Teaching NeuroImage: Cortical DWI Hyperintensity, Cerebellar Atrophy, and Presentation With Prolonged Postictal Hemiparesis Suggest CACNA1A-Related Disorder [0.03%]
教学神经影像:皮层DWI高信号,小脑萎缩和持久的阵挛性半身瘫痪提示CACNA1A相关疾病
Iacopo Chiavacci,Adam Gareth Thomas,Krupa Torne et al.
Iacopo Chiavacci et al.
Clinical Reasoning: A 60-Year-Old Man With Rapidly Progressive Left Hemibody Weakness and Vision Loss [0.03%]
临床思维:一名迅速进展的左半身无力和视力丧失的60岁男性患者的诊治思维
Matthew Rock,Shannon C Shipley,Jessica N Little et al.
Matthew Rock et al.
A 60-year-old man presented with 2 weeks of progressive left-sided weakness, dysarthria, and an incongruous left homonymous hemianopsia, with MRI brain showing a lesion involving the right cerebral peduncle, optic radiation, and dorsal midb...
Case Reports
Neurology. 2025 Jul 22;105(2):e213869. DOI:10.1212/WNL.0000000000213869 2025
Clinical Reasoning: Acute and Progressive Cognitive Decline in a 38-Year-Old Man [0.03%]
临床思维:38岁男性患者急性进行性认知功能障碍的原因是什么?
Lei Wu,Wei Jiang,RongRong Du et al.
Lei Wu et al.
The differential diagnosis of multiple intracranial lesions is often perplexing and highly challenging, especially in the early stages. We present the case of a young man who initially presented with an acute headache and memory decline, wh...
Case Reports
Neurology. 2025 Jul 22;105(2):e213871. DOI:10.1212/WNL.0000000000213871 2025
Cortical Cerebral Microinfarcts in Spontaneous Intracerebral Hemorrhage on 3T and 7T MRI [0.03%]
3T和7T磁共振成像在自发性脑内出血中的皮层脑微梗死灶的作用
Wilmar M T Jolink,Susanne J van Veluw,Doeschka A Ferro et al.
Wilmar M T Jolink et al.
Background and objectives: MRI markers of cerebral small vessel disease (cSVD) in patients with spontaneous intracerebral hemorrhage (sICH) have provided insight in the underlying vascular pathology. Cortical cerebral mic...
Observational Study
Neurology. 2025 Jul 22;105(2):e213642. DOI:10.1212/WNL.0000000000213642 2025
CGRP-Targeted Migraine Therapies in Patients With Vascular Risk Factors or Stroke: A Review [0.03%]
血管风险因素或卒中患者的降钙素基因相关肽靶向偏头痛治疗:一篇综述
Michael Thomas Eller,Katarína Schwarzová,Lena Gufler et al.
Michael Thomas Eller et al.
Calcitonin gene-related peptide (CGRP)-targeted therapies, including monoclonal antibodies (mAbs) and gepants, represent a major advancement in migraine prevention, offering greater efficacy and improved tolerability compared with tradition...
Scratching Beneath the Cortex: Superficial White Matter and Alzheimer Disease [0.03%]
浅析皮层外表:白质和阿尔茨海默病
Mario Tranfa,Tiago Gil Oliveira
Mario Tranfa
Association of Superficial White Matter Microstructure With Cortical Pathology Deposition Across Early Stages of the AD Continuum [0.03%]
阿尔茨海默病早期阶段皮质病理沉积与浅表白质微结构的关联性研究
Shuyue Wang,Fan Zhang,Qingze Zeng et al.
Shuyue Wang et al.
Background and objectives: β-amyloid (Aβ) and tau, 2 prominent pathologies of Alzheimer disease (AD), originate in cortical regions and primarily affect, and even spread along, the white matter tracts directly connected...
Incidence of Diffusion-Weighted Imaging Lesions in Patients With Intracerebral Hemorrhage in the Acute and Subacute Time Periods [0.03%]
急性及亚急性期内血肿周围扩散加权成像异常在脑出血患者中的发生率研究
Martina B Goeldlin,Rosa Küttner,Boudewijn Drop et al.
Martina B Goeldlin et al.
Background and objectives: Diffusion-weighted imaging (DWI) lesions in patients with intracerebral hemorrhage (ICH) are associated with poor outcomes. Knowledge about the underlying pathophysiology is scarce, and it is hy...
Multicenter Study
Neurology. 2025 Jul 22;105(2):e213837. DOI:10.1212/WNL.0000000000213837 2025
Role of Brain Age Gap as a Mediator in the Relationship Between Cognitive Impairment Risk Factors and Cognition [0.03%]
脑年龄差在认知障碍风险因素与认知功能关系中的介导作用
Wei Ying Tan,Xiangyuan Huang,Jiannan Huang et al.
Wei Ying Tan et al.
Background and objectives: Cerebrovascular disease (CeVD) and cognitive impairment risk factors contribute to cognitive decline, but the role of brain age gap (BAG) in mediating this relationship remains unclear, especial...
Exploration of Prolonged Remission and the Natural Course of Cluster Headache: An Interview-Based Cohort Study [0.03%]
关于丛集性头痛长期缓解及自然病程的探索——一项基于访谈的研究
Willemijn Naber,Paulien van Tilborg,Anna Zuidgeest et al.
Willemijn Naber et al.
Background and objectives: The aim of this study was to gain rare insight into prolonged cluster headache (CH) remission by (1) identifying patterns and factors associated with and (2) phenotypical changes before prolonge...