Development and characterization of an autoresuscitation test for preclinical SUDEP models [0.03%]
用于术前SUDEP模型的自动复苏试验的开发与表征
Shruthi H Iyer,Jillian E Hinman,Samantha B Draves et al.
Shruthi H Iyer et al.
The rate of sudden unexpected death in epilepsy (SUDEP) is ~1 per 1000 patients each year. Terminal events reportedly involve repeated and prolonged apnea, suggesting a failure to autoresuscitate. To better understand the mechanisms and ide...
Common network related to hyperkinetic seizures revealed by functional lesion network mapping [0.03%]
功能病变网络映射发现与阵发性运动障碍相关的共通脑网络
Bowen Yang,Chen Yao,Jinping Xu et al.
Bowen Yang et al.
Objective: This study aims to determine whether the anatomically heterogeneous lesions that cause hyperkinetic seizures (HKS) are connected to a common functional network. ...
How accurate are witnesses of first suspected seizures in recalling semiology at clinically relevant timepoints? A UK experimental study with a pilot intervention [0.03%]
首次疑似癫痫发作的目击者在临床相关时间点上回忆症状学的准确性？一项英国实验研究及其试点干预措施
Adam J Noble,Steven Lane,Paul New et al.
Adam J Noble et al.
Objective: A key diagnostic challenge at "first seizure" clinic appointments is determining whether the reported event was epileptic. Witness accounts are often critical, yet such appointments typically occur weeks after ...
A critical review of high-frequency activity for functional mapping in SEEG [0.03%]
脑电图功能定位中高频活动的关键评论文章
Parveen Sagar,Matt Hudson,Genevieve Rayner et al.
Parveen Sagar et al.
Mapping functional brain networks is a critical component of stereo-electroencephalography (SEEG) evaluations. Although direct cortical stimulation (DCS) is the clinical gold standard, it has important limitations-particularly in mapping di...
Review
Epilepsia. 2025 Sep 5. DOI:10.1111/epi.18619 2025
Incidence, mortality, and management of status epilepticus from 2012 to 2022: An 11-year nationwide study [0.03%]
2012至2022年我国癫痫持续状态的发病、死亡及诊疗特征：基于全国性大样本的11年回顾式分析
Quentin Calonge,Aurélie Hanin,Edouard Januel et al.
Quentin Calonge et al.
Objective: Recent data on status epilepticus (SE) incidence and mortality remain limited, despite the 2015 revision of its definition by the International League Against Epilepsy. The impact of the COVID-19 pandemic also ...
Deciphering SCN2A: A comprehensive review of rodent models of Scn2a dysfunction [0.03%]
SCN2A的解读：Scn2a功能异常啮齿动物模型综述
Katelin E J Scott,Maria Fernanda Hermosillo Arrieta,Aislinn J Williams
Katelin E J Scott
SCN2A encodes for the alpha subunit of the voltage-gated sodium channel NaV1.2, which is involved in action potential initiation and backpropagation in excitatory neurons. Currently, it is one of the highest monogenetic risk factors for bot...
Review
Epilepsia. 2025 Aug 30. DOI:10.1111/epi.18615 2025
Functional/dissociative seizures: Proposal for a new diagnostic label and definition by the ILAE task force [0.03%]
发作性疾病/分离性癫痫发作：ILAE工作组的新诊断分类及定义建议
Coraline Hingray,Stoyan Popkirov,Kasia Kozlowska et al.
Coraline Hingray et al.
The acceptability and validity of the term "psychogenic nonepileptic seizures" (PNES) have been questioned. Currently, numerous alternative terms, such as "conversion," "dissociative," "functional," "attacks," and "events," are used in both...
Presence of interictal epileptiform EEG discharges implies increased risk of recurrence after the first unprovoked seizure: Report of the International League Against Epilepsy and International Federation of Clinical Neurophysiology [0.03%]
国际抗癫痫联盟和国际临床神经生理学联合会关于首次不明原因发作后出现间歇期痫样放电的复发风险增加的报告
Betül Baykan,John Dunne,Samuel Wiebe et al.
Betül Baykan et al.
Objective: A joint International Federation of Clinical Neurophysiology-International League Against Epilepsy (IFCN-ILAE) Taskforce was created to explore the published evidence for initial EEG recordings in the evaluatio...
Exploratory study of peripheral immune changes associated with diffusion MRI multi-compartment model in temporal lobe epilepsy [0.03%]
基于扩散磁共振多室模型的颞叶癫痫外周免疫变化的相关性探索性研究
Jerzy P Szaflarski,Rodolphe Nenert,Huixian Hong et al.
Jerzy P Szaflarski et al.
Objective: Studies in temporal lobe epilepsy (TLE) have shown that focal inflammation is a key contributor to seizure initiation and maintenance. However, most in vivo studies to date have focused on positron emission tom...
Association between enlarged perivascular space (ePVS) density and stereo-electroencephalography (SEEG) biomarkers of epileptogenicity [0.03%]
扩大的血管周围空间(ePVS)密度与癫痫发生生物标志物的关系
Jacob Bunyamin,Benjamin Sinclair,Thanomporn Wittayacharoenpong et al.
Jacob Bunyamin et al.
Objective: We aim to explore the association between enlarged perivascular space (ePVS) density and stereo-electroencephalography (SEEG) biomarkers of epileptogenicity. ...