Availability and affordability of cannabinoids for epilepsy treatment across different geographic settings-A survey from the ILAE Plant-Based Therapy Task Force [0.03%]
癫痫治疗中大麻素的可及性和可负担性——来自ILAE植物药治疗工作组的调查研究报告
Kollencheri Puthenveettil Vinayan,Ali Akbar Asadi-Pooya,Aruna Setumadhava Jyotsna et al.
Kollencheri Puthenveettil Vinayan et al.
Guilherme L Fialho,Ramsés Miotto,Katia Lin
Guilherme L Fialho
Beyond the spike: Functional (dissociative) seizures as a key to holistic attitudes in seizure disorders [0.03%]
超越单纯症状诊断：功能性（分离性）癫痫发作与全面考虑的癫痫态度之间的关系
Mahinda Yogarajah,Barbara Dworetzky,Josemir W Sander et al.
Mahinda Yogarajah et al.
Epileptologists can improve outcomes through follow-up and coordination of care for patients with functional seizures. Epileptic and functional seizures share some mechanistic overlap involving interoceptive, emotional, and stress dysregula...
Artificial intelligence-driven closed-loop devices in sudden unexpected death in epilepsy prediction and prevention: Insights from persons with epilepsy and caregivers [0.03%]
人工智能驱动的突然意外癫痫死亡预测和预防闭环装置：来自癫痫患者和照料者的见解
João Ferreira,Miguel França,Mariana Cardoso Regalo et al.
João Ferreira et al.
Objective: The absence of strategies for predicting and preventing sudden unexpected death in epilepsy (SUDEP) is intertwined with the lack of studies measuring users' attitudes toward potential innovative interventions. ...
Synaptic ultrastructural alterations in human focal cortical dysplasia: Insights from volume electron microscopy [0.03%]
人局部皮质发育不良的突触超微结构改变：来自体积电镜的启示
Gyu Hyun Kim,Na-Young Seo,Seung-Ki Kim et al.
Gyu Hyun Kim et al.
Objective: Focal cortical dysplasia (FCD) is a developmental malformation of the cerebral cortex and a leading cause of drug-resistant epilepsy in children and young adults. Disruption of the excitation-inhibition (E-I) b...
Targeting interictal low-entropy zones during epilepsy surgery predicts successful outcomes in pediatric drug-resistant epilepsy [0.03%]
儿童难治性癫痫手术期间针对间歇期低熵区可预测良好预后
Navaneethakrishna Makaram,Matthew Pesce,Melissa Tsuboyama et al.
Navaneethakrishna Makaram et al.
Objective: Approximately 40% of children undergoing epilepsy surgery have postoperative seizures, underscoring the need for enhanced estimators of the epileptogenic zone (EZ). We hypothesize that visually imperceptible lo...
Peri-ictal respiratory dysfunction: Expanding the association between mTOR pathway disorders and ictal central apnea [0.03%]
与mTOR通路障碍和痫性中枢性呼吸暂停关联的扩大：围发作期呼吸功能障碍
Margherita Burani,Giada Giovannini,Niccolò Orlandi et al.
Margherita Burani et al.
Among the etiologies of focal epilepsy, mutations of the GATOR1 complex genes-comprising NPRL3, NPRL2, and DEPDC5-are known to result in overactivation of mTORC1. A recent study highlighted an association between ictal and postictal central...
Effects of cell therapy on seizures in animal models of epilepsy: Systematic review and meta-analysis [0.03%]
细胞治疗在癫痫动物模型中对抽搐影响的系统评价和 meta 分析
Afaf S Altalhi,Muhammad S Javaid,Nigel C Jones et al.
Afaf S Altalhi et al.
This study was undertaken to systematically evaluate the efficacy of cell therapy in reducing seizures in animal models of chronic epilepsy. Three databases, Ovid MEDLINE, Ovid Embase, and Web of Science, were searched using predetermined e...
Review
Epilepsia. 2025 Sep 19. DOI:10.1111/epi.18633 2025
Extracellular vesicle microRNAs are biomarkers of focal epilepsy but not epilepsy-related respiratory dysfunction [0.03%]
外泌体微RNA可作为局灶性癫痫的生物标志物而非癫痫相关呼吸功能障碍的生物标志物
Sylvain Rheims,Hayet Kouchi,Florence Busato et al.
Sylvain Rheims et al.
Objective: This study was undertaken to evaluate the diagnostic value of a set of preselected candidate microRNAs (miRNAs) extracted from plasma-based extracellular vesicles (EVs) to identify patients with seizure-related...
Decreased cholinergic neuronal firing in a mouse model of temporal lobe seizures with impaired consciousness [0.03%]
在意识受损的颞叶癫痫小鼠模型中胆碱能神经元放电减少
Shixin Liu,Patrick Paszkowski,Jiayin Qu et al.
Shixin Liu et al.
Objective: Impaired consciousness during seizures significantly impacts the quality of life for individuals with epilepsy, and recent research has introduced the network inhibition hypothesis, suggesting that impaired con...