Evaluation of cytotoxic and genotoxic effects of nicotine, tobacco-specific nitrosamines, and dried tobacco leaf extract on HepG2 [0.03%]
尼古丁、烟草特有亚硝胺和干烟叶提取物对HepG2细胞毒性和遗传毒性作用的评价
Malu Siqueira Borges,Ana Letícia Hilário Garcia,Enaile Tuliczewski Serpa et al.
Malu Siqueira Borges et al.
During the tobacco crop sorting process, workers come in contact with various substances found in dried leaves, including tobacco-specific nitrosamines: N'-nitrosonornicotine (NNN), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), and ...
Hymenaea courbaril hydroalcoholic extract protects in vivo against oxidative stress in Caenorhabditis elegans via DAF-2 and SKN-1 [0.03%]
Hymenaea courbaril 水乙醇提取物通过DAF-2和SKN-1保护线虫活体免受氧化应激损伤
Larissa Aline Carneiro Lobo,Péterson Alves Santos,Thais Lemos Mendes et al.
Larissa Aline Carneiro Lobo et al.
Hymenaea courbaril L. (H. courbaril) is a South American native species frequently used to treat various symptoms and illnesses, including anemia, fatigue, inflammation, pain, respiratory conditions, kidney and prostate disorders, cancer, d...
Antibacterial activity of essential oil from Zingiber officinale Roscoe against Xanthomonas strains: chemical composition and docking study of α-zingiberene [0.03%]
抗菌活性：化学成分和对接研究
Gleiciane C S Pereira,Cassia C Fernandes,Jardel Lopes Pereira et al.
Gleiciane C S Pereira et al.
Ginger rhizomes (Zingiber officinale Roscoe) have been used for treating several diseases including headaches, colds, nausea, and emesis. Considering the agrochemical potential of essential oil from ginger (EO-ZO), this study aimed to chemi...
Dual synergetic approach for targeting dysfunctional cells based on rare-earth-doped forsterite nanoparticles [0.03%]
一种基于稀土掺杂方柱橄榄石纳米颗粒针对功能异常细胞的双重协同策略
Rúbia Young Sun Zampiva,Claudir Gabriel Kaufmann Jr,Altevir Rossato Viana et al.
Rúbia Young Sun Zampiva et al.
In recent years, forsterite (Fo, Mg₂SiO₄) has emerged as a promising biomaterial for bone tissue engineering scaffolds, demonstrating efficacy in inhibiting the growth of clinical bacterial isolates. In addition, rare-earth (RE) doped Fo ...
Ecotoxicity of nicosulfuron and S-metolachlor-based herbicides on non-target plants [0.03%]
硝磺草酮和S-乙滴隆类除草剂对非靶标植物的生态毒理效应
Rafaela Carvalho de Souza,Leonardo Mendes Silva,Murilo Jovino Moraes et al.
Rafaela Carvalho de Souza et al.
Herbicides have been extensively researched due to widespread use in agriculture, consequently raising concerns regarding their environmental impact and potential adverse effects on non-target organisms, including humans. Nicosulfuron is a ...
Integrative assessment of the genotoxic effects of the neurotoxin saxitoxin produced by the freshwater cyanobacterium Raphidiopsis raciborskii [0.03%]
集草毒素（产生于淡水蓝藻的神经毒素）遗传毒性的综合评估
Cynthia Silva Porta,Ana Paula de Souza,Felipe Umpierre Conter et al.
Cynthia Silva Porta et al.
Saxitoxin (STX), a potent neurotoxin produced by cyanobacteria, has not been comprehensively investigated with respect to genotoxic potential, especially in freshwater environments. This study aimed to characterize the genotoxic potential o...
Combined anticancer effects of Chamaecytisus hirsutus extract and photodynamic therapy in Gastric cancer cells [0.03%]
光动力疗法联合毛蕊苕子提取物在胃癌细胞中的协同抗肿瘤作用
Metin Caliskan,Sercin Ozlem Caliskan,Emine Incilay Torunoglu et al.
Metin Caliskan et al.
The particular plant found in Türkiye, Chamaecytisus hirsutus ;(Fabaceae), has no studies examining its biological effects. Thus, the present study aimed to investigate the phytochemical composition, chemical profile, antioxidant activity,...
Toxicological safety, antioxidant effect, and chemoprotection determination of an extract from the babassu mesocarp (Orbignya phalerata Mart.) in preclinical studies [0.03%]
巴邦苏果肉（Orbignya phalerata Mart.）提取物的毒理安全性，抗氧化作用及化学保护作用的临床前研究确定
Nicole Debia,Ana Beatriz Santana Sousa,Beatriz Arêa Cassiano de Melo et al.
Nicole Debia et al.
Reactive nitrogen species (RNS) and reactive oxygen species (ROS) play a key role in chronic diseases and aging by initiating protein oxidation, impaired cellular membrane damage and functions, and induction of DNA mutations. When endogenou...
Genotoxicity of pure compounds and commercial formulations of the maize herbicides mesotrione and s-metolachlor in Vicia faba L [0.03%]
除草剂双氟磺草胺和S-间甲基氯禾熏原药及其制剂对菜豆的遗传毒性研究
Larissa Fonseca Andrade-Vieira,Sylvie Cotelle
Larissa Fonseca Andrade-Vieira
Herbicides containing the active components mesotrione and S-metolachlor persist in the environment and adversely affect non-target organisms. Therefore, it was of interest to examine the toxicological risk associated with these compounds. ...
Novel chemical constituents identified by UPLC-QTOF-MS/MS and biological activities attributed to extracts from three species of Mimosa [0.03%]
基于UPLC-QTOF-MS/MS鉴定的三种紫荆属植物中新型化学成分及其提取物的生物活性研究
Rodrigo Ferreira Santiago,Mariana Helena Chaves,João Paulo da Silva Gomes et al.
Rodrigo Ferreira Santiago et al.
The genus Mimosa (Fabaceae), includes approximately 540 species, some of which are popularly known as "Jurema" and are extensively used in traditional medicine. This study aimed to identify the chemical constituents and examine the antioxid...