Association of Changes in Intrinsic Capacity With Cognitive Decline and Dementia: A Prospective Cohort Study [0.03%]
固有活动能力变化与认知功能下降和痴呆症关联的前瞻性队列研究
Qing-Mei Huang,Yun Li,Pei-Dong Zhang et al.
Qing-Mei Huang et al.
Background and objectives: Previous studies found that intrinsic capacity (IC) was an important risk factor for dementia. However, these studies focused on baseline IC, without considering the dynamic changes in IC. The s...
Role of the Upper Motor Neuron in the Generation of Fasciculations in Early Disease Stages of Amyotrophic Lateral Sclerosis [0.03%]
上运动神经元在肌萎缩侧索硬化早期阶段纤颤发生中的作用
Miguel Oliveira Santos,José Castro,Isabel Castro et al.
Miguel Oliveira Santos et al.
Background and objectives: The origin of fasciculation potentials (FPs) in the early stages of amyotrophic lateral sclerosis (ALS) remains a subject of debate. We investigated the role of the motor cortex in FP generation...
Factors Associated With Disability Improvement and Worsening Independent of Attacks in Patients With AQP4-IgG+ NMOSD and MOGAD: A Multicenter Cohort Study [0.03%]
AQP4-IgG阳性NMOSD和MOGAD患者的非发作性残疾改善与恶化相关因素：一项多中心队列研究
Daniel Engels,Patrick Schindler,Joachim Havla et al.
Daniel Engels et al.
Background and objectives: Disability trajectories in aquaporin-4 immunoglobulin G-seropositive neuromyelitis optica spectrum disorder (AQP4-IgG+ NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease ...
Multicenter Study
Neurology. 2026 Jul 28;107(2):e218199. DOI:10.1212/WNL.0000000000218199 2026
Cost-Effectiveness of Intracranial Aneurysm Screening: A Systematic Review [0.03%]
颅内动脉瘤筛查的成本效益：系统性综述
Andrei Schildt,Ilari Rautalin,Ville Vasankari et al.
Andrei Schildt et al.
Background and objectives: Subarachnoid hemorrhage (SAH) is associated with high mortality and long-term morbidity, as well as a considerable economic burden. Screening for unruptured intracranial aneurysms (UIAs) has the...
Rare Eating Epilepsy: Co-Occurrence of Focal Cortical Dysplasia and Gray Matter Heterotopia [0.03%]
罕见的饮食癫痫：局灶性皮质发育不良和灰质异位并存病例报告
Mengting Shi,Zhihui Yu,Yuan Xu et al.
Mengting Shi et al.
Spatiotemporal Associations Between Cortical Microinfarcts and Cortical Superficial Siderosis in Cerebral Amyloid Angiopathy [0.03%]
脑淀粉样血管病中皮质微梗死和皮质浅表铁沉积的时空关联性研究
Mattia Losa,Maria Clara Zanon Zotin,Thijs W van Harten et al.
Mattia Losa et al.
Background and objectives: Cerebral amyloid angiopathy (CAA) is a small vessel disease characterized by hemorrhagic and nonhemorrhagic brain injuries. While cortical cerebral microinfarcts (CMI) have been associated with ...
Blood-Brain Barrier Disruption Before Interhospital Transfer for Thrombectomy and Clinical Outcome [0.03%]
术前院际转诊对血脑屏障的影响及机械取栓的临床预后
Nefeli Eirini Valyraki,Richard Leigh,Adrien Ter Schiphorst et al.
Nefeli Eirini Valyraki et al.
Background and objectives: In acute ischemic stroke with large vessel occlusion (AIS-LVO), interhospital transfer for endovascular therapy (EVT) provides an ideal therapeutic window during which neuroprotective strategies...
Multicenter Study
Neurology. 2026 Jul 28;107(2):e218271. DOI:10.1212/WNL.0000000000218271 2026
At Death's Door: Cytosolic Dopamine in Patients With Parkinson Disease [0.03%]
帕金森病患者的细胞内多巴胺水平与死亡率的关系
Mark S LeDoux
Mark S LeDoux
Cerebral Artery Pulsatility, Premorbid Blood Pressure, and Small Vessel Disease on Brain Imaging: A Population-Based Study [0.03%]
基于人群的脑动脉脉动、病前血压与脑影像小血管疾病的关联研究
Linxin Li,Sara Mazzucco,Gary Kui Kai Lau et al.
Linxin Li et al.
Background and objectives: Increased pulsatility of cerebral blood flow is proposed as a potential cause of cerebral small vessel disease (SVD), but the apparent association could be confounded by shared vascular risk fac...
Genetic Risk for Alzheimer Disease, Midlife Hypertension, and Dementia: The ARIC Neurocognitive Study [0.03%]
阿尔茨海默病遗传风险、中年高血压与痴呆症——ARIC神经认知研究结果
Valerie N Morrill,James Russell Pike,Jiaqi Hu et al.
Valerie N Morrill et al.
Background and objectives: Genetics represent a nonmodifiable risk factor for Alzheimer disease (AD), with 60%-80% heritability. Midlife hypertension is a modifiable risk factor for both dementia and death. Our primary ob...