A multisociety consensus statement on a new common definition and diagnostic criteria for PSVD or NCPF [0.03%]
慢加重症肝炎诊断国际标准的专家共识
Virginia Hernandez-Gea,Valerie Paradis,Maha Guindi et al.
Virginia Hernandez-Gea et al.
Noncirrhotic portal hypertension has historically been described using heterogeneous and region-specific terminology-such as idiopathic portal hypertension (IPH), noncirrhotic portal fibrosis (NCPF), obliterative portal venopathy, and nodul...
CD4+ T cells promote fibrosis during metabolic dysfunction-associated steatohepatitis [0.03%]
CD4⁺T细胞通过促进代谢紊乱相关酒精性肝炎中的纤维化发挥作用
Lucía Valenzuela-Pérez,Hyun Se Kim Lee,Rachel L Bayer et al.
Lucía Valenzuela-Pérez et al.
Background and aims: Unresolved inflammation and fibrosis are defining features of metabolic dysfunction-associated steatohepatitis (MASH), a progressive form of steatotic liver disease that can advance to cirrhosis and h...
Definition, diagnosis, and treatment of primary biliary cholangitis - autoimmune hepatitis (PBC-AIH) variant: An international expert delphi consensus [0.03%]
原发性胆汁性胆管炎-自身免疫性肝炎(PBC-AIH)变异型的定义、诊断和治疗：国际专家共识德尔菲调查结果
Alessio Gerussi,Marcial Sebode,Eugenia Nofit et al.
Alessio Gerussi et al.
Background and aims: Heterogeneity in the definition, diagnosis and treatment of primary biliary cholangitis-autoimmune hepatitis (PBC-AIH) is present in guidelines and daily practice. This initiative aimed to establish e...
Consistent efficacy of efruxifermin across PNPLA3 genotypes in phase 2b trials in MASH [0.03%]
针对MASH患者中不同PNPLA3基因型的2b期临床试验显示Efruxifermin的一致有效性的研究
Naga Chalasani,Erik J Tillman,Sonja K Billes et al.
Naga Chalasani et al.
Diabetes, male sex, low levels of HBsAg, HDV RNA and ALT predict spontaneous HDV suppression in chronic hepatitis D [0.03%]
糖尿病、男性性别、HBsAg偏低水平、HDV RNA和ALT可预测慢性乙肝合并丁肝的自发性抑制作用
Habiba Kamal,Ganbolor Jargalsaikhan,Sanjaasuren Enkhtaivan et al.
Habiba Kamal et al.
Background aims: Persistent HDV replication is associated with severe liver disease, yet predictors of spontaneous HDV RNA suppression remain poorly defined. We assessed the incidence and predictors of spontaneous HDV sup...
Non-contrast abbreviated MRI demonstrates superior diagnostic accuracy compared to ultrasound for hepatocellular carcinoma detection: Interim results from a prospective surveillance trial [0.03%]
无对比剂快速MRI技术用于肝癌筛查的诊断价值优于超声：前瞻性研究中期结果分析
Pankaj Gupta,Shravya Singh,Ajay Gulati et al.
Pankaj Gupta et al.
Aim: To prospectively evaluate the diagnostic performance of a rapid abbreviated non-contrast MRI (AMRI) protocol compared to ultrasound (US) for hepatocellular carcinoma (HCC) surveillance in a high-risk population with ...
Palmitoylation-mediated exosomal trafficking of nuclear protein NAT10 potentiates liver fibrosis in MASH [0.03%]
棕榈酰化介导的核蛋白NAT10囊泡运输促进MASHH小鼠模型肝纤维化进展
Yadi Wang,Liangliang Wu,Zhaozhi Li et al.
Yadi Wang et al.
Background aims: Liver fibrosis is the principal histological determinant of mortality in metabolic dysfunction-associated steatohepatitis (MASH), yet the mechanisms driving progression from steatosis to fibrosis remain i...
Buying time: Therapeutic plasma exchange as a bridge to transplant in acute-on-chronic liver failure [0.03%]
买时间：在急性重型肝炎治疗中血浆置换疗法作为肝脏移植的过渡治疗方法
Christina C Lindenmeyer
Christina C Lindenmeyer
Optimizing bevacizumab exposure in atezolizumab-based therapy for unresectable hepatocellular carcinoma: A nationwide real-world study [0.03%]
贝伐珠单抗优化剂量联合阿特朱单抗治疗不可切除肝细胞癌的全国真实世界研究
Kaho Aoe,Toshifumi Tada,Atsushi Hiraoka et al.
Kaho Aoe et al.
Background aims: Atezolizumab plus bevacizumab (Atezo/Bev) is administered for unresectable hepatocellular carcinoma (HCC), with bevacizumab dosed by body weight, which may not adequately reflect body composition. This st...