Zhenwu decoction ameliorates adriamycin-induced nephrotic syndrome in rats via dual modulation of AVP-V2R-AQP2 and RAAS-MR-AQP3 pathways [0.03%]
真武汤通过调节AVP-V2R-AQP2和RAAS-MR-AQP3两条通路改善腺苷诱导的肾病综合征研究
Mengmeng Xu,Min Du,Wanying Qu et al.
Mengmeng Xu et al.
The core bioactive components of Zhenwu Decoction (ZWD)-utilized for managing kidney diseases-and the associated anti-nephrotic syndrome (NS) edema mechanism remain incompletely characterized. We assessed the potential mechanism of ZWD agai...
Platelet-to-high-density lipoprotein cholesterol ratio as a potential mediator in the obesity-chronic kidney disease association among hypertensive patients [0.03%]
高血压患者中血小板高密度脂蛋白胆固醇比值在肥胖与慢性肾脏病关联中的介导作用研究
Xun Huang,Weihua Liu,Qinghua Liu et al.
Xun Huang et al.
This study investigated the relationship between the platelet-to-high-density lipoprotein cholesterol ratio (PHR) and chronic kidney disease (CKD) in a hypertensive population, exploring its mediating role in the obesity-CKD association. Us...
Hemoglobin variability predicts mortality in acute kidney injury patients undergoing continuous renal replacement therapy: a multi-database cohort study [0.03%]
急性肾损伤患者连续肾脏替代治疗时血红蛋白波动预测死亡率：多数据库队列研究
Yumin Huang,Ran Jiang,Kang Liu et al.
Yumin Huang et al.
Background: Short-term hemoglobin variability (Hb-ARV) during continuous renal replacement therapy (CRRT) may reflect blood volume instability in acute kidney injury (AKI), yet its mortality implications remain unclear. ...
Multicenter Study
Renal failure. 2025 Dec;47(1):2598121. DOI:10.1080/0886022X.2025.2598121 2025
Phenotypic and genotypic analysis of pediatric nephronophthisis patients with different levels of proteinuria [0.03%]
不同蛋白尿水平儿童肾纤症患者的表型及基因型分析
Qiuxia Chen,Jing Ouyang,Fei Zhao et al.
Qiuxia Chen et al.
While nephronophthisis (NPHP) classically manifests as mild tubular proteinuria, emerging evidence reports nephrotic-range proteinuria with edema. This study aims to explore the phenotypes and genotypes of pediatric NPHP patients with diffe...
Hemoadsorption therapy in severe rhabdomyolysis: a report from the international, prospective COSMOS (CytOSorb® TreatMent of Critically ill PatientS) registry [0.03%]
国际前瞻性COSMOS（CytOSorb®治疗重症患者）登记处肌溶解症血液吸附疗法的报告
Ricard Ferrer,Bartosz Tyczynski,Julian Kreutz et al.
Ricard Ferrer et al.
Severe rhabdomyolysis is associated with an increased risk of acute kidney injury (AKI) and mortality. Hemoadsorption may reduce myoglobin levels and mitigate AKI. The COSMOS registry is a prospective, multicenter, observational study evalu...
Observational Study
Renal failure. 2025 Dec;47(1):2600720. DOI:10.1080/0886022X.2025.2600720 2025
Blood pressure variability and cerebrovascular risk in maintenance hemodialysis versus peritoneal dialysis: a comparative study [0.03%]
维持性血液透析与腹膜透析患者的血压变异性和脑血管风险：一项对比研究
Ting Hu,Ting Yu,Xiao Xu et al.
Ting Hu et al.
This study aimed to compare blood pressure variability (BPV) between maintenance hemodialysis (HD) and peritoneal dialysis (PD) patients and evaluate its association with cerebrovascular event risk. A prospective cohort of 374 end-stage ren...
Comparative Study
Renal failure. 2025 Dec;47(1):2590798. DOI:10.1080/0886022X.2025.2590798 2025
Immune mechanisms and immunomodulatory therapies in steroid-resistant nephrotic syndrome [0.03%]
糖皮质激素抵抗性肾病综合征的免疫机制和免疫调节疗法
Junchao Deng,Lizhen Zhu,Xiaoshi Zhu
Junchao Deng
Steroid-resistant nephrotic syndrome (SRNS) is a complex and refractory kidney disease generally causing chronic kidney dysfunction, characterized by persistent proteinuria despite prolonged corticosteroid therapy. This review comprehensive...
Impact of diabetes on survival and clinical outcomes in elderly patients receiving peritoneal dialysis [0.03%]
糖尿病对接受腹膜透析患者的生存率及临床结果的影响分析
Luyao Xu,Yue Qian,Qianhui Song et al.
Luyao Xu et al.
This study investigated the clinical outcomes and mortality risks in elderly peritoneal dialysis (PD) patients with diabetes mellitus (DM). A total of 210 incident PD patients aged 70 years or older (mean age 80.7 ± 5.0 years; 60.5% men) w...
Donor kidney pathology combined with clinical parameters helps expand the kidney donor pool: a large-scale retrospective cohort study [0.03%]
供者肾脏病理结合临床参数有助于扩大肾脏捐献池子：一项大规模回顾性队列研究
Meifang Wang,Sulin Luo,Xinyi Gao et al.
Meifang Wang et al.
Objectives: The disparity between kidney demand and supply necessitates the expansion of the donor pool. This study evaluates the long-term outcomes of single kidney transplantation guided by histological and clinical par...
From glycemic variability to digital signal biomarker: a prognostic and precision medicine framework for sepsis-associated acute kidney injury [0.03%]
从血糖波动到数字信号生物标志物：用于脓毒症相关急性肾损伤的预后和精准医学框架
Xia Ma,Shiping Zhu,Chuanchuan Sun et al.
Xia Ma et al.
Sepsis, a condition with substantial global morbidity and mortality, frequently leads to sepsis-associated acute kidney injury (SA-AKI). While glycemic variability (GV) correlates with adverse outcomes in critically ill populations, its pro...