Long-term intellectual and developmental outcomes after pediatric epilepsy surgery: A systematic review and meta-analysis [0.03%]
儿童癫痫手术的长期智力和发育结局：系统评价和meta分析
Ilona Stefanos-Yakoub,Kevin Wingeier,Ulrike Held et al.
Ilona Stefanos-Yakoub et al.
In addition to the primary aim of seizure freedom, a key secondary aim of pediatric epilepsy surgery is to stabilize and, potentially, optimize cognitive development. Although the efficacy of surgical treatment for seizure control has been ...
Transmembrane α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor regulatory protein expression during the development of absence seizures in genetic absence epilepsy rats from Strasbourg [0.03%]
淀粉样脑回炎小鼠海马中神经胶质细胞来源的细胞因子白细胞介素12表达变化及意义
Pablo M Casillas-Espinosa,Runxuan Lin,Rui Li et al.
Pablo M Casillas-Espinosa et al.
The transmembrane α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) regulatory proteins (TARPs), γ2 (stargazin), γ3, γ4, γ5, γ7, and γ8, are a family of proteins that regulate AMPAR trafficking, expression, and bi...
Temporal relationship between levetiracetam nonadherence and breakthrough seizures in a preclinical model of temporal lobe epilepsy [0.03%]
氨己烯酸不依从与临床上颞叶癫痫发作之间的时序关系模型研究
Michelle Guignet,Jonathan Vuong,Alejandra Martinez et al.
Michelle Guignet et al.
Objective: Poor medication adherence remains a concern for individuals managing their epilepsy with antiseizure medicines (ASMs); however, ethical concerns around withholding medication make it impossible to study the cau...
Long-term physical and psychiatric morbidities and mortality of untreated, deferred, and immediately treated epilepsy [0.03%]
未治、缓治和即刻治疗的癫痫患者的长期躯体疾病、精神障碍和死亡风险
Tianrui Ren,Yingtong Li,Michael Burgess et al.
Tianrui Ren et al.
Objective: In Australia, 30% of newly diagnosed epilepsy patients were not immediately treated at diagnosis. We explored health outcomes between patients receiving immediate, deferred, or no treatment, and compared them t...
The extent of cytochrome P450 3A induction by antiseizure medications: A systematic review and network meta-analysis [0.03%]
抗癫痫药物诱导细胞色素P450 3A的程度：系统评价和网络meta分析
Hagar Cohen,Ghadeer Mahajna,Tomer Ben-Shushan et al.
Hagar Cohen et al.
Objective: Antiseizure medications (ASMs) are commonly categorized as enzyme-inducers and non-enzyme-inducers based on their propensity to enhance the metabolism of concomitantly administered drugs. This systematic review...
Meta-Analysis
Epilepsia. 2024 Feb;65(2):445-455. DOI:10.1111/epi.17822 2024
Kathryn Nichol,Ryan Verner,Charles Gordon et al.
Kathryn Nichol et al.
Maxime O Baud,Christian Rummel
Maxime O Baud
Interaction of interictal epileptiform activity with sleep spindles is associated with cognitive deficits and adverse surgical outcome in pediatric focal epilepsy [0.03%]
儿童局灶性癫痫发作间期癫痫样活动与睡眠纺锤波的相互作用与认知缺陷和不利手术结果相关
Han Yu,Woojoong Kim,David K Park et al.
Han Yu et al.
Objective: Temporal coordination between oscillations enables intercortical communication and is implicated in cognition. Focal epileptic activity can affect distributed neural networks and interfere with these interactio...
Andrew Knight,Tilo Gschwind,Peter Galer et al.
Andrew Knight et al.
Artificial intelligence (AI) allows data analysis and integration at an unprecedented granularity and scale. Here we review the technological advances, challenges, and future perspectives of using AI for electro-clinical phenotyping of anim...