Punishments enhance reward learning by modulating striatal prediction errors [0.03%]
惩罚通过调节纹状体预测误差来增强奖赏学习
J Carvalheiro,F Queirazza,L Pesonen et al.
J Carvalheiro et al.
People often make decisions in contexts where rewards and punishments co-occur, yet most human research still examines reward and punishment learning as independent processes. Here, across three studies, we address this gap by demonstrating...
β-bursting as a sensitive neural marker of inhibitory control in healthy older adults: a linear mixed-effects modelling and threshold-free cluster approach [0.03%]
线性混合效应模型和无阈值集群方法在健康老年人抑制控制敏感神经标记β振荡中的应用研究
Aliya C M Warden,Damian Cruse,Craig J McAllister et al.
Aliya C M Warden et al.
Inhibitory control is essential for adaptive behaviour and declines with age, yet the underlying neural dynamics remain poorly understood. The β-rhythm (15-29 Hz) is associated with inhibitory signalling within the fronto-basal ganglia net...
Spinal processing of spatiotemporally diverse tactile stimuli: Computational insights into allodynia and spinal cord stimulation [0.03%]
脊髓处理时空多样的触觉刺激:全部疼痛和脊髓刺激的计算见解
Laura Medlock,Steven A Prescott
Laura Medlock
Weakening of synaptic inhibition in the spinal dorsal horn contributes to mechanical allodynia after peripheral nerve pathology. Restoring inhibition can alleviate allodynia whereas weakening it is sufficient to induce allodynia and spontan...
The role of disulfide bonds in the GluN1 subunit in the early trafficking and functional properties of GluN1/GluN2 and GluN1/GluN3 NMDA receptors [0.03%]
胱硫醚 bridges 在 GluN1 亚基早期转运和功能特性中的作用:GluN1/GluN2 和 GluN1/GluN3 N-甲基-D-天冬氨酸受体
Jakub Netolicky,Seungha Lee,Petra Zahumenska et al.
Jakub Netolicky et al.
N-methyl-D-aspartate receptors (NMDARs) are ionotropic glutamate receptors essential for excitatory neurotransmission. Previous studies proposed the existence of four disulfide bonds in the GluN1 subunit; however, their role in NMDAR traffi...
Concurrent multimodal imaging demonstrates that EEG-based excitation/inhibition balance reflects glutamate and GABA balance [0.03%]
同时多模态影像学证明了基于脑电图的兴奋/抑制平衡反映了谷氨酸和GABA的平衡
Aaron Cochrane,Luke Rosedahl,Masako Tamaki et al.
Aaron Cochrane et al.
Magnetic Resonance Spectroscopy (MRS)-derived excitation/inhibition (E/I) ratio is recognized as a valuable index of attentional modulation, the plasticity and stability of learning states, and disordered functioning. Inferring the E/I rati...
Integration of memory and sensory information in skilled sequence production [0.03%]
熟练序列产生过程中的记忆和感觉信息的整合
Amin Nazerzadeh,Medha Porwal,J Andrew Pruszynski et al.
Amin Nazerzadeh et al.
Sequential movements rely on two information sources: external sensory cues and internal memory representations. Although often both sources jointly drive sequential behavior, previous research has primarily examined them in isolation. To a...
The tuned cortex: Convergent expertise-related structural and functional remodeling across the adult lifespan [0.03%]
调谐的大脑皮层:贯穿整个生命周期的结构和功能重塑收敛于专业技能相关的经验效应
Erik A Wing,Jordan A Chad,Geneva Mariotti et al.
Erik A Wing et al.
Neuroplasticity is a defining property of the brain. Structural and functional brain changes arise soon after learning and are particularly evident following years of practice that underpin expert performance. Much existing evidence comes f...
Edinger-Westphal neurons contribute to emergence from desflurane and sevoflurane anesthesia in mice [0.03%]
艾丁格-温施法神经元参与了小鼠从地氟烷和异氟烷麻醉中恢复清醒的过程
Yiwen Hu 胡译文,Jing Huang 黄静,Fuhai Bai 白福海 et al.
Yiwen Hu 胡译文 et al.
Most general anesthetics have long been believed to work by exerting a wide range of inhibitory impacts on the central nervous system, yet accumulating evidence has highlighted their excitatory effects-particularly that multiple anesthetics...
Delayed, Reduced and Redundant: Information Processing of Prediction Errors during Human Sleep [0.03%]
延迟、减少和冗余:人类睡眠期间对预测误差的信息处理
Christine Blume,Marina Dauphin,Maria Niedernhuber et al.
Christine Blume et al.
During sleep, the human brain transitions to a 'sentinel processing mode', enabling the continued processing of environmental stimuli despite the absence of consciousness. We employed advanced information-theoretic analyses, including mutua...
Binocular Circuitry as a Model for Understanding Experience-Dependent Circuit Development across the Mammalian Cortex [0.03%]
二元视觉回路作为理解经验依赖性环路发育的模型穿越哺乳动物皮层
Jingxi Zhao,Chuying Zhou,Na Zhou et al.
Jingxi Zhao et al.
The binocular circuitry in mammals (e.g., mice, cats, and primates) integrates two distinct visual cortical circuitries-the contralateral and ipsilateral eye circuitries-into a cohesive functional system for three-dimensional vision. These ...