Quantifying Porosity-Linked Mechanical Behaviour of Renal Tubular Epithelial Cells by Poroviscoelastic Modelling and AFM Nanoindentation [0.03%]
基于_poroviscoelastic_建模和AFM纳米压入的肾小管上皮细胞孔隙度相关力学行为量化研究
Lei Wang,Wenhui Liu
Lei Wang
Understanding the permeability characteristics of renal tubular epithelial cells is essential for exploring the mechanobiological regulation of solute and fluid transport in kidney physiology. In this study, we investigated the depth-depend...
Machine Learning Methods to Predict Unmeasured Muscle Activation in Upper Limb Reaching Task for Assessing Population-Level Cross-Subject Generalizability [0.03%]
用于上肢到达任务中未测量肌肉激活预测的机器学习方法及其跨受试者泛化能力评估研究
Baivab Bhandari,Shadman Tahmid,James Yang
Baivab Bhandari
Accurately estimating muscle activation remains a fundamental challenge in neuromuscular modeling, particularly when measurements are limited by sensor placement, noise, and accessibility constraints. Traditional methods, such as Inverse Dy...
Expanded stoichiometric model of chondrocyte metabolism: response to cyclical shear and compressive loading [0.03%]
软骨细胞代谢的扩展计量模型:对周期性剪切和压缩载荷的响应
Aubrey Kimmel,Adrienne Arnold,Ayten Erdogan et al.
Aubrey Kimmel et al.
Cartilage deterioration is a hallmark osteoarthritis, and there is substantial interest in developing strategies for cartilage repair. Cyclical mechanical stimulation has been known for decades to drive synthesis of cartilage matrix protein...
Design and Evaluation of An Integrated Piezoelectric Force Sensing Total Knee Replacement [0.03%]
一种集成压电式力敏膝关节置换的设计与评价
Brandon D Hines,Ryan Willing,Steven R Anton
Brandon D Hines
With patient dissatisfaction rates in total knee arthroplasty currently at 20%, smart knee technology seeks to provide an in vivo methods for tracking postoperative joint forces, which could aid in early diagnosis of postoperative complicat...
Multi-Objective Optimization Design of Synthetic Polymer Heart Valve Geometry [0.03%]
合成聚合物心脏瓣膜几何结构的多目标优化设计
Lu Chen,Jingyuan Zhou,Zhuo Zhang et al.
Lu Chen et al.
Background: Polymeric heart valves (PHVs) face critical trade-offs between durability and hemodynamics. This study aimed to improve the flow, leakage, and stress distribution of a polyurethane-based valve by simultaneousl...
Maturation-Dependent Tendon Mechanical and Structural Response to Overload in Rat Model of Synergistic Ablation [0.03%]
协同切除大鼠模型中肌腱成熟度依赖性过载的力学和结构反应
Lily M Lin,Hailey Bonelli,Dawn M Elliott
Lily M Lin
Aging musculoskeletal tissues have progressively declining ability to maintain homeostasis, increasing the risk for tendinopathy and tendon rupture. In young rats (3 months old), in vivo mechanical overload induced adaptive changes at 8 wee...
An In Vitro Study of Embolus Migration in an Anatomical Cerebrovascular Model [0.03%]
一项有关血管栓子迁移的离体解剖模型研究
Saurabh Bhardwaj,Daniel Khalil,Jose Monclova et al.
Saurabh Bhardwaj et al.
Acute ischemic stroke (AIS) remains a driver of mortality and long-term impairment, with clinical outcomes depending strongly on the final lodging site of emboli within the cerebrovasculature. However, the physical mechanisms governing embo...
Optimizing Marker Implantation for 3D Kinematic Tracking in X-ray Videos [0.03%]
基于X射线视频的三维运动捕捉中标志物植入优化研究
Julia Wildau,Emanuel Andrada,Dirk Arnold
Julia Wildau
For a detailed analysis of complex movements, such as disturbed locomotion, a combination of common approaches is helpful (calculation of 3D kinematics, measurements of myoelectrical activities, and ground reaction forces). The use of inter...
Investigating Contact Models in Clavicle Fixation Plates: A Finite Element Study of Their Impact on Biomechanical Performance [0.03%]
锁骨接骨板接触模型的有限元研究及其对生物力学性能的影响分析
Abderrazak Kedadria,Lionel Gilson,Luc Rabet
Abderrazak Kedadria
Clavicle fractures are among the most common orthopedic injuries and frequently require plate fixation to restore anatomical alignment and mechanical stability. The biomechanical performance of fixation constructs is strongly influenced by ...
Physics-Informed Neural Network Assisted Extraction of Height-averaged Pulsatile Flow Velocity From Scalar Signal Transport in a Shallow Microfluidic Channel [0.03%]
基于物理的神经网络辅助从浅微流控通道标量信号传输中提取平均高度脉动流速
Yu-Xing Gong,Yi-Teng Wang,Jia-Guo Yin et al.
Yu-Xing Gong et al.
Accurate measurement of height-averaged flow velocity from scalar signal transport is important for shallow microfluidic velocimetry. Conventional scalar imaging velocimetry (SIV) is sensitive to scalar-field noise, while deep neural networ...