Co-release of GABA and ACh from medial olivocochlear neurons as a fine regulatory mechanism of cochlear efferent inhibition [0.03%]
耳蜗核神经元同时释放GABA和ACh：耳蜗传出抑制的精细调控机制
Tais Castagnola,Valeria C Castagna,Lester Torres Cadenas et al.
Tais Castagnola et al.
During development, inner hair cells (IHCs) in the mammalian cochlea are unresponsive to acoustic stimuli but instead exhibit spontaneous activity. During this same period, neurons originating from the medial olivocochlear (MOC) complex tra...
Noise-induced hearing loss enhances Ca2+-dependent electrical activity in lateral cochlear efferents [0.03%]
噪声引起的听力损失增强了外侧耳蜗效应神经元的钙离子依赖性电活动
Hui Hong 洪卉,Laurence O Trussell
Hui Hong 洪卉
Exposure to loud and/or prolonged noise damages cochlea and triggers downstream brain changes, resulting in hearing loss and altered speech comprehension. It remains unclear however whether noise exposure also compromises the cochlear effer...
Collapsing perisomatic inhibition leads to epileptic fast ripple oscillations caused by pseudosynchronous firing of CA3 pyramidal neurons [0.03%]
皮层下放电导致CA3锥体神经元假同步发放及快涟漪振荡产生
Dániel Schlingloff,Tamás F Freund,Balázs Hangya et al.
Dániel Schlingloff et al.
Diverse network oscillations, thought to represent different information processing modes of cortical networks, are accompanied by synchronous neuronal activity at various temporal scales. Sharp wave associated ripple oscillations, supporti...
Annual Renewal: Why the Society for Neuroscience Meeting Keeps Drawing Me Back [0.03%]
年度回顾：是什么让我年复一年地参加神经科学学会年会
Indira M Raman
Indira M Raman
Registering for my 35th consecutive Society for Neuroscience Annual Meeting in early July 2025, I realized the Conference is the longest standing yearly ritual of my life. I couldn't help wondering, why do I keep doing it? Is it duty or des...
Microsaccade direction reveals the variation in auditory selective attention processes [0.03%]
微眼跳的方向揭示了听觉注意力选择过程的差异
Shimpei Yamagishi,Shigeto Furukawa
Shimpei Yamagishi
Selective spatial attention plays a critical role in perception in the daily environment where multiple sensory stimuli exist. Even covertly directing attention to a specific location facilitates the brain's information processing of stimul...
Common Mechanism Underlying Synaptic Dysfunction Caused by Preformed Fibril-Induced Accumulation of α-Synuclein or Tau in a Culture Propagation Model [0.03%]
以细胞培养传播模型为基础，探究α-突触核蛋白或tau预形成原纤维诱导聚集导致突触功能障碍的共同机制
Dimitar Dimitrov,Sruthi Raja,Humaira Noor et al.
Dimitar Dimitrov et al.
In sporadic neurodegenerative diseases, the endogenous proteins α-synuclein in Parkinson's disease and tau in Alzheimer's disease undergo pathogenic prion-like propagation over many years, accumulating in both soluble and insoluble forms i...
The Top-down of Prefrontal cortex to the Hippocampus Glutamatergic Pathway Regulates Reward memory of Methamphetamine [0.03%]
顶叶皮层下行到海马区谷氨酸能通路调控甲基苯丙胺奖赏记忆
Dongdong Zhao,Wenjing Shi,Minyu Li et al.
Dongdong Zhao et al.
Methamphetamine (METH) is a widely abused psychoactive drug that readily establishes reward memories contributing to METH relapse. The medial prefrontal cortex (mPFC) is central to cognition, motivation, reward and emotion and the hippocamp...
Sharp waves, bursts, and coherence: Activity in a songbird vocal circuit is influenced by behavioral state [0.03%]
尖波、爆发和一致性：行为状态影响鸣鸟发声回路的活动
Corinna Lorenz,Anindita Das,Eduarda Gervini Zampieri Centeno et al.
Corinna Lorenz et al.
Similar to motor skill learning in mammals, vocal learning in songbirds requires a set of interconnected brain areas that make up an analogous basal ganglia-thalamocortical circuit known as the anterior forebrain pathway (AFP). Although neu...
Xinyu Chen,Liyu Cao,Roy Eric Wieske et al.
Xinyu Chen et al.
Walking provides the motor foundation for navigation, while navigation ensures that walking is purposeful and adaptive to environmental contexts. Sensory processing of environmental information acts as the informational bridge that connects...
Rebound bursting selectively enables fast dynamics in dopamine midbrain neurons projecting to the dorso-lateral striatum [0.03%]
回弹放电选择性地使多巴胺中脑神经元的快速动力学得以实现，这些神经元向背外侧纹状体投射
Strahinja Stojanovic,Christopher J Knowlton,Richard Egger-Mackrodt et al.
Strahinja Stojanovic et al.
Dopamine midbrain (DA) neurons are involved in a wide array of key brain functions including movement control and reward-based learning. They are also critical for major brain disorders such as Parkinson Disease or schizophrenia. DA neurons...