Trajectories of parent well-being in children with drug-resistant epilepsy [0.03%]
难治性癫痫患儿父母福祉的影响路径分析研究
Mary Lou Smith,Klajdi Puka,Kathy N Speechley et al.
Mary Lou Smith et al.
Objective: This longitudinal cohort study aimed to identify trajectories of parent well-being over the first 2 years after their child's evaluation for candidacy for epilepsy surgery, and to identify the baseline clinical...
Added value of corpus callosotomy following vagus nerve stimulation in children with Lennox-Gastaut syndrome: A multicenter, multinational study [0.03%]
迷走神经刺激联合扣带回切开术治疗兰诺克斯-加斯特劳夫综合征的附加价值：一项国际多中心研究
Jonathan Roth,Lottem Bergman,Alexander G Weil et al.
Jonathan Roth et al.
Objective: Lennox-Gastaut syndrome (LGS) is a severe form of epileptic encephalopathy, presenting during the first years of life, and is very resistant to treatment. Once medical therapy has failed, palliative surgeries s...
Multicenter Study
Epilepsia. 2023 Dec;64(12):3205-3212. DOI:10.1111/epi.17796 2023
The relationship between mood and anxiety and cognitive phenotypes in adults with pharmacoresistant temporal lobe epilepsy [0.03%]
药物抵抗的颞叶癫痫成人患者情绪和焦虑与认知表型之间的关系
Nolan Bingaman,Lisa Ferguson,Nicolas Thompson et al.
Nolan Bingaman et al.
Objective: Patients with temporal lobe epilepsy (TLE) are often at a high risk for cognitive and psychiatric comorbidities. Several cognitive phenotypes have been identified in TLE, but it is unclear how phenotypes relate...
Observational Study
Epilepsia. 2023 Dec;64(12):3331-3341. DOI:10.1111/epi.17795 2023
Telemedicine as a path to bridging inequities in patients with epilepsy [0.03%]
远程医疗在癫痫患者中均衡医疗不公平的作用路径分析
Ruta Yardi,Christopher J McLouth,Sally Mathias et al.
Ruta Yardi et al.
Objective: Access to epilepsy specialist care is not uniform in the USA, with prominent gaps in rural areas. Understanding the reasons for nonattendance at epilepsy appointments may help identify access hurdles faced by p...
Scoping review and expert-based consensus recommendations for assessment and management of psychogenic non-epileptic (functional) seizures (PNES) in children: A report from the Pediatric Psychiatric Issues Task Force of the International League Against Epilepsy [0.03%]
儿童心理性非癫痫发作（功能性发作）的评估和管理综述及专家共识建议：国际抗癫痫联盟儿科精神问题工作组报告
Colin Reilly,Nathalie Jette,Emma C Johnson et al.
Colin Reilly et al.
Limited guidance exists regarding the assessment and management of psychogenic non-epileptic seizures (PNES) in children. Our aim was to develop consensus-based recommendations to fill this gap. The members of the International League Again...
Natural language processing for identification of refractory status epilepticus in children [0.03%]
用于识别儿童难治性持续状态的自然语言处理
Fatemeh Mohammad Alizadeh Chafjiri,Latania Reece,Lillian Voke et al.
Fatemeh Mohammad Alizadeh Chafjiri et al.
Objective: Pediatric status epilepticus is one of the most frequent pediatric emergencies, with high mortality and morbidity. Utilizing electronic health records (EHRs) permits analysis of care approaches and disease outc...
Response: "What is the risk of unprovoked seizures after acute symptomatic status epilepticus?" [0.03%]
急性症状性癫痫持续状态后无诱因发作的风险是什么？
Estevo Santamarina,Marc Rodrigo-Gisbert,Laura Abraira et al.
Estevo Santamarina et al.
Lucas Johannes Rainer,Giorgi Kuchukhidze,Eugen Trinka et al.
Lucas Johannes Rainer et al.
Objective: Perception and recognition of emotions are fundamental prerequisites of human life. Patients with juvenile myoclonic epilepsy (JME) may have emotional and behavioral impairments that might influence socially de...
Astrocytic NKCC1 inhibits seizures by buffering Cl- and antagonizing neuronal NKCC1 at GABAergic synapses [0.03%]
天冬氨酸神经胶质细胞NKCC1通过缓冲Cl-和拮抗GABA能突触处的神经元NKCC1来抑制癫痫发作
Trong Dao Nguyen,Masaru Ishibashi,Adya Saran Sinha et al.
Trong Dao Nguyen et al.
Objective: A pathological excitatory action of the major inhibitory neurotransmitter γ-aminobutyric acid (GABA) has been observed in epilepsy. Blocking the Cl- importer NKCC1 with bumetanide is expected to reduce the neu...
Erez Berman,Natalia Erenburg,Ron Beloosesky et al.
Erez Berman et al.
Objective: In the absence of safety data in humans, the use of cannabidiol (CBD) is not recommended during pregnancy. Yet >50% of pregnancies in women with epilepsy are unintended, making fetal exposure to CBD possible. A...