Armaan K Malhotra,Avery B Nathens,Husain Shakil et al.
Armaan K Malhotra et al.
Background and objectives: Days alive and at home (DAH) is a validated outcome measure that captures health care transitions between time spent at home vs various nonhome care settings, offering a more nuanced patient-cen...
Multicenter Study
Neurology. 2026 Feb 24;106(4):e214571. DOI:10.1212/WNL.0000000000214571 2026
α-Synuclein Seed Amplification Assays: High Promise, Real-World Variability, and an Urgent Need for Standardization [0.03%]
α-突触核蛋白种子增殖实验：广阔前景、现实世界的差异性以及亟待解决的标准化问题
Giovanni Bellomo,Federico Paolini Paoletti
Giovanni Bellomo
Jeffrey T Howard,Ian J Stewart
Jeffrey T Howard
Association Between Longitudinal Rate of Change in CSF Biomarkers and Subsequent Tau PET Burden in Early Braak Stages [0.03%]
纵向脑脊液生物标志物变化率与早期Braak期tau-PET沉积负荷之间的关系
Nisha Rani,Abhay Moghekar,Daniel D Callow et al.
Nisha Rani et al.
Background and objectives: Changes in CSF and tau PET biomarkers of Alzheimer disease (AD) emerge years before clinical symptoms are observed. However, few studies have examined the temporal relationship between these mea...
Impact of Antidepressant Use and Serotonergic Profile on Short-Term Outcome of Traumatic Brain Injury: Retrospective Nationwide Cohort Study [0.03%]
抗抑郁药使用及五羟色胺能特征对创伤性脑损伤短期预后影响的回顾性全国队列研究
Jussi P Posti,Aleksi Tornio,Jori O Ruuskanen et al.
Jussi P Posti et al.
Background and objectives: Concerns have been raised that the use of serotonergic antidepressants may increase the risk of intracranial hemorrhage and worsen outcomes following traumatic brain injury (TBI). However, large...
Diagnostic Performance of the α-Synuclein Seed Amplification Assay for Dementia With Lewy Bodies: A Comparison Across 4 Laboratories [0.03%]
α-突触核蛋白种子增殖试验在多巴胺能病理诊断中的表现：四项实验室间的比较研究
Rakesh Kumar,Stephanie Gravett,Vesna Jelic et al.
Rakesh Kumar et al.
Background and objectives: The α-synuclein (α-syn) seed amplification assay (SAA) has shown promising results for diagnosing dementia with Lewy bodies (DLB) using CSF samples. A barrier to implementing α-syn SAA clinic...
Comparative Study
Neurology. 2026 Feb 24;106(4):e214614. DOI:10.1212/WNL.0000000000214614 2026
Progressive Changes in Brain Morphology in People With Idiopathic Generalized Epilepsy [0.03%]
原发性全面性癫痫患者脑形态的进展性改变
Fenglai Xiao,Yingying Zhang,Britta Wandschneider et al.
Fenglai Xiao et al.
Background and objectives: Idiopathic generalized epilepsy (IGE) is typically responsive to treatment, yet some people remain poorly controlled despite multiple antiseizure medication trials. Whether this subgroup shows p...
Long-Term Effectiveness and Persistence Factors of Anti-CGRP Monoclonal Antibodies in Migraine: 2-Year Results From the EUREkA Cohort [0.03%]
抗CGRP单克隆抗体治疗偏头痛的长期疗效及影响因素：EUREKＡ队列研究两年期结果分析
Edoardo Caronna,Rut Mas-de-Les-Valls,Gabriella Egeo et al.
Edoardo Caronna et al.
Objectives: The aim of this study was to describe the long-term effectiveness and treatment persistence of anti-calcitonin gene-related peptide (CGRP) monoclonal antibodies (MAbs) in migraine and to identify baseline fact...
Observational Study
Neurology. 2026 Feb 24;106(4):e214659. DOI:10.1212/WNL.0000000000214659 2026
Author Response: Seizures and Epilepsy in Association With Neurocysticercosis: A Nosologic Proposal [0.03%]
与神经囊尾蚴病相关的癫痫和癲痫发作：一个分类学建议
Josemir W Sander,Gagandeep Singh,Hector H Garcia et al.
Josemir W Sander et al.
Editors' Note: Seizures and Epilepsy in Association With Neurocysticercosis: A Nosologic Proposal [0.03%]
编者按：与囊尾蚴病相关的癫痫发作和癫痫：一项分类学建议
James Ernest Siegler,Steven L Galetta
James Ernest Siegler