Temperature homeostasis disruption and hypothalamic alterations in experimental drug-resistant epilepsy [0.03%]
药物难治性实验癫痫的小鼠模型中体温调节中枢的改变及其机制研究
Rossella Di Sapia,Akash Bera,Omar Mamad et al.
Rossella Di Sapia et al.
Objective: Elevated body temperature may increase seizure risk, yet the relationship between thermoregulation and seizures, as well as the underlying mechanisms, remains poorly understood. We investigated whether thermore...
Variability in recommending epilepsy surgery across Level IV epilepsy centers in the United States [0.03%]
美国四级癫痫中心在推荐癫痫手术上的差异性
Avery R Caraway,Nancy A McNamara,Andrew T Knox et al.
Avery R Caraway et al.
Objective: Surgery is an effective, yet underutilized treatment for children with drug-resistant epilepsy. Although predictors of surgical outcomes are well described, the decision to recommend surgery varies by instituti...
Abnormal KCC2 expression and function in a mouse model of epilepsy and tuberous sclerosis complex [0.03%]
Tuberous Sclerosis复合异染性脑白质病小鼠模型中KCC2的表达和功能异常
Dongjun Guo,Lirong Han,Nicholas R Rensing et al.
Dongjun Guo et al.
Objective: Drug-resistant epilepsy is a common, severe manifestation of the genetic disorder tuberous sclerosis complex (TSC). Although significant mechanistic and therapeutic advances have been made in TSC, treatments fo...
Samhita Panda,Ronit Kumar Sahu,Mauli Ganatra et al.
Samhita Panda et al.
Autoimmune encephalitis usually presents with short-duration neuropsychiatric syndromes, mainly behavioral with cognitive dysfunction, recurrent seizures, and movement disorders. Among them, anti-LGI1 encephalitis has faciobrachial dystonic...
Case Reports
Epilepsia. 2026 Oct;67(10):e185-e190. DOI:10.1002/epi.70427 2026
Rapid eye movement sleep reduction in pediatric epilepsy: A propensity score-matched study [0.03%]
儿童癫痫的快速眼动睡眠减少：一项倾向性评分匹配研究
Alen Juginović,Laura Rodman
Alen Juginović
Objective: This study was undertaken to characterize sleep architecture assessed by polysomnography (PSG) in children with epilepsy versus matched nonepilepsy clinical comparators and disentangle disease from antiseizure ...
Nucleus basalis functional connectivity aberrations in temporal lobe epilepsy and improvements after successful epilepsy surgery [0.03%]
颞叶癫痫患者基底神经节功能连接异常及成功手术后的改善效应
Addison C Cavender,Derek J Doss,Ghassan S Makhoul et al.
Addison C Cavender et al.
Objective: Resective surgery achieves seizure freedom in approximately 60%-80% of patients with drug-resistant temporal lobe epilepsy (TLE), yet the extent to which seizure cessation permits recovery of disrupted function...
Lea Fisel,Nóra Pető,Sotirios Kalousios et al.
Lea Fisel et al.
Objective: Epileptic arousals (EAs) are seizures characterized solely by arousal from sleep. EAs are unrecognized in current seizure classifications. Their subtle semiology and inconsistently detectable ictal activity in ...
Outcomes of out-of-hospital treatment of impending tonic-clonic status epilepticus with diazepam nasal spray: A retrospective combined cohort analysis [0.03%]
关于鼻用地西泮治疗院外癫痫持续状态前兆的研究：回顾性合并队列分析
John M Stern,Leock Y Ngo,Eric B Segal et al.
John M Stern et al.
Objective: We assessed the timing, dosing, and effectiveness of diazepam nasal spray in a large dataset of seizures treated in the out-of-hospital setting, using as reference the International League Against Epilepsy crit...
Automated segmentation of postsurgical resection cavities on magnetic resonance imaging in focal epilepsy: A Multicentre Epilepsy Lesion Detection study [0.03%]
多中心癫痫病变检测研究中局灶性癫痫术后切除腔磁共振图像的自动分割
Jieun Seo,Mathilde Ripart,Helene Kaas et al.
Jieun Seo et al.
Objective: Quantitative assessment of extent of tissue resection following epilepsy surgery requires accurate delineation of the resection cavity on postoperative magnetic resonance imaging (MRI). Current methods for rese...
Moving beyond spike detection: High frequency-driven masking improves seizure onset zone localization in intracranial electroencephalography [0.03%]
超越尖峰检测：高频驱动的掩蔽改善颅内脑电图癫痫发作起始区定位
Amir Hossein Ayyoubi,Behrang Fazli Besheli,Valentina Hrtonova et al.
Amir Hossein Ayyoubi et al.
Objective: Interictal epileptiform spikes (IESs) are widely used biomarkers of epileptogenic tissue in presurgical epilepsy evaluation. However, their reliability for seizure onset zone (SOZ) localization in high-density ...