Pharmacokinetic variability and complex two-way interactions with cenobamate in patients with refractory epilepsy [0.03%]
Cecilie Johannessen Landmark,Heba Belkilani,Lilyana Awad et al.
Cecilie Johannessen Landmark et al.
Objectives: Cenobamate (CNB) is a new antiseizure medication (ASM) for add-on therapy in adults with refractory epilepsy. The purpose of this study was to investigate the pharmacokinetic variability of CNB and extent of i...
Pentanucleotide repeat instability and transmission in benign adult familial myoclonic epilepsy types 1, 4, and 8 [0.03%]
Supphakorn Rakwongkhachon,Monnat Pongpanich,Chalurmpon Srichomthong et al.
Supphakorn Rakwongkhachon et al.
Objective: Benign adult familial myoclonic epilepsy (BAFME) is a rare autosomal dominant disorder characterized by tremor and myoclonic seizures. To date, seven genetic subtypes have been identified, all caused by noncodi...
Clinical characteristics and surgical outcomes of Rasmussen encephalitis: A retrospective dual-center cohort study [0.03%]
Yilin Liu,Kun Lv,Hongru Guo et al.
Yilin Liu et al.
Objective: Rasmussen encephalitis (RE) is a rare progressive disorder causing drug-resistant epilepsy. Hemispheric surgery is an established treatment, but comprehensive data on postoperative seizure, motor, and cognitive...
Tissue oxygenation dynamics during transition from seizure to spreading depolarization in rat brain [0.03%]
Jiayang Liu,Bruce J Gluckman
Jiayang Liu
Objective: Spreading depolarization (SD) is a phenomenon underlying various neurological conditions, including epilepsy. Researchers have suspected that local tissue oxygenation breakdown induces spontaneous SD. In this s...
Surgical treatment of epilepsy in polymicrogyria: A subject-level meta-analysis and decision-making framework [0.03%]
Luca Bosisio,Carolina Viglietti,Alessandro Consales et al.
Luca Bosisio et al.
Objective: Polymicrogyria (PMG) presents a complex challenge in epilepsy surgery. The optimal surgical strategy and extent of resection, from hemispheric to more limited approaches, remain debated. We aimed to summarize s...
Barbara Tettenborn,Georgia Ramantani,Dominique Flügel et al.
Barbara Tettenborn et al.
Women with epilepsy (WWE) encounter distinct and evolving challenges across the lifespan that require clinical management extending beyond seizure control alone. Although awareness of sex-specific aspects of epilepsy has increased, importan...
Review
Epilepsia. 2026 Mar 19. DOI:10.1002/epi.70202 2026
Agreement and 2-year trajectories of youth- and parent-reported health-related quality of life in youth with epilepsy treated with surgery vs medical therapy [0.03%]
Mary Lou Smith,Klajdi Puka,Elysa Widjaja
Mary Lou Smith
Objective: This cohort study examined the agreement between youth- and parent-reported health-related quality of life (HRQOL) of children treated with epilepsy surgery compared to medical therapy. A second aim was to eval...
Response: An etiology-driven framework for status epilepticus and ictal-interictal continuum [0.03%]
Pilar Bosque-Varela,Eugen Trinka,Giorgi Kuchukhidze
Pilar Bosque-Varela
Simona Lattanzi
Simona Lattanzi