Identification of a Novel nkx2.3 Transgenic Reporter Specifically Visualizing Craniofacial Muscle Development in Zebrafish [0.03%]
斑马鱼新型nkx2.3转基因报告基因系的鉴定及其特异性揭示头面部肌肉发育的作用
Yucheol Choe,Haewon Jeon,Sil Jin et al.
Yucheol Choe et al.
Transgenic reporters offer valuable opportunities to investigate the genetic and cellular basis of embryonic development in live organisms. While the specificity of transgenic reporters is essential for their effectiveness in developmental ...
An Efficient Method for Neuron-Like Differentiation of SH-SY5Y Neuroblastoma Cells Using Retinoic Acid and Laminin-Rich Extracellular Matrix [0.03%]
视黄酸和含 laminin 富集的细胞外基质诱导SH-SY5Y神经母细胞瘤分化的一种高效方法
Marina Mantellatto Grigoli,Bianca Cruz Pachane,Angelina Maria Fuzer et al.
Marina Mantellatto Grigoli et al.
The human neuroblastoma cell line SH-SY5Y is widely used in vitro as a model due to its ability to acquire neuron-like properties. Conventional differentiation protocols often rely on retinoic acid (RA), which can lead to limited stability ...
Expression of Growth Factor Genes in the Body Wall of the Holothurian Eupentacta fraudatrix During Regenerative Processes [0.03%]
海参Eupentacta fraudatrix再生过程中的体壁生长因子基因表达模式分析
A S Girich
A S Girich
Research into regeneration in sea cucumbers makes a significant contribution to understanding the fundamental mechanisms of this process. However, these studies focus only on the regenerating organs-the intestine and aquapharyngeal bulb. Th...
Generation and Characterization of a Rdh1-iCre Line to Study Uterine Glandular Biology [0.03%]
用于研究子宫腺体生物学的Rdh1-icre系的生成与鉴定
Mana Ohtomo,Shunsuke Takarabe,Takafumi Namiki et al.
Mana Ohtomo et al.
The uterus is an essential organ for fetal development in most mammals. Uterine glands, highly conserved structures in the mammalian uterus, play critical roles in the establishment and maintenance of pregnancy and have been implicated in t...
Divergent Spatiotemporal Expression Patterns of Histone Deacetylases During Mouse Embryonic Tongue, Palate, and Mandible Development [0.03%]
小鼠胚胎舌、腭和下颌发育过程中组蛋白去乙酰化酶的时空表达模式差异
Chubo Yang,Mingxing Wang,Jiaqi Kong et al.
Chubo Yang et al.
Epigenetic regulation is indispensable for embryonic development, yet the specific roles of histone deacetylases (HDACs)-a core family of epigenetic regulatory enzymes-in orchestrating craniofacial morphogenesis remain incompletely elucidat...
Ectopic Bulged Structures in Nkx2-1-KO and FoxE-KO Juveniles of Ciona robusta: Insights Into the Parallel Gene Regulatory System Before the Evolution of Thyroid Follicular Cells [0.03%]
Ci-robr-Nkx2-1和Ci-robr-FoxE敲除刺胞虫的异位膨出结构：探讨甲状腺滤泡细胞进化之前的并行基因调控系统
Hiroki Kawamorita,Mizuki Ito,Yasunori Sasakura et al.
Hiroki Kawamorita et al.
Follicular thyroid cells in vertebrates are considered to have evolved from the endostyle of invertebrate chordates based on the shared features of the concentration of iodine and expression of thyroid-related genes, including Nkx2-1, FoxE,...
Meet Our Editorial Board-Genesis. An Interview With Anna Di Gregorio, New York University, New York, USA [0.03%]
主编访谈-起源篇 安娜·迪格雷戈里奥 华盛顿大学 美国
Paul Trevorrow,Anna Di Gregorio
Paul Trevorrow
Multiplexed Retinoic Acid Signal Reporters for In Vivo and In Vitro Use [0.03%]
用于体内和体外的多路复用视黄酸信号报告基因
Craig Smith,Bianca Black,Ric Broadhurst et al.
Craig Smith et al.
Here we describe the optimisation of a modular, generally applicable and rapid method to make multimerised signaling-molecule reporters for detecting different retinoic acid concentrations. The technical plasmid design allows for the easy e...
Generation and Characterization of Twist1 Acetyl-Mimic and Acetyl-Deficient Mouse Models [0.03%]
Twist1 拟乙酰化和去乙酰化的基因修饰小鼠模型的构建及表征
Mary Elmeniawi,Xiaobin Yu,Samuel Wen et al.
Mary Elmeniawi et al.
TWIST1 encodes a highly conserved basic helix-loop-helix transcription factor essential for embryonic development from Drosophila to humans. TWIST1 activity is regulated by post-translational modifications, including phosphorylation during ...
Phylogenetic Comparison and Splice Site Conservation of the Animal SMNDC1 Gene Family [0.03%]
动物SMNDC1基因家族的系统发生比较及剪接位点的保守性分析
Jing-Wan Zhang,Hong-Mei Wang,Guojun Ouyang et al.
Jing-Wan Zhang et al.
Alternative splicing is a key post-transcriptional process that generates multiple mRNAs from a single pre-mRNA through the coordinated action of the spliceosome and associated splicing factors. SMNDC1 (survival motor neuron domain containi...