Effects of continuous bipolar hippocampal deep brain stimulation on memory in patients with unilateral or bilateral refractory temporal lobe epilepsy [0.03%]
持续双极海马深部脑刺激对难治性一侧或双侧颞叶癫痫患者的记忆影响研究
Fernanda Lacerda Ortiz,Cristine Mella Cukiert,Julia Vescovi Vieira et al.
Fernanda Lacerda Ortiz et al.
Objective: To evaluate the long-term cognitive and memory outcomes in patients with drug-resistant temporal lobe epilepsy (TLE) treated with continuous hippocampal deep brain stimulation (Hip-DBS), particularly in individ...
Deep characterization of refractory epilepsy due to mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE) and insights into the role of invasive monitoring [0.03%]
轻度皮层发育畸形伴少突胶质细胞增生(MOGHE)难治性癫痫的深入研究及侵入性监测的作用探讨
Jean Khoury,Ingmar Blümcke,Robyn M Busch et al.
Jean Khoury et al.
Objective: Epilepsy surgery is an effective treatment option for patients with medically refractory epilepsy due to mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE). The success of surge...
Ictal-interictal continuum and status epilepticus: Two sides of the same coin? A prospective magnetic resonance imaging study [0.03%]
癫痫持续状态与癫痫发作-间期连续谱的关系:同一枚硬币的两面?一项前瞻性磁共振成像研究
Pilar Bosque-Varela,Lukas Machegger,Wanda Lauth et al.
Pilar Bosque-Varela et al.
Objective: Status epilepticus (SE) is the most severe expression of seizures, encompassing both SE with prominent motor symptoms and nonconvulsive SE (NCSE). Ictal-interictal continuum (IIC), an electroencephalographic ph...
Age- and sex-associated variability in lamotrigine prescription patterns and clearance [0.03%]
拉莫三嗪的处方模式和清除率与年龄和性别相关的变异性
Charul Avachat,Yuhan Long,Ashley Petersen et al.
Charul Avachat et al.
Objective: Lamotrigine is one of the most widely prescribed antiseizure medication (ASM) and mood stabilizer in the United States due to its favorable side-effect profile, lower risk of teratogenicity, and minimal drug-dr...
Responsive neurostimulation leads targeting intracranial sites with ictal high-frequency oscillation onset patterns are associated with better 2-year seizure control outcomes [0.03%]
电高频振荡起始模式的脑内刺激靶点与响应性神经调控2年疗效更佳有关
Doris Deng,Brian Jung,Lilit Mnatsakanyan et al.
Doris Deng et al.
Objective: Responsive neurostimulation (RNS) offers an effective and safe treatment for people living with refractory focal-onset epilepsy. Many RNS candidates need intracranial electroencephalography (IEEG) monitoring to...
Preclinical signal for a disease-modifying effect on seizure cluster severity with intermittent diazepam treatment [0.03%]
间断使用地西泮治疗可减轻癫痫发作簇的严重程度:一项概念验证研究
Qian Wu,Michelle Guignet,Jonathan Vuong et al.
Qian Wu et al.
Objective: In epilepsy, daily treatment provides only symptomatic seizure control, leaving a significant unmet need for a treatment that affects the underlying predisposition to seizures. Here, in a first-of-its-kind stud...
Response: "The importance of methodological context in pediatric VNS outcome reporting" [0.03%]
方法学背景在儿科迷走神经刺激治疗结局报告中的重要性回应
Lalit Bansal,Christian Kaufman,Ahmed Abdelmoity
Lalit Bansal
The importance of methodological context in pediatric vagus nerve stimulation outcome reporting [0.03%]
儿科迷走神经刺激结果报告的方法学背景的重要性
Thiemo F Dinger,Karim Mithani,George M Ibrahim
Thiemo F Dinger
Cross-cultural adaptation and validation of the Russian versions of the Global Assessment of Disability Related to Seizures and Global Assessment of Severity of Epilepsy scales [0.03%]
癫痫相关残疾全球评估和癫痫严重程度全球评估俄文版的跨文化改编及验证研究
Flora Rider,Alexander Turchinets,Mikhail Zinchuk et al.
Flora Rider et al.
Objective: The purpose of the study was to evaluate the usefulness and reliability of the Russian versions of the Global Assessment of Disability Related to Seizures (GADS) and Global Assessment of Severity of Epilepsy (G...
Lamotrigine is associated with a nonpathological increase in cardiac electrical conduction in people with and without heart disease [0.03%]
拉莫三嗪与特发性心脏电传导增加有关,在心脏病患者和非心脏病患者中均是如此
Justin M Ryan,Jonathan Mohnkern,Jorge Romero et al.
Justin M Ryan et al.
Objective: The US Food and Drug Administration (FDA) issued a warning that lamotrigine slows cardiac conduction, leading to arrhythmias in people with heart disease (HD). This is the first study to investigate the within-...