Optimizing responsive neurostimulation targeting based on interictal high-frequency oscillations and phase-amplitude coupling [0.03%]
基于间期高频振荡和相幅耦合的响应式神经刺激靶点优化
Sotaro Kanai,Atsuro Daida,Yipeng Zhang et al.
Sotaro Kanai et al.
Objective: This study was undertaken to determine whether interictal high-frequency oscillations (HFOs) and phase-amplitude coupling (PAC) can serve as spatial biomarkers on intracranial electroencephalography (iEEG) to g...
Value of ultra-high-field MRI in patients with drug-resistant focal epilepsy and negative 3T MRI (EpiUltraStudy): Diagnostic gain of 7T structural analysis [0.03%]
高场磁共振(7特斯拉)检查在药物难治性局灶性癫痫患者中的诊断价值：3T结构检查阴性的患者的诊断增益(EpiUltraStudy研究)
Rick H G J van Lanen,Daniel Uher,Christianne M C Hoeberigs et al.
Rick H G J van Lanen et al.
Objective: Resective epilepsy surgery is an evidence-based treatment option for patients with focal drug-resistant epilepsy (DRE). Seizure outcome after surgery is largely dependent on detection and delineation of an epil...
Paroxysmal slow wave events as a diagnostic biomarker for epilepsy: Lessons from rural Zambia [0.03%]
阵发性慢波事件作为诊断癫痫生物标志物的价值：来自赞比亚农村地区的启示
Andrew Malunga,Sina Lash,Alaa Abu-Ahmad et al.
Andrew Malunga et al.
Objective: Epilepsy affects more than 50 million people globally, with low- and middle-income countries (LMICs) bearing the greatest burden due to limited medical resources and stigma. Electroencephalography (EEG) is a co...
The interacting etiologies of hippocampal sclerosis in epilepsy: A scoping review [0.03%]
与癫痫相关的海马硬化症的相互作用病因学：系统综述
Boris Deleu,Jules Jeuris,Wim Van Paesschen
Boris Deleu
According to the International League Against Epilepsy classification, mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) is considered an epilepsy syndrome. Several etiologies may precede HS, but there is little overview in...
Review
Epilepsia. 2025 Oct 17. DOI:10.1111/epi.18676 2025
Rigorous evaluation of five models for e-diary-only seizure forecasting: Retrospective and prospective datasets do not outperform the Napkin method [0.03%]
五种电子日记癫痫预测模型的严格评估：回顾性和前瞻性数据集无法超越简便方法
Chi-Yuan Chang,Robert Moss,M Brandon Westover et al.
Chi-Yuan Chang et al.
Objective: Seizure forecasting using e-diaries may help patients with seizures to organize their daily life. Until now, most methods were not rigorously tested against a strict standard. This study aims to assess whether ...
Normalization of deviance in neuromodulation for epilepsy [0.03%]
癫痫神经调控中的特异归因偏差现象Normalization of deviance在神经调控治疗癫痫中的体现
Karim Mithani,George M Ibrahim
Karim Mithani
The rapid expansion of neuromodulation therapies for drug resistant epilepsy has introduced a growing risk of normalization of deviance (NoD). This occurs when incremental deviations from established procedures are iteratively reinterpreted...
Spanish translation, adaptation, and validation of the Epilepsy Surgery Satisfaction Questionnaire-19 [0.03%]
癫痫手术满意度问卷19项的西班牙语版翻译、修订及验证
Elena Fonseca,Alejandro Thomson,Mario Alonso et al.
Elena Fonseca et al.
Objective: The effectiveness of surgery in drug-resistant epilepsies is often focused exclusively on seizure control. The Epilepsy Surgery Satisfaction Questionnaire-19 (ESSQ_19), developed in 2020, is a reliable tool for...
Association between local gray matter volume differences and stereo-electroencephalography-defined epileptogenicity [0.03%]
与立体脑电图定义的致痫性相关的局部灰质体积差异
Jacob Bunyamin,Benjamin Sinclair,Thanomporn Wittayacharoenpong et al.
Jacob Bunyamin et al.
Objective: The yield of voxel-based gray matter volume (GMV) quantification to identify the epileptogenic zone (EZ) remained moderate, which may be due to the choice of "ground truth." We explored whether GMV differences ...
Seizure outcomes in persons with autism spectrum disorder undergoing epilepsy surgery: A systematic review and meta-analysis [0.03%]
自闭症谱系障碍患者接受癫痫手术后的发作结局：系统评价和meta分析
Varun R Subramaniam,Jonathan Goldstein,Ali Rafati et al.
Varun R Subramaniam et al.
Objectives: Autism spectrum disorder (ASD) and epilepsy commonly co-occur. Surgical interventions are viable treatment options for individuals with drug-resistant epilepsy. However, past research in patients with ASD and ...
Nanoparticle-encapsulated neuropeptide Y provides robust seizure protection in SCN1A-derived epilepsy [0.03%]
基于SCN1A基因的小分子纳米药物用于难治性癫痫治疗研究进展
Samantha L Reed,Lauren M Aiani,Eesha Faiz et al.
Samantha L Reed et al.
Objective: Neuropeptides have garnered great interest as potential treatments for epilepsy due to their impact on neuronal excitability through modulation of ion channels and neurotransmitter receptor activity. Neuropepti...