Pearls & Oy-sters: Acute Cerebral Occlusion due to Parosteal Osteosarcoma Embolus [0.03%]
珍珠与 oy-sters：Parosteal 骨肉瘤栓子所致急性脑梗死
Jian Wang,Xiao Yang,Li He et al.
Jian Wang et al.
Tumor embolism is a rare cause of acute ischemic stroke. We present a case of a 46-year-old man with a history of distal femoral amputation 11 years prior due to parosteal osteosarcoma who developed acute onset left-sided weakness. Computed...
Case Reports
Neurology. 2026 Aug 11;107(3):e218359. DOI:10.1212/WNL.0000000000218359 2026
Central Obesity and Recurrent Cardiovascular Events in Patients With Obstructive Sleep Apnea: The SAVE Study [0.03%]
中央型肥胖与阻塞性睡眠呼吸暂停患者心血管事件复发的关系：SAVE研究
Shoujiang You,Danni Zheng,Kelly A Loffler et al.
Shoujiang You et al.
Background and objectives: Obesity is a key risk factor underlying both obstructive sleep apnea (OSA) and cardiovascular disease (CVD). The objective of this study was to determine differential strength of associations of...
Randomized Controlled Trial
Neurology. 2026 Aug 11;107(3):e218334. DOI:10.1212/WNL.0000000000218334 2026
Gray Matter Damage and Long-Term Disability, Cognitive Outcome, and Survival in Patients With Multiple Sclerosis [0.03%]
灰质损伤与多发性硬化患者的长期残疾、认知预后和生存率之间的关系
Paolo Preziosa,Alessandro Meani,Nicolò Tedone et al.
Paolo Preziosa et al.
Background and objectives: Gray matter (GM) damage is a key determinant of clinical disability in multiple sclerosis (MS), but its relevance to very long-term outcomes remains insufficiently characterized. We assessed ass...
Convulsions, Palsy, and the Spanish Inquisition: Neurologic Cases in an Overlooked Historical Archive [0.03%]
癫痫、瘫痪与西班牙宗教法庭——一座被忽略的历史档案馆中的神经学案例
Jose-Alberto Palma,Fermin Palma
Jose-Alberto Palma
A largely unrecognized feature of the Spanish Inquisition (1478-1834) was the mandatory medical evaluation of all defendants, generating a vast archive of clinical documentation that remains almost entirely unexplored by historians of neuro...
Association Between Postmortem Pathologic Burden and the Rate of Clinical Progression in Patients With Frontotemporal Lobar Degeneration [0.03%]
frontal temporal变性患者死后病理负担与临床进展速度之间的关系
Rogan G Magee,Sharon X Xie,Daniel T Ohm et al.
Rogan G Magee et al.
Background and objectives: Histopathologic staging of Alzheimer disease has led to validation of imaging techniques that guide diagnosis and treatment. We previously constructed preliminary phases of the sequential progre...
Gary A Ford
Gary A Ford
Multidomain Lifestyle Intervention in Mild Cognitive Impairment: Subgroup Analysis of the SUPERBRAIN-MEET Randomized Trial [0.03%]
轻度认知障碍的多领域生活方式干预：SUPERBRAIN-MEET随机试验的亚组分析
Da Ae Kim,Sun Min Lee,Kyunghwa Sun et al.
Da Ae Kim et al.
Background and objectives: Mild cognitive impairment (MCI) is a high-risk stage for progression to dementia. The SUPERBRAIN-MEET trial previously demonstrated cognitive benefits of a multidomain lifestyle intervention (ML...
Randomized Controlled Trial
Neurology. 2026 Aug 11;107(3):e218297. DOI:10.1212/WNL.0000000000218297 2026
Prospects Are Looking Up for Treatment of Neurogenic Orthostatic Hypotension in Multiple System Atrophy [0.03%]
发作性多灶性脑脊髓炎的治疗前景光明-曲安奈德联合皮质类固醇冲击疗法可改善长期结局
William P Cheshire
William P Cheshire
Exploring Between-Study Heterogeneity in Extended-Window IV Thrombolysis for Acute Ischemic Stroke: A Meta-Analysis of 18 Randomized Controlled Trials [0.03%]
延长溶栓时间窗的静脉组织型纤溶酶原激活剂治疗急性缺血性卒中的异质性：18项随机对照试验的 meta 分析
Mohamed F Doheim,Abdullah M Al-Qudah,Romil Singh et al.
Mohamed F Doheim et al.
Background and objectives: IV thrombolysis (IVT) is the standard-of-care evidence-based treatment of eligible patients with acute ischemic stroke (AIS) within 4.5 hours of symptom onset. Emerging evidence supports its use...
Meta-Analysis
Neurology. 2026 Aug 11;107(3):e218331. DOI:10.1212/WNL.0000000000218331 2026
Rapidly Progressive Alzheimer Disease and Related Dementias as a Phase Transition: Symptom Cascades and Survival Inflection [0.03%]
阿尔茨海默病及相关痴呆症的快速进展作为相变：症状级联和生存拐点
Chao Tang,Jiaxin Yang,Wenqin Luo et al.
Chao Tang et al.
Background and objectives: Rapidly progressive Alzheimer disease and related dementias (rpADRD) is a clinically urgent syndrome characterized by accelerated deterioration. Because it is often confounded by acute etiologie...