Brain-enriched guanylate kinase-associated protein in the spinal dorsal horn regulates mechanical allodynia in male mouse neuropathic and inflammatory pain model [0.03%]
脑源性鸟苷酸连接酶相关蛋白在外周神经病理性痛和炎症痛模型小鼠脊髓背角中的表达及其对机械痛觉过敏的调节作用
Tayo Katano,Akari Yoshikawa,Meiko Kawamura et al.
Tayo Katano et al.
Mechanical allodynia results from plastic changes in the central nervous system. Identifying the molecules involved in this plasticity is essential for understanding the mechanism of pathological pain. In a previous report, brain-enriched g...
Marital Status and High-Impact Pain Among Middle-Aged and Older Adults: A Population-Based Longitudinal Study in the United States [0.03%]
婚姻状况与中老年人高影响性疼痛的相关性:一项基于美国人口的纵向研究
Seung-Won Emily Choi,Brandon Wagner
Seung-Won Emily Choi
Despite the prevalence and importance of pain for public health, little is known about how social characteristics affect the experience of pain. Though marital relationships have well documented associations on mental and physical health, r...
Electrophysical resources for the treatment of acute perineal pain after vaginal delivery: a systematic review with meta-analysis [0.03%]
电物理资源在阴道分娩后急性会阴痛治疗中的作用:系统回顾和荟萃分析
Ana Carolina Sartorato Beleza,Cristine Homsi Jorge,Richard Eloin Liebano et al.
Ana Carolina Sartorato Beleza et al.
This systematic review aimed at synthesizing evidence regarding the effectiveness of electrophysical resources for perineal acute pain relief after vaginal delivery in the early post-partum period. Randomized controlled trials comparing ele...
Persistent neuropathic pain selectively impairs hedonic and motivational aspects of eating: insights from a mouse model [0.03%]
持久性神经病理性疼痛选择性地损害进食的快感和动机方面:来自小鼠模型的启示
Spring Valdivia,Patricia Veronica Agostino,Mirta Reynaldo et al.
Spring Valdivia et al.
Chronic pain is known to disrupt affective and motivational states, yet its impact on eating behavior-particularly the balance between homeostatic and reward-driven intake-remains poorly understood. Using the spared nerve injury (SNI) model...
Assessing Relationships Between Cognition, Sleep, and Mental Health in Pediatric Patients with Chronic Pain [0.03%]
评估慢性疼痛儿科患者的认知、睡眠和精神健康之间的关系
Nicole Tacugue,Nathan Cashdollar,Edin Randall et al.
Nicole Tacugue et al.
Chronic pain in adolescents commonly disrupts cognitive functioning, sleep, and mental health. Research suggests underdeveloped cognitive skills in adolescents may lead to poor self-management thus reinforcing pain-related disability. This ...
A neural pattern for fear of neck movement: Development and response to targeted treatment [0.03%]
颈部运动恐惧的神经模式:发育和针对目标治疗的反应
Carlos Murillo,Inge Timmers,Marina López-Sola et al.
Carlos Murillo et al.
Fear of movement is a main driver of disability and a key treatment target in chronic pain, though its neurobiological bases remain poorly understood. Here, we combine functional MRI with machine learning to identify and evaluate a brain pa...
Amygdalar Calcitonin Gene-Related Peptide Driven Effects of Cold Sensitivity Induced by Peripheral Neuropathy in Mice [0.03%]
冷刺激诱发的外周神经病理性疼痛的小鼠模型中杏仁体中的降钙素基因相关肽的作用机制研究
Alexis D Trail,Heather N Allen,Blesson Paul et al.
Alexis D Trail et al.
The central nucleus of the amygdala (CeA) is a critical regulator of nociception, and its role in pain modulation depends on factors such as hemispheric location, neuropeptide release, and experimental model. Calcitonin gene-related peptide...
Sex differences in pain-related behaviour and the endocannabinoid system following hind limb ischemia-reperfusion injury [0.03%]
后肢缺血再灌注损伤后的性别差异痛行为及内源大麻素系统的影响
Catherine R Healy,Maria C Redmond,Georgina Gethin et al.
Catherine R Healy et al.
Ischemia-reperfusion (I/R) injury causes tissue damage in organ transplantation, stroke and myocardial infarction, and underlies chronic wound formation. The endocannabinoid system (ECS) is involved in pain modulation, maintenance of skin h...
Non-Pharmacological Interventions for Managing Sickle Cell Crisis Pain: A Qualitative Study on Adolescents' and Caregivers' Experiences [0.03%]
非药物干预在镰状细胞病疼痛危象管理中的应用:一项关于青少年及照料者经历的定性研究
Bukola Mary Ibitoye,Bernie Garrett,Manon Ranger et al.
Bukola Mary Ibitoye et al.
Sickle cell crisis (SCC), characterized by recurrent acute pain episodes, is the most common reason for hospitalization among adolescents with sickle cell disease (SCD), a common hemoglobinopathy in Nigeria. SCC pain is challenging to manag...
Prevalence of musculoskeletal pain in primary care - a study on Swedish children and young people [0.03%]
瑞典儿童和青少年主诉肌肉骨骼疼痛的流行病学研究-一项初级保健的研究
Matilda Ebel,Beata Borgström Bolmsjö,Elisabeth Bondesson et al.
Matilda Ebel et al.
Musculoskeletal pain is a common complaint among children and young people, and primary care services are typically the first contact when seeking medical care. The main objective of this study was to investigate the prevalence of musculosk...