Angela M Gocher-Demske et al.
Regulatory T (Treg) cells are an immunosuppressive population that are required to maintain peripheral tolerance and prevent tissue damage from immunopathology, via anti-inflammatory cytokines, inhibitor receptors and metabolic disruption. ...
MafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation [0.03%]
MafB限制的局部单核细胞增殖先于肺间质巨噬细胞分化
Domien Vanneste,Qiang Bai,Shakir Hasan et al.
Domien Vanneste et al.
Resident tissue macrophages (RTMs) are differentiated immune cells that populate distinct niches and exert important tissue-supportive functions. RTM maintenance is thought to rely either on differentiation from monocytes or on RTM self-ren...
Furong Qi,Dapeng Li,Zheng Zhang
Furong Qi
A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function [0.03%]
适应素LAT中单个氨基酸的取代加速TCR校对动力学并改变T细胞选择、维持和功能
Wan-Lin Lo,Miriam Kuhlmann,Gabrielle Rizzuto et al.
Wan-Lin Lo et al.
Mature T cells must discriminate between brief interactions with self-peptides and prolonged binding to agonists. The kinetic proofreading model posits that certain T-cell antigen receptor signaling nodes serve as molecular timers to facili...
Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariants [0.03%]
感染天然SARS-CoV-2病毒可引发针对奥密克戎亚变体的广谱中和保护性抗体
Bin Ju,Qi Zhang,Ziyi Wang et al.
Bin Ju et al.
The omicron variants of SARS-CoV-2 have substantial ability to escape infection- and vaccine-elicited antibody immunity. Here, we investigated the extent of such escape in nine convalescent patients infected with the wild-type SARS-CoV-2 du...
Amanda G Fisher,Matthias Merkenschlager
Amanda G Fisher