Divergent myeloid and lymphoid immune landscapes in HPV/p16 positive and HPV/p16 negative oropharyngeal squamous cell carcinomas and their lymph node metastases [0.03%]
Raphaela Graessle,Iris Piwonski,Achim Franzen et al.
Raphaela Graessle et al.
Background: The tumor microenvironment of oropharyngeal squamous cell carcinoma (OPSCC) harbors diverse immune cell populations that influence tumor progression and patient outcome. ...
Microbiota-derived metabolites and cardiovascular implications in Inflammatory Bowel Disease (IBD) [0.03%]
Ivna Olić,Nikola Pavlović,Marko Kumrić et al.
Ivna Olić et al.
Background: Inflammatory bowel disease (IBD), encompassing Crohn's disease and ulcerative colitis, is a chronic relapsing systemic disorder associated with significant extraintestinal manifestations. Emerging evidence ind...
IL-6 triggers lysosomal degradation of LDL-R and enhances LDL-C uptake in vascular endothelial cells via macropinocytosis [0.03%]
Mulugeta M Zegeye,Jishamol T Veettil,Geena V Paramel et al.
Mulugeta M Zegeye et al.
Background: Endothelial dysfunction profoundly compromises the barrier function that precludes trans-endothelial entry of low-density lipoprotein cholesterol (LDL-C) into the vessel wall. LDL-C retention in the vessel wal...
Integrated in vitro and multi-cohort cross-omics analysis of HTLV-1-associated lung pathology reveals a RelA-dependent mechanism for monocyte recruitment and differentiation [0.03%]
Clément J F Heymann,Mieke Gouwy,Robin Hermans et al.
Clément J F Heymann et al.
Fludarabine disrupts the STAT1/AhR interaction to attenuate type 1 diabetes by inducing tolerogenic dendritic cells along with targeting effector T cells [0.03%]
Shan-Jie Rong,Chun-Liang Yang,Ke Xiao et al.
Shan-Jie Rong et al.
Impact of oxygen-ozone mixture on cellular functions: a biochemical perspective across cell types [0.03%]
氧气和臭氧混合物对细胞功能的影响：跨细胞类型的生化视角
Ayesha Khalid,Alessandra Sala,Antonella Forlino et al.
Ayesha Khalid et al.
Genetic epidemiology of C9orf72 repeat expansion associated amyotrophic lateral sclerosis in Hungary [0.03%]
匈牙利C9orf72重复扩增相关的肌萎缩侧索硬化遗传流行病学研究
Zsófia Flóra Nagy,Adrienn Géresi,Zoltán Grosz et al.
Zsófia Flóra Nagy et al.
Background: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive motor neuron loss. The most common genetic cause of ALS is the hexanucleotide repeat expansion in the C9or...
Immune landscape of gingivo-buccal oral cancer indicates high enrichment of immune-related gene sets in tumors of a large proportion of patients [0.03%]
免疫景观表明牙龈-颊口腔癌中大量患者肿瘤的免疫相关基因集富集度高
Debodipta Das,Arindam Maitra,Chinmay K Panda et al.
Debodipta Das et al.
Multi-parametric profiling of plasma-derived extracellular vesicles reveals a disease-associated molecular signature supporting a liquid biopsy approach in myelofibrosis [0.03%]
多参数血浆衍生外泌体分析揭示了一种疾病相关分子特征支持一种液体活检方法在骨髓纤维化中的应用
Ghazal Narimanfar,Husam B R Alabed,Alessia Brancolini et al.
Ghazal Narimanfar et al.
TNFα signaling in radiation-induced chronic bowel dysfunction suggests therapeutic potential for IBD biologics [0.03%]
辐射诱导的慢性肠道功能障碍中的TNFα信号转导提示了针对IBD生物制剂的治疗潜力
Sravani Devarakonda,Piyush Patel,Amelie Toft Morén et al.
Sravani Devarakonda et al.
Background: Pelvic radiation disease (PRD) arises from normal tissue damage following pelvic radiotherapy and often manifests as bowel dysfunction. Chronic low-grade inflammation is observed in the irradiated mucosa, but ...