Lisa M Mehlmann,Tracy F Uliasz,Siu-Pok Yee et al.
Lisa M Mehlmann et al.
Specific removal of a protein is a key to understanding its function. "Trim-Away" utilizes TRIM21, an antibody receptor and ubiquitin ligase, for acute and specific reduction of proteins. When TRIM21 is expressed in cells, introduction of a...
Cora L Bright,Howard M Bomze,Mantu Bhaumik et al.
Cora L Bright et al.
Armadillo repeat-containing X-linked protein-1 (Armcx1) is a poorly characterized transmembrane protein that regulates mitochondrial transport in neurons. Its overexpression has been shown to induce neurite outgrowth in embryonic neurons an...
Expression and Transcriptional Targets of TGFβ-RII in Paracentrotus lividus Larval Skeletogenesis [0.03%]
海生食人球海胆幼虫骨架发生过程中TGFβ-RII的表达及其转录靶基因
Daniel Goloe,Tsvia Gildor,Smadar Ben-Tabou de-Leon
Daniel Goloe
Organisms from the five kingdoms of life use minerals to harden their tissues and make teeth, shells and skeletons, in the process of biomineralization. The sea urchin larval skeleton is an excellent system to study the biological regulatio...
Two decades on: Special issue on olfaction celebrating Axel and Buck's Nobel Prize [0.03%]
庆贺Axel和Buck的诺贝尔奖：纪念气味研究二十一世纪二十年代特刊
Paolo E Forni,C Ron Yu
Paolo E Forni
Sox21 homeologs autoregulate expression levels to control progression through neurogenesis [0.03%]
Sox21同源物通过自身调节表达水平来控制神经发生进程
Dillon L Damuth,Doreen D Cunningham,Elena M Silva
Dillon L Damuth
The SRY HMG box transcription factor Sox21 plays multiple critical roles in neurogenesis, with its function dependent on concentration and developmental stage. In the allotetraploid Xenopus laevis, there are two homeologs of sox21, namely s...
The influence of olfactory experience on the birthrates of olfactory sensory neurons with specific odorant receptor identities [0.03%]
嗅觉体验对特定气味受体身份的嗅觉感觉神经元出生率的影响
Karlin E Rufenacht,Alexa J Asson,Kawsar Hossain et al.
Karlin E Rufenacht et al.
Olfactory sensory neurons (OSNs) are one of a few neuron types that are generated continuously throughout life in mammals. The persistence of olfactory sensory neurogenesis beyond early development has long been thought to function simply t...
Ai Nakashima,Haruki Takeuchi
Ai Nakashima
The organization of the olfactory glomerular map involves the convergence of olfactory sensory neurons (OSNs) expressing the same odorant receptor (OR) into glomeruli in the olfactory bulb (OB). A remarkable feature of the olfactory glomeru...
CircSCNN1A inhibits the proliferation, migration and invasion of renal cell carcinoma cells by decreasing CLDN8 expression through miR-590-5p [0.03%]
Circular RNA CircSCNN1A通过下调CLDN8抑制肾细胞癌进展的作用及机制研究
Tingting Guo,Wanjuan Xiong,Chong Liu et al.
Tingting Guo et al.
Background: Increasing evidence suggests that circular RNA (circRNA) plays a regulatory role in the progression of renal cell carcinoma (RCC). However, the precise function and underlying mechanism of circSCNN1A in RCC pr...
Dennean S Lippner,Jiang Xu,Siqi Ma et al.
Dennean S Lippner et al.
The vomeronasal organ (VNO) is a specialized chemoreceptive structure in many vertebrates that detects chemical stimuli, mostly pheromones, which often elicit innate behaviors such as mating and aggression. Previous studies in rodents have ...
CRISPR-Cas9 delivery strategies and applications: Review and update [0.03%]
CRISPR-Cas9传递策略与应用：综述及更新
Ali Alizadeh Severi,Bahman Akbari
Ali Alizadeh Severi
Nowadays, a significant part of the investigations carried out in the medical field belong to cancer treatment. Generally, conventional cancer treatments, including chemotherapy, radiotherapy, and surgery, which have been used for a long ti...