Noninvasive Biomarkers for Assessing the Excitatory/Inhibitory Imbalance in Children with Epilepsy [0.03%]
非侵入性生物标志物在儿童癫痫患者中的应用评估兴奋性和抑制性的失衡状态
Sakar Rijal,F Kathryn King,Hmayag Partamian et al.
Sakar Rijal et al.
Epileptic seizures involve a cortical excitation-inhibition imbalance driven by dysfunctional interneurons that contribute to gamma oscillations generation. While impaired gamma oscillations are commonly reported in epilepsy, the dynamics o...
Tonic GABA and Glycine Inhibition Control Pain Hypersensitivity via Limiting α2δ-1- and mGluR5-Dependent NMDA Receptor Activity at Primary Afferent-Excitatory Neuron Synapses [0.03%]
生理盐水灌胃对血管性痴呆大鼠学习记忆障碍的影响及机制研究
Yuying Huang 黄玉莹,Hong Chen 陈红,Shao-Rui Chen 陈少瑞 et al.
Yuying Huang 黄玉莹 et al.
Impaired synaptic inhibition by GABA and glycine contributes to excitatory-inhibitory imbalance in the spinal cord associated with chronic neuropathic pain; however, the underlying mechanisms remain unclear. In this study, we investigated h...
Theta activity supports landmark-based correction of naturalistic human path integration [0.03%]
基于标志物的人类自然场景路径整合修正效应及其脑电theta振荡机制
Clément Naveilhan,Raphaël Zory,Klaus Gramann et al.
Clément Naveilhan et al.
How do humans integrate landmarks to update their spatial position during active navigation? Using immersive virtual reality and high-density mobile EEG, we investigated the neural underpinnings of landmark-based recalibration during path i...
Linking connectivity dynamics to symptom severity and cognitive abilities in children with autism spectrum disorder: An fNIRS study [0.03%]
一项关于自闭症谱系障碍儿童连接动力学与症状严重程度和认知能力的研究：fNIRS研究
Conghui Su,Yubin Hu,Yifan Liu et al.
Conghui Su et al.
Functional near-infrared spectroscopy (fNIRS) has emerged as a valuable tool for investigating neurobiological markers in children with autism spectrum disorder (ASD). While previous studies have identified abnormal functional connectivity ...
Synaptic properties of layer 6 auditory corticothalamic inputs in normal hearing and noise-induced hearing loss [0.03%]
正常听力和噪声性听力损失下的听觉皮层-丘脑投射的突触特性
Yanjun Zhao,Brandon Bizup,Thanos Tzounopoulos
Yanjun Zhao
Layer 6 corticothalamic neurons (CTs) provide strong feedback input that is crucial to perception and cognition in normal and pathological states; however, the synaptic properties of this input remain largely unknown, especially in patholog...
Origins of the Auditory Brainstem Response in Mice Using Source Localization of Topographic Multichannel EEG [0.03%]
基于拓扑多通道脑电地形图定位的老鼠听性脑干反应的起源研究
Xue Wang,Andrej Kral,Rüdiger Land
Xue Wang
The auditory brainstem response (ABR) is a critical tool for assessing auditory brainstem function in biomedical mouse models. Remarkably, despite its importance, the origins of ABR waves specific to mice remain poorly identified. Here, we ...
Alpha-band activity tracks reflexive changes in the breadth of the zoom lens of attention [0.03%]
α波活动范围反映了注意广度的反射变化
Dirk van Moorselaar,Jan Theeuwes,Stefan Van der Stigchel
Dirk van Moorselaar
Spatial attention is often conceptualized as a flexible "zoom lens" that can dynamically adjust its focus, but most evidence stems from studies of voluntary attention. Our study investigates whether involuntary, reflexive attention exhibits...
Distinct portions of superior temporal sulcus combine auditory representations with different visual streams [0.03%]
听觉与不同视觉通道的表征在颞上沟的不同区域结合在一起
Gabriel Fajardo,Mengting Fang,Stefano Anzellotti
Gabriel Fajardo
In humans, the superior temporal sulcus (STS) combines auditory and visual information. However, the extent to which it relies on visual information from the ventral or dorsal stream remains uncertain. To address this, we analyzed open-sour...
TREK1 channels shape spindle-like oscillations, neuronal activity, and short-term synaptic plasticity in thalamocortical circuits [0.03%]
TREK1通道塑造丘脑皮层回路中的纺锤形振荡、神经元活动和短期突触可塑性
Afsaneh Labbaf,Valérie Krauth,Nicole Rychlik et al.
Afsaneh Labbaf et al.
Although TREK1 channels are widely expressed in several thalamic nuclei, the role of this K2P family member in modulating thalamic cell excitability and physiological thalamocortical oscillatory activity is not well studied. Here we explore...