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Evaluation of cytotoxic and genotoxic effects of nicotine, tobacco-specific nitrosamines, and dried tobacco leaf extract on HepG2

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During the tobacco crop sorting process, workers come in contact with various substances found in dried leaves, including tobacco-specific nitrosamines: N'-nitrosonornicotine (NNN), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), and nicotine (NIC). The... ...