Safety and extrapulmonary effects of elexacaftor-tezacaftor-ivacaftor in people with cystic fibrosis following lung transplantation: A systematic review and meta-analysis [0.03%]
艾瑞昔替尼--tezacaftor-_ivacaftor对肺移植后囊性纤维化患者的安全性和肺外影响：系统评价和.meta.分析
Laura Venditto,Amber Neece,Federico Forgione et al.
Laura Venditto et al.
Background & aims: Elexacaftor-tezacaftor-ivacaftor is a cystic fibrosis transmembrane conductance regulator modulator used in people with cystic fibrosis. Currently, the paucity of efficacy data for extrapulmonary manife...
CFTR modulators: eligibility, pseudomonas burden and justifying life-long therapy [0.03%]
囊性纤维化跨膜传导调节物：使用指征、铜绿假单胞菌感染以及长期治疗的合理性
Dominic A Fitzgerald
Dominic A Fitzgerald
Recent advances in pediatric pulmonology and allergy: Articles of interest to fellows. Subclinical small airway dysfunction, anti-inflammatory reliever therapy, and biologic treatment in pediatric asthma [0.03%]
儿科肺病和过敏领域的最新进展：住院医感兴趣的论文。儿童哮喘的亚临床小气道功能障碍、抗炎缓解治疗以及生物制剂治疗
Irlanda Alvarado-Amador,Seda Tunca,Chiara Astori
Irlanda Alvarado-Amador
Recent advances in pediatric asthma continue to refine the understanding of disease mechanisms and to reshape therapeutic strategies. In this brief review, we discuss three recent articles of particular interest to fellows and early-career ...
Beyond the score: advancing quantitative lung ultrasound in the early postnatal period [0.03%]
评分之外：新生儿早期肺部超声定量分析的进展
Frédérique N Donnelly,Victoria Leith,Arun Sett
Frédérique N Donnelly
Oral health status in adult and paediatric patients with cystic fibrosis (CF): A systematic review and meta-analysis [0.03%]
囊性纤维化患者的口腔健康状况：系统回顾和荟萃分析
Alessandro Cuozzo,Leopoldo Mauriello,Vitolante Pezzella et al.
Alessandro Cuozzo et al.
The aim of this study was to evaluate oral health in paediatric and adult patients affected by cystic fibrosis (CF). A systematic review was conducted following PRISMA guidelines. Electronic search was performed on scientific databases to i...
Rebecca Jackson,Siân Bentley,Jane C Davies et al.
Rebecca Jackson et al.
The availability of highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators has transformed outcomes for people with cystic fibrosis (pwCF). Eligibility, conferred initially by clinical trial data, has evolved...
Targeting neutrophil-driven inflammation in bronchopulmonary dysplasia: From pathogenesis to therapeutic perspectives [0.03%]
中性粒细胞驱动的支气管肺发育不良炎症靶向治疗：从发病机制到治疗前景
Maria Giulia Conti,Rebecca Morelli,Elvira Mazzuca et al.
Maria Giulia Conti et al.
Neutrophil-driven inflammation plays a key role in the initiation and progression of the chronic lung disease of preterm infants, also known as bronchopulmonary dysplasia (BPD). Their modulation represents a promising avenue for early risk ...
Immunomodulation in paediatric inflammatory interstitial lung diseases: towards mechanism-based targeted therapies, a focus on the anti-cytokines [0.03%]
儿科炎症间质性肺疾病的免疫调节：基于机制的靶向治疗研究，重点介绍抗细胞因子疗法
Apolline Gonsard,Marie-Louise Fremond,Alice Hadchouel
Apolline Gonsard
Childhood interstitial lung diseases (chILDs) associated with inflammatory diseases represent a heterogeneous group of rare conditions. To date, therapeutic approaches predominantly rely on broad-spectrum immunosuppressive agents, often ind...
Introduction of a video-based heterogeneity index for quantitative lung ultrasound assessment in neonates with respiratory distress - a proof-of-concept study [0.03%]
基于视频的异质性指数在呼吸窘迫新生儿肺部超声评估中的介绍——一项概念验证研究
Melina Winkler,Thomas Suppan,Alana Seigner et al.
Melina Winkler et al.
Background: Lung ultrasound (LUS) is an established bedside tool for assessing neonatal respiratory distress. However, conventional semi-quantitative LUS scoring relies on subjective interpretation and may miss subtle but...
Year in review: "Best" papers in pediatric pulmonary and sleep medicine in 2025 [0.03%]
2025年儿科学研究回顾：“最佳”儿科肺部和睡眠医学论文
M E Soto-Martinez,B K Rubin
M E Soto-Martinez
With an ever increasing number of excellent publications in the field of pediatic pulmonary and sleep medicine each year, it is a challenge to identify those with the greatest impact and interest for readers of this journal. The challenge w...