Distortion Energy Drives Cellular and Mechanical Changes in Fibroblast-Seeded Collagen Scaffolds under Cyclic Loading [0.03%]
周期加载下成纤维细胞种子胶原支架中应变能驱动的细胞和力学变化
Amevi Semodji,Dalia DeLaCruz,Anamaria Zavala et al.
Amevi Semodji et al.
Fibroblast activity in soft tissues is highly regulated by the mechanical environment of the extracellular matrix. Physical thresholds that regulate fibroblast-mediated remodeling have been previously identified using stress or strain invar...
MR Elastography with Incremental Compressive Pre-Strain as a Method for Mapping Ex Vivo Brain Tissue Mechanical Properties [0.03%]
基于逐渐增加的压缩预应变的磁共振弹性成像法在离体脑组织模量图绘制中的应用研究
Olivia Bailey,Alexa M Diano,Ali H Lateef et al.
Olivia Bailey et al.
Traumatic brain injury (TBI), resulting from blunt or blast impact to the head, affects approximately 1.6 million Americans per year. Brain biomechanics and injury models play a fundamental role in the TBI community as they can be used to e...
Integrating Multiscale FE2M Simulations and Experiments to Predict Microcrack Damage in Cartilage [0.03%]
基于FE2M多尺度仿真和实验预测软骨微裂纹损伤
Kosar Safari,Ashkan Almasi,Phoebe Szarek et al.
Kosar Safari et al.
Articular cartilage, despite its resilience, is vulnerable to low-energy impacts that initiate microcracks within its collagen network, potentially leading to osteoarthritis (OA). This study integrates experimental evidence and a multiscale...
A Dissipative Particle Dynamics Investigation into Thrombosis Resistance of Charged Stent Designs [0.03%]
带电支架设计抗血栓形成的 dissipative particle dynamics 研究
Zhenmin Fan,Han Wu,Jian Wang et al.
Zhenmin Fan et al.
In-stent thrombosis remains a major challenge in cardiovascular interventions, leading to serious complications and reduced device efficacy. In this study, we propose a novel vascular stent design featuring a negatively charged coating to m...
Influence of Coronary Plaque Morphology on Local Mechanical States and Associated In-Stent Restenosis [0.03%]
冠状动脉斑块形态对局部力学状态及再狭窄的影响研究
Janina C Datz,Ivo Steinbrecher,Johannes Krefting et al.
Janina C Datz et al.
In-stent restenosis (ISR) after percutaneous coronary intervention is a multi-factorial process. Specific morphological lesion characteristics were observed to contribute to the occurrence of ISR. Local mechanical factors, such as stresses ...
Personalized Muscle Strength Improves Accuracy of Military Load Carriage Simulations [0.03%]
个性化肌肉强度可提高军事负重模拟的准确性
Anna Corman,Jordan Sturdy,Hedaya N Rizeq et al.
Anna Corman et al.
Military overuse injuries are often associated with load carriage, and poor physical fitness is a risk factor. However muscle strength is modifiable, which is important for injury prevention. Active-duty military populations are generally s...
Modeling of Radiofrequency Ablation and Electrosurgery: Capturing Tissue Carbonizaion and Stalling Phenomena [0.03%]
射频消融和电外科手术的建模：捕捉组织炭化和停滞现象
Junren Ran,Enrico Benedetti,Joseph Bentsman et al.
Junren Ran et al.
Radiofrequency ablation and electrosurgery are widely used in clinical practice. This study presents a comprehensive modeling framework for radiofrequency thermal therapies, incorporating both heat transfer and thermally induced state trans...
Impacts of Sterilization Method On Material Properties Of 3D Printable Resins With Prolonged Exposure To Cell Culture Environments [0.03%]
长时间暴露于细胞培养环境的3D打印树脂的消解方法对其材料特性的影响研究
Ashlee Liao,Michael Bennington,Kevin Dai et al.
Ashlee Liao et al.
Low-cost 3D printing has become increasingly important in biomedical research, enabling rapid fabrication of custom cell culture devices, fixtures, and biohybrid robotic components. However, little is known about how common sterilization pr...
A Pilot Study to Quantify In Vivo Meniscus Mechanics Under Load Using Magnetic Resonance Imaging [0.03%]
基于磁共振成像的膝关节内侧半月板在体机械性能的定量研究
Jamie Benson,Maelyn Arcodia,Isabelle Larche et al.
Jamie Benson et al.
Meniscus tears compromise its mechanical function, leading to impaired joint loading and, if left untreated, increase risk of further joint degeneration. Surgical repair can be successful for certain tear patterns. Establishing new methods ...
In-Vitro Evaluations of Shape Memory Polymer Scaffolds with Tunable Architecture for the Endovascular Embolization of Unruptured Intracranial Aneurysms [0.03%]
用于未破裂颅内动脉瘤血管内栓塞的结构可调形记忆聚合物支架的体外评价
Tanner L Cabaniss,Geoffrey P Colby,Yingtao Liu et al.
Tanner L Cabaniss et al.
Clinically relevant performance metrics for shape memory polymer (SMP) scaffolds intended for the endovascular treatment of intracranial aneurysms were evaluated in various in-vitro experiments. Multiple SMP formulations were first evaluate...