Distinct Action Signals by Subregions in the Nucleus Accumbens during STOP-Change Performance [0.03%]
背侧和 ventral 贝尔核在停止变异表现过程中的不同动作信号
Sydney E Ashton,Paul Sharalla,Naru Kang et al.
Sydney E Ashton et al.
The nucleus accumbens (NAc) is thought to contribute to motivated behavior by signaling the value of reward-predicting cues and the delivery of anticipated reward. The NAc is subdivided into core and shell, with each region containing diffe...
Hailan Liu,Na Qu,Natalia Valdez Gonzalez et al.
Hailan Liu et al.
Light plays an essential role in a variety of physiological processes, including vision, mood, and glucose homeostasis. However, the intricate relationship between light and an animal's feeding behavior has remained elusive. Here, we found ...
Reactivation of prior responses drives serial dependence and stabilizes working memory representations [0.03%]
先前反应的激活驱动序列依赖性并稳定工作记忆表征
Ziyao Zhang,Jarrod A Lewis-Peacock
Ziyao Zhang
Serial dependence has shown seemingly contradictory effects on visual perception and working memory. While serial dependence promotes perpetual and mnemonic stability, it biases behavioral reports towards prior information. The neural mecha...
A Prelimbic Cortex-Thalamus Circuit Bidirectionally Regulates Innate and Stress-Induced Anxiety-Like Behavior [0.03%]
初边缘皮层-丘脑环路双向调节本能和应激诱发的类似焦虑的行为
Sheng-Rong Zhang,Ding-Yu Wu,Rong Luo et al.
Sheng-Rong Zhang et al.
Anxiety-related disorders respond to cognitive behavioral therapies, which involved the medial prefrontal cortex (mPFC). Previous studies have suggested that subregions of the mPFC have different and even opposite roles in regulating innate...
Tracking the misallocation and reallocation of spatial attention towards auditory stimuli [0.03%]
跟踪空间注意分配给听觉刺激的不当和重新分配注意力
Ananya Mandal,Anna M Liesefeld,Heinrich R Liesefeld
Ananya Mandal
Completely ignoring a salient distractor presented concurrently with a target is difficult and sometimes attention is involuntarily attracted to the distractor's location (attentional capture). Employing the N2ac component as a marker of at...
Calcineurin and CK2 Reciprocally Regulate Synaptic AMPA Receptor Phenotypes via α2δ-1 in Spinal Excitatory Neurons [0.03%]
钙调磷酸酶和CK2通过α2δ-1在脊髓兴奋性神经元中相互调节突触AMPA受体类型
Yuying Huang 黄玉莹,Jian-Ying Shao 邵建英,Hong Chen 陈红 et al.
Yuying Huang 黄玉莹 et al.
Calcineurin inhibitors, such as cyclosporine and tacrolimus (FK506), are commonly used immunosuppressants for preserving transplanted organs and tissues. However, these drugs can cause severe and persistent pain. GluA2-lacking, calcium-perm...
The Small G-Protein Rac1 in the Dorsomedial Striatum Promotes Alcohol-Dependent Structural Plasticity and Goal-Directed Learning in Mice [0.03%]
小G蛋白Rac1通过背内侧纹状体介导的酒精依赖性结构可塑性促进小鼠目标导向学习
Zachary W Hoisington,Alexandra Salvi,Sophie Laguesse et al.
Zachary W Hoisington et al.
The small G-protein Ras-related C3 botulinum toxin substrate 1 (Rac1) promotes the formation of filamentous actin (F-actin). Actin is a major component of dendritic spines, and we previously found that alcohol alters actin composition and d...
β-arrestins are scaffolding proteins required for Shh-mediated axon guidance [0.03%]
ß-逮捕蛋白是Hh引导轴突所必需的支架蛋白
Rachelle Sauvé,Steves Morin,Patricia T Yam et al.
Rachelle Sauvé et al.
During nervous system development, Sonic hedgehog (Shh) guides developing commissural axons toward the floor plate of the spinal cord. To guide axons, Shh binds to its receptor Boc and activates downstream effectors such as Smoothened (Smo)...
Vishwa Goudar,Jeong-Woo Kim,Yue Liu et al.
Vishwa Goudar et al.
Interspecies comparisons are key to deriving an understanding of the behavioral and neural correlates of human cognition from animal models. We perform a detailed comparison of the strategies of female macaque monkeys to male and female hum...
Youssef Ezzyat,Abby Clements
Youssef Ezzyat
People parse continuous experiences at natural breakpoints called event boundaries, which is important for understanding an environment's causal structure and for responding to uncertainty within it. However, it remains unclear how differen...