Smart inhalers in paediatric asthma: bridging the gap between innovation and clinical practice [0.03%]
智能吸入器在儿童哮喘中的应用：弥合创新与临床实践之间的差距
David Drummond,Job F M van Boven,Boudewijn J H Dierick et al.
David Drummond et al.
Smart inhaler systems represent a major opportunity to transform paediatric asthma care by potentially addressing three fundamental problems affecting paediatric asthma outcomes: medication adherence, inhalation technique and reliever overu...
Precision medicine to diagnose asthma in preschool children: comparison of clinical scores, lung function, biomarkers, and genetic tests [0.03%]
精准医学在学龄前儿童哮喘诊断中的应用：临床评分、肺功能、生物标志物和基因检测的比较
Jose A Castro-Rodriguez,Gustavo Nino,Asher Tal et al.
Jose A Castro-Rodriguez et al.
Asthma is an umbrella term for several phenotypes and endotypes. It most frequently begins before the age of 6, with significant morbidity and decline in lung function occurring among all pediatric age groups. A delay in the diagnosis of as...
Kasama Manothummetha,Matthew Wyke,Gary Kleiner et al.
Kasama Manothummetha et al.
Respiratory symptoms are among the most common presentations of inborn errors of immunity (IEI) and acquired immunodeficiencies in children. Pediatric pulmonologists are often the first to evaluate these patients, yet immunologic evaluation...
Editorial: Overlooked and underdone: Treatment of ear and nasal problems in children [0.03%]
编者按：被忽视且治疗不足的儿童耳鼻问题
Dominic A Fitzgerald,Hannah North
Dominic A Fitzgerald
Could Glucagon-Like Peptide-1 (GLP-1) receptor antagonists be used to treat obstructive sleep apnoea in children and adolescents with obesity? [0.03%]
GLP-1受体拮抗剂可否用于治疗肥胖儿童和青少年的阻塞性睡眠呼吸暂停？
Dilan Silva,Louise Baur,Dominic A Fitzgerald
Dilan Silva
Obstructive sleep apnoea (OSA) and obesity may co-exist in children and adolescents. Childhood obesity tends to persist into adulthood. Sustained weight loss is recommended for obesity and OSA but may be very difficult to achieve and mainta...
Jose A Castro-Rodriguez,Manuel E Soto-Martínez,Carlos E Rodriguez-Martinez et al.
Jose A Castro-Rodriguez et al.
Although severe asthma in low- and middle-income countries (LMICs) is relatively uncommon in children and adolescents (2.1 % and 4.3 %, respectively), it results in significant morbidity, occasional fatality, and great challenges of managem...
Editorial: Exercise empowering children socially and physically from vulnerable ex preemies to elite athletes and all of those in between [0.03%]
社论：从弱势早产儿到精英运动员——赋能儿童社交和身体锻炼至关重要
Larry C Lands,Dominic A Fitzgerald
Larry C Lands
Oscar Camilo Pantoja-Gomez,Juanita Agudelo-Agudelo,Elida Duenas-Meza et al.
Oscar Camilo Pantoja-Gomez et al.
As survival rates for premature infants improve, understanding the link between prematurity and obstructive sleep apnea (OSA) has become critical for enhancing outcomes in this high-risk population. Children born severely prematurely face a...
Latika Gupta,Michele Arigliani,James Cook et al.
Latika Gupta et al.
Omalizumab, a monoclonal antibody targeting IgE, was the first biologic therapy approved in 2003 for treating severe, allergen-driven, therapy-resistant asthma. Since then, many new biologics have been approved for use in children, targetin...
Mimi Lu,Dominic A Fitzgerald
Mimi Lu
Parents commonly report in sleep questionnaires and in person to clinicians that their child is restless in sleep. There is little agreement on what constitutes restless sleep and so the significance of this observation is uncertain and its...