Auditory Competition and Coding of Relative Stimulus Strength across Midbrain Space Maps of Barn Owls [0.03%]
脑桥空间地图中的听觉竞争和相对刺激强度的编码
Andrea J Bae,Roland Ferger,José L Peña
Andrea J Bae
The natural environment challenges the brain to prioritize the processing of salient stimuli. The barn owl, a sound localization specialist, exhibits a circuit called the midbrain stimulus selection network, dedicated to representing locati...
C9ORF72 Deficiency Results in Neurodegeneration in the Zebrafish Retina [0.03%]
C9ORF72缺陷导致斑马鱼视网膜神经退行性病变
Natalia Jaroszynska,Andrea Salzinger,Themistoklis M Tsarouchas et al.
Natalia Jaroszynska et al.
Hexanucleotide repeat expansions within the gene C9ORF72 are the most common cause of the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). This disease-causing expansion leads to a reduction ...
Altered Hierarchical Gradients of Intrinsic Neural Timescales in Mild Cognitive Impairment and Alzheimer's Disease [0.03%]
轻度认知障碍和阿尔茨海默病患者固有神经时间尺度的层级梯度改变
Aiying Zhang,Kenneth Wengler,Xi Zhu et al.
Aiying Zhang et al.
Alzheimer's disease (AD) is a devastating neurodegenerative disease that affects millions of seniors in the United States. Resting-state functional magnetic resonance imaging (rs-fMRI) is widely used to study neurophysiology in AD and its p...
An Aggressive Interaction Rapidly Increases Brain Androgens in a Male Songbird during the Non-breeding Season [0.03%]
一次激烈的相互作用可以迅速增加非繁殖期雄性歌曲鸟大脑中的雄性激素
Cecilia Jalabert,Sofia L Gray,Kiran K Soma
Cecilia Jalabert
Aggression is a crucial behavior that impacts access to limited resources in different environmental contexts. Androgens synthesized by the gonads promote aggression during the breeding season. However, aggression can be expressed during th...
Crystal N Li,Kevin A Keay,Luke A Henderson et al.
Crystal N Li et al.
Pain is considered a multidimensional experience that embodies not merely sensation, but also emotion and perception. As is appropriate for this complexity, pain is represented and processed by an extensive matrix of cortical and subcortica...
Belief Updating during Social Interactions: Neural Dynamics and Causal Role of Dorsomedial Prefrontal Cortex [0.03%]
社会互动中的信念更新：背内侧前额叶皮层的因果作用及神经动力学
Patricia Christian,Jakob Kaiser,Paul Christopher Taylor et al.
Patricia Christian et al.
In competitive interactions, humans have to flexibly update their beliefs about another person's intentions in order to adjust their own choice strategy, such as when believing that the other may exploit their cooperativeness. Here we inves...
Inhibitory Roles of Apolipoprotein E Christchurch Astrocytes in Curbing Tau Propagation Using Human Pluripotent Stem Cell-Derived Models [0.03%]
应用人多能干细胞衍生模型探究Christchurch型载脂蛋白E抑制Tau蛋白病扩散的作用机制
Rei Murakami,Hirotaka Watanabe,Hideko Hashimoto et al.
Rei Murakami et al.
Genetic variants in the apolipoprotein E (APOE) gene affect the onset and progression of Alzheimer's disease (AD). The APOE Christchurch (APOE Ch) variant has been identified as the most prominent candidate for preventing the onset and prog...
Cholinergic Neuromodulation of Prefrontal Attractor Dynamics Controls Performance in Spatial Working Memory [0.03%]
胆碱能神经调节前额皮层吸引子动态控制空间工作记忆表现
Alexandre Mahrach,David Bestue,Xue-Lian Qi et al.
Alexandre Mahrach et al.
The behavioral and neural effects of the endogenous release of acetylcholine following stimulation of the nucleus basalis (NB) of Meynert have been recently examined in two male monkeys (Qi et al., 2021). Counterintuitively, NB stimulation ...
Mahdiyar Shahbazi,Giacomo Ariani,Mehrdad Kashefi et al.
Mahdiyar Shahbazi et al.
When performing movements in rapid succession, the brain needs to coordinate ongoing execution with the preparation of an upcoming action. Here we identify the processes and brain areas involved in this ability of online preparation. Human ...
The Structural and Functional Integrity of Rod Photoreceptor Ribbon Synapses Depends on Redundant Actions of Dynamins 1 and 3 [0.03%]
Dynamin 1和3的冗余作用决定了视杆细胞信号盘突触结构与功能的完整性
Christin Hanke-Gogokhia,Thomas E Zapadka,Stella Finkelstein et al.
Christin Hanke-Gogokhia et al.
Vertebrate vision begins with light absorption by rod and cone photoreceptors, which transmit signals from their synaptic terminals to second-order neurons: bipolar and horizontal cells. In mouse rods, there is a single presynaptic ribbon-t...