Absence seizures and sleep-wake abnormalities in a rat model of GRIN2B neurodevelopmental disorder [0.03%]
GRIN2B神经发育障碍大鼠模型中的失神发作和睡眠-觉醒异常
Katerina Hristova,Melissa C M Fasol,Niamh McLaughlin et al.
Katerina Hristova et al.
Objective: Pathogenic mutations in GRIN2B are an important cause of severe neurodevelopmental disorders resulting in epilepsy, autism, and intellectual disability. GRIN2B encodes the GluN2B subunit of N-methyl-d-aspartate...
Peri-ictal imaging abnormalities in non-convulsive status epilepticus: A systematic review and meta-analysis comparing magnetic resonance imaging and computed tomography perfusion [0.03%]
非惊厥持续状态的围发作期影像异常：系统评价和磁共振成像与计算机断层扫描灌注的Meta分析
Pilar Bosque-Varela,Giorgi Kuchukhidze,Wiebke Hahn et al.
Pilar Bosque-Varela et al.
Objective: To assess and compare the detection rates of peri-ictal abnormalities using magnetic resonance imaging (MRI) and computed tomography perfusion (CTP) in patients with non-convulsive status epilepticus (NCSE). ...
Predictive power of phase 1 studies for the identification of seizure onset zone in phase 2 in a pediatric epilepsy cohort [0.03%]
一项儿童癫痫队列中I期研究对II期发作起始区识别的预测能力
Kalman Katlowitz,Anthony Allam,Nealen Laxpati et al.
Kalman Katlowitz et al.
Objective: Surgical outcomes in the management drug-resistant epilepsy (DRE) rely heavily on proper identification of the seizure onset zone (SOZ). Stereo-electroencephalography (sEEG) can be used to localize SOZs but mus...
Peripheral blood mononuclear cell secretome from patients with autoimmune encephalitis promotes seizures in vitro [0.03%]
自身免疫性脑炎患者外周血单核细胞分泌组促进体外癫痫发作
Sara Prevosti,Alessio Passalacqua,Maria Cristina Regondi et al.
Sara Prevosti et al.
Objective: Autoimmune encephalitis (AE) is characterized by inflammatory processes in the central nervous system and frequently presents with seizures. Even though an ictogenic potential has been shown for some antibodies...
Differential outcomes in familial and sporadic SCN8A self-limited infantile epilepsies: Insights from a large international registry [0.03%]
SCN8A自限性婴儿癫痫在家族性和散发性病例中的不同临床结局：一项国际大型注册研究的见解
Francesca Furia,Sopio Gverdtsiteli,Wibke Janzarik et al.
Francesca Furia et al.
Epilepsy as a dynamic disease: Toward actionable, individualized seizure risk prediction [0.03%]
癫痫作为动态疾病：迈向可操作的、个体化的发作风险预测
Kai Michael Schubert,Anthony G Marson,Eugen Trinka et al.
Kai Michael Schubert et al.
The current definition of epilepsy allows diagnosis after a single unprovoked seizure if the estimated 10-year recurrence risk is ≥60%. While this framework is grounded in epidemiological evidence, it does not align with the shorter time h...
Real-world comparison of first-line antiseizure monotherapy and the role of age at treatment initiation in newly diagnosed childhood epilepsy: A cohort study from a tertiary center [0.03%]
新诊断的儿童癫痫一线单药治疗的现实世界比较及初始治疗年龄的作用：来自三级医疗中心的一例队列研究
Ningshan Li,Huiting Zhang,Chaoran Yang et al.
Ningshan Li et al.
Objective: This study was undertaken to evaluate the real-world effectiveness and tolerability of first-line antiseizure medication (ASM) monotherapy in children with newly diagnosed epilepsy, focusing on comparative outc...
Folate transfer across the placenta during late pregnancy in women with epilepsy: A cross-sectional, two-center study [0.03%]
癫痫孕妇晚期妊娠胎盘叶酸转运：一项横断面、两中心研究
Erez Berman,Gali Pariente,Natalia Erenburg et al.
Erez Berman et al.
Objective: In women with epilepsy who are treated with antiseizure medications (ASMs), folate concentrations in maternal serum may not be a good indicator of fetal folate supply, because ASMs can interfere with folate han...
Treatment of epilepsy using newer antiseizure medications: A retrospective cohort study of prescription patterns in Sweden 2013-2022 [0.03%]
2013年至2022年瑞典使用新型抗癫痫药物治疗癫痫的回顾性队列研究：处方模式
Kristian Bolin,Patric Berling,Torbjörn Tomson
Kristian Bolin
Objective: This study aimed to analyze the choice of newly introduced antiseizure medications (ASMs; brivaracetam, cannabidiol, cenobamate, fenfluramine, and perampanel) by age and sex, and the use of these ASMs in relati...
Reliability and diagnostic accuracy of home video recording in differentiating sleep-related hypermotor epilepsy from disorders of arousal [0.03%]
家庭视频记录在区分睡眠相关过度运动癫痫和觉醒障碍中的可靠性和诊断准确性
Laura Licchetta,Greta Mainieri,Giuseppe Loddo et al.
Laura Licchetta et al.
Objective: This study evaluates the interobserver reliability (IR) and diagnostic accuracy of home video in distinguishing sleep-related hypermotor epilepsy (SHE) from disorders of arousal (DoA) among neurologists with va...