David Engelhardt,Amber Marean,David McKean et al.
David Engelhardt et al.
Cilia play a key role in the regulation of signaling pathways required for embryonic development, including the proper formation of the neural tube, the precursor to the brain and spinal cord. Forward genetic screens were used to generate m...
Nicholas W Plummer,Kathleen G Smith,Patricia Jensen
Nicholas W Plummer
HAND2 is a basic helix-loop-helix transcription factor with diverse functions during development. To facilitate the investigation of genetic and functional diversity among Hand2-expressing cells in the mouse, we have generated Hand2Dre, a k...
Ectopic expression in commonly used transgenic Drosophila GAL4 driver lines [0.03%]
常用果蝇GAL4转基因品系的异位表达
Mattias Winant,Kurt Buhler,Patrick Callaerts
Mattias Winant
Transgenic tools such as the GAL4/UAS system in Drosophila have been used extensively to induce spatiotemporally controlled changes in gene expression and tissue-specific expression of a range of transgenes. We previously discovered unexpec...
Following the p63/Keratin5 basal cells in the sensory and non-sensory epithelia of the vomeronasal organ [0.03%]
沿着犁鼻器感觉上皮和非感觉上皮中的p63/Keratin5基底细胞分布特点观察其动态变化规律
Noah M LeFever,Raghu Ram Katreddi,Nikki M Dolphin et al.
Noah M LeFever et al.
The vomeronasal organ (VNO) is a part of the accessory olfactory system, which detects pheromones and chemical factors that trigger a spectrum of sexual and social behaviors. The vomeronasal epithelium (VNE) shares several features with the...
Activity-dependent formation of the topographic map and the critical period in the development of mammalian olfactory system [0.03%]
依赖活动的拓扑图形成及关键时期在哺乳动物嗅觉系统发育中的作用
Ai Fang,C Ron Yu
Ai Fang
Neural activity influences every aspect of nervous system development. In olfactory systems, sensory neurons expressing the same odorant receptor project their axons to stereotypically positioned glomeruli, forming a spatial map of odorant ...
Insertion of a neomycin selection cassette in the Amigo1 locus alters gene expression in the olfactory epithelium leading to region-specific defects in olfactory receptor neuron development [0.03%]
新霉素选择框嵌入Amigo1基因座影响嗅觉上皮的基因表达并导致感觉神经元区域特异性发育缺陷
Reesha Raja,Emilie Dumontier,Alina Phen et al.
Reesha Raja et al.
During development of the nervous system, neurons connect to one another in a precisely organized manner. Sensory systems provide a good example of this organization, whereby the composition of the outside world is represented in the brain ...
Type 2 vomeronasal receptor-A4 subfamily: Potential predator sensors in mice [0.03%]
第二类犁鼻受体A4亚家族：小鼠潜在的捕食者传感器
Andrea Rocha,Quynh Anh Thi Nguyen,Sachiko Haga-Yamanaka
Andrea Rocha
Sensory signals detected by olfactory sensory organs are critical regulators of animal behavior. An accessory olfactory organ, the vomeronasal organ, detects cues from other animals and plays a pivotal role in intra- and inter-species inter...
The biological characteristics of chicken embryo mesenchymal stem cells isolated from chorioallantoic membrane [0.03%]
鸡尿囊膜间充质干细胞的生物学特性研究
Yue Wu,Yunan Wang,Weijun Gan et al.
Yue Wu et al.
Mesenchymal stem cells (MSCs) derived from fetal membranes (FMs) have the potential to exhibit immunosuppression, improve blood flow, and increase capillary density during transplantation. In the field of medicine, opening up new avenues fo...
Nusrath Yusuf,Kevin Monahan
Nusrath Yusuf
The mammalian sense of smell relies upon a vast array of receptor proteins to detect odorant compounds present in the environment. The proper deployment of these receptor proteins in olfactory sensory neurons is orchestrated by a suite of e...
Signaling mechanisms underlying activity-dependent integration of adult-born neurons in the mouse olfactory bulb [0.03%]
小鼠嗅球成年神经元生成依赖活动的整合机制
Suyang Bao,Juan M Romero,Benjamin D W Belfort et al.
Suyang Bao et al.
Adult neurogenesis has fascinated the field of neuroscience for decades given the prospects of harnessing mechanisms that facilitate the rewiring and/or replacement of adult brain tissue. The subgranular zone of the hippocampus and the subv...