Prevalence of ictal injuries in functional (psychogenic nonepileptic) seizures: A systematic review and meta-analysis [0.03%]
关于功能性（心理性非癫痫性）发作的痫样发作伤的流行率：系统回顾和meta分析
Adriana Boschi Moreira,André Enoch Knochenhauer,Giullia Victória Froehner et al.
Adriana Boschi Moreira et al.
Objective: Ictal injuries have long been considered typical signs of epileptic seizures. However, studies have shown that patients with functional seizures (FS)-also named psychogenic nonepileptic seizures-can also presen...
Meta-Analysis
Epilepsia. 2023 Nov;64(11):3082-3098. DOI:10.1111/epi.17752 2023
First unprovoked seizures among soldiers recruited to the Israeli Defense Forces during 10 consecutive years: A population-based study [0.03%]
以色列国防军10年内连续征召的新兵中第一次自发性癫痫发作的流行病学研究
Adili Tsur,Ronen Spierer,Renana Cohen et al.
Adili Tsur et al.
Objective: The management of patients after a first unprovoked seizure (FUS) can benefit from stratification of the average 50% risk for further seizures. We characterized subjects with FUSs, out of a large generally heal...
Seizure control in women with epilepsy undergoing assisted reproductive technology [0.03%]
辅助生育技术治疗癫痫女性的发作控制
Aisha A Abdulrazaq,Alessandra J Ainsworth,Jeffrey W Britton et al.
Aisha A Abdulrazaq et al.
The objective of this study was to determine seizure control in women with epilepsy (WWE) undergoing assisted reproductive technology (ART). Through retrospective chart review, WWE undergoing ART were identified. Demographics and details re...
Interictal high-frequency oscillations, spikes, and connectivity profiles: A fingerprint of epileptogenic brain pathologies [0.03%]
癫痫脑病灶的高频振荡、尖峰及连接模式：病理性标志物
Barbora Sklenarova,Eva Zatloukalova,Jan Cimbalnik et al.
Barbora Sklenarova et al.
Objective: Focal cortical dysplasia (FCD), hippocampal sclerosis (HS), nonspecific gliosis (NG), and normal tissue (NT) comprise the majority of histopathological results of surgically treated drug-resistant epilepsy pati...
Clinical severity is correlated with age at seizure onset and biophysical properties of recurrent gain of function variants associated with SCN8A-related epilepsy [0.03%]
临床严重程度与SCN8A相关性癫痫患儿的癫痫发作年龄及功能获得型突变的生物物理特性相关
Kyung Mi Chung,Joshua Hack,Jennifer Andrews et al.
Kyung Mi Chung et al.
Objective: Genetic variants in the SCN8A gene underlie a wide spectrum of neurodevelopmental phenotypes including several distinct seizure types and a host of comorbidities. One of the major challenges facing clinicians a...
De novo CLPTM1 variants with reduced GABAA R current response in patients with epilepsy [0.03%]
CLPTM1从头变异体可降低患者的GABAA受体电流反应以诱发癫痫症状
Nana Liu,Jinliang Li,Kai Gao et al.
Nana Liu et al.
Objective: To investigate the clinical features and potential pathogenesis mechanism of de novo CLPTM1 variants associated with epilepsy. Methods: ...
Prophecy or empiricism? Clinical value of predicting versus determining genetic variant functions [0.03%]
预测还是实证？预测遗传变异功能与确定遗传变异功能的临床价值比较
Andreas Brunklaus,Alfred L George Jr,Dennis Lal et al.
Andreas Brunklaus et al.
The recent explosion of epilepsy genetic testing has created challenges for interpretation of gene variants. Assessments of the functional consequences of genetic variants either by predictive or experimental strategies can contribute to es...
Text mining of electronic health records can validate a register-based diagnosis of epilepsy and subgroup into focal and generalized epilepsy [0.03%]
可通过文本挖掘电子健康记录来验证基于登记的癫痫诊断及其亚组分类为局灶性和全面性癫痫
Siri A Vulpius,Sebastian Werge,Isabella Friis Jørgensen et al.
Siri A Vulpius et al.
Objective: Combining population-based health registries and electronic health records offers the opportunity to create large, phenotypically detailed patient cohorts of high quality. In this study, we used text mining of ...
Economic evaluations of nonpharmacological treatments for drug-resistant epilepsy: A systematic review [0.03%]
难治性癫痫非药物治疗的经济学评价系统回顾
Hoi Yau Chan,Luca M M Janssen,Ben F M Wijnen et al.
Hoi Yau Chan et al.
This study was undertaken to systematically identify and critically appraise all published full economic evaluations assessing the cost-effectiveness of nonpharmacological interventions for patients with drug-resistant epilepsy. The Populat...
Safety, tolerability, and efficacy of adjunctive lacosamide in pediatric patients with epilepsy syndromes associated with generalized seizures: Phase 2, open-label exploratory trial [0.03%]
有关伴发全面性发作的癫痫综合征患儿辅用拉考沙胺片的安全性、耐受性和疗效：开放标签II期试验
Stéphane Auvin,Alexis Arzimanoglou,Cynthia Beller et al.
Stéphane Auvin et al.
Objective: To evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of lacosamide (LCM) (up to 12 mg/kg/day or 600 mg/day) as adjunctive therapy in pediatric patients with epilepsy syndromes associ...
Clinical Trial
Epilepsia. 2023 Nov;64(11):2947-2957. DOI:10.1111/epi.17741 2023