Incidence, Associations, and Mechanisms of Unexplained Early Neurologic Deterioration After Thrombectomy in Stroke Patients [0.03%]
血管内治疗后不明原因早期神经功能恶化的发生率、相关因素及可能机制
Umberto Pensato,Shelagh B Coutts,Brian van Adel et al.
Umberto Pensato et al.
Jeremy C S Johnson,Jessica Jiang,Mai-Carmen Requena-Komuro et al.
Jeremy C S Johnson et al.
Background and objectives: Hearing impairment is a major clinical issue in dementia. Acoustically altered speech (AAS) is a typical real-world listening challenge, but markers of AAS perception, especially in frontotempor...
Ischemic Lesion Net Water Uptake for the Prediction of Very Poor Functional Outcomes at 90 Days [0.03%]
缺血性病变净水分吸收量预测90天功能不良预后价值研究
Tobias Djamsched Faizy,Nils Werring,Christian Paul Stracke et al.
Tobias Djamsched Faizy et al.
Background and objectives: Recent trials have shown the efficacy of endovascular thrombectomy (EVT) in patients with acute ischemic stroke due to large vessel occlusion (AIS-LVO) and large infarcts on admission. However, ...
Child Neurology: Clinical and Imaging Findings in a Child With DHX37 Gene Variant: A Ribosomopathy Masquerading as Cerebral Palsy [0.03%]
DHX37基因突变患儿的临床及影像学特点报道——以疑似脑瘫为表现的核糖体病
Anika Menetrey,Mark Tarnopolsky,Sangeetha Yoganathan et al.
Anika Menetrey et al.
DEAH-Box helicase 37 (DHX37) gene, encoding an RNA-helicase, is essential for ribosome biogenesis. Pathogenic variants in the DHX37 gene result in a spectrum of ribosomopathies ranging from neurodevelopmental disorders with possible brain, ...
Can You Hear Me Now? Exploring Central Auditory Processing Deficits in Frontotemporal Dementia Syndromes [0.03%]
您现在能听见我说话吗？探讨额颞叶痴呆综合征中的中枢听觉处理缺陷
Tanav A Popli
Tanav A Popli
Child Neurology: Ataxia Telangiectasia Presenting With Isolated Chorea and Cutaneous Lesions [0.03%]
儿童神经病学：以孤立性皮质下 chorea 和皮肤病变起病的 telangiectasia毛细管扩张症患者一例
Maria Novelli,Vincenzo Leuzzi,Juan Deliz Gonzalez et al.
Maria Novelli et al.
CSF Aβ, Tau, Axonal, Synaptic, Glial, Neural, and Inflammatory Biomarkers in Patients With Sporadic Amyotrophic Lateral Sclerosis [0.03%]
散发性肌萎缩侧索硬化症患者脑脊液中的Aβ、Tau、轴突、突触、胶质和神经炎症生物标志物
Yujing Chen,Sujuan Sun,Zetai Bai et al.
Yujing Chen et al.
Background and objectives: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder with multifactorial pathophysiologic mechanisms, yet reliable CSF biomarkers for the diagnosis of ALS are lacking....
Associations of Chronic Insomnia, Longitudinal Cognitive Outcomes, Amyloid-PET, and White Matter Changes in Cognitively Normal Older Adults [0.03%]
慢性失眠与认知正常的老年人纵向认知结局、淀粉样PET和白质变化的关系
Diego Z Carvalho,Bhanu Prakash Kolla,Stuart J McCarter et al.
Diego Z Carvalho et al.
Background and objectives: The relationship between insomnia and cognitive decline is poorly understood. We investigated associations between chronic insomnia, longitudinal cognitive outcomes, and brain health in older ad...
Long-Term Open-Label Study Evaluating Oral Miglustat Treatment in Patients With Neuronal Ceroid Lipofuscinosis Type 3 [0.03%]
克拉屈滨治疗神经元 ceroid 淀粉样变病III型患者的长期开放标签研究
Nicola Pietrafusa,Marina Trivisano,Costanza Calabrese et al.
Nicola Pietrafusa et al.
Objectives: Neuronal ceroid lipofuscinosis type 3 (CLN3) is a rare lysosomal storage disorder characterized by progressive neurodegeneration. No disease-modifying treatments are currently available. Miglustat, a substrate...
Clinical Trial
Neurology. 2025 Oct 7;105(7):e214110. DOI:10.1212/WNL.0000000000214110 2025
Jonathan W Mink,Jennifer Vermilion
Jonathan W Mink