Phenotypic Spectrum in Individuals With Pathogenic GABRG2 Loss- and Gain-of-Function Variants [0.03%]
GABRG2失活和激活型致病变异个体的表型谱系分析
Alessandra Rossi,Susan X N Lin,Nathan L Absalom et al.
Alessandra Rossi et al.
Background and objectives: Variants in the GABRG2 gene encoding the γ2 subunit of the γ-aminobutyric acid type A (GABAA) receptor are associated with a spectrum of epilepsy phenotypes. These range from simple febrile se...
Intracranial Nonstenosing Atherosclerotic Plaques Assessed With Vessel Wall MRI in Patients With Embolic Stroke of Undetermined Source [0.03%]
血管壁MRI评估颅内非狭窄动脉粥样硬化斑块在来源不明的脑栓塞患者中的作用
Federico Mazzacane,Beatrice Del Bello,Elisa Rognone et al.
Federico Mazzacane et al.
Background and objectives: Artery-to-artery embolization from vulnerable intracranial nonstenosing atherosclerotic plaques (vNSPs) has been proposed as a major contributor to embolic stroke of undetermined source (ESUS). ...
Lauren Mamer,Frederick K Korley
Lauren Mamer
Rapid Diagnosis of Intracerebral Hemorrhage in Patients With Acute Stroke by Measuring Prehospital GFAP Levels on a Point-of-Care Device (DETECT) [0.03%]
急性卒中患者发病时通过便携式设备检测胶质纤维酸性蛋白水平以快速诊断脑出血（DETECT）
Love-Preet Kalra,Sabina Zylyftari,Kristaps Blums et al.
Love-Preet Kalra et al.
Background and objectives: The rapid identification of intracerebral hemorrhage (ICH) in patients with symptoms of acute stroke is decisive for prehospital triage and initiation of targeted therapies. Glial fibrillary aci...
Clinical Reasoning: Episodes of Uncontrollable Crying in a 52-Year-Old Man With a Sphenopetroclival Tumor [0.03%]
临床思维：一名52岁蝶旁小脑角区肿瘤患者的阵发性不能自控哭泣发作
Zeynep Özdemir,Stjepana Kovac,Walter Stummer et al.
Zeynep Özdemir et al.
A 52-year-old man presented with progressive gait disturbances. MRI demonstrated a large extra-axial tumor in the cerebellopontine angle compressing the brainstem and resulting in hydrocephalus. While taking the patient's history, episodes ...
Case Reports
Neurology. 2025 Jul 22;105(2):e213847. DOI:10.1212/WNL.0000000000213847 2025
Cross-Sectional and Longitudinal Associations of Neighborhood Disadvantage With Fluid Biomarkers of Neuroinflammation and Neurodegeneration [0.03%]
不利社区环境与脑脊液生物标志物的横断面和纵向关系研究
Marissa A Gogniat,Omair A Khan,Brina Ratangee et al.
Marissa A Gogniat et al.
Background and objectives: Living in a socioeconomically disadvantaged neighborhood has an adverse impact on health outcomes, including increased risk of Alzheimer disease (AD). The biological mechanisms underlying this r...
Larry B Goldstein,Jonathan R Crowe,Anindita Deb et al.
Larry B Goldstein et al.
This statement provides general principles of the American Academy of Neurology's (AAN) approach when invited to provide guidance to policymakers on a variety of types of therapies that may have neurologic treatment benefits, but for which ...
Exploring the Sociobiological Mechanisms of Diseases: A Call to Promote Equity in Brain Health [0.03%]
探究疾病的 sociobiological机制：促进脑健康公平性的呼吁
Salvatore Mazzeo,Maria Salsone
Salvatore Mazzeo
Pearls & Oy-sters: Arterial Wall Enhancements and Rapid Clinical Progression in Noninflammatory Cerebral Amyloid Angiopathy [0.03%]
动脉壁增强和非炎症性脑淀粉样血管病的快速临床进展
João Moura,Vasco Abreu,João Pedro Filipe et al.
João Moura et al.
Cerebral amyloid angiopathy (CAA) is a common cause of lobar intracerebral hemorrhage (ICH) and cognitive impairment for which diagnostic criteria have been recently revised. A subset of CAA cases have superimposed inflammation in the form ...
Case Reports
Neurology. 2025 Jul 22;105(2):e213849. DOI:10.1212/WNL.0000000000213849 2025
Sudden Prehospital Deaths From Brain Arteriovenous Malformations: A Population-Based Study [0.03%]
基于人群的脑动静脉畸形院前突发死亡研究
Anni Pohjola,Aleksanteri Asikainen,Jaakko Kaprio et al.
Anni Pohjola et al.
Background and objectives: The number of unexpected prehospital deaths from brain arteriovenous malformations (AVMs) is unknown because existing mortality data are derived from hospital-based cohorts. In this study, we ai...