Calciphylaxis in chronic kidney disease: a systematic review of pathomechanisms and risk factors for calcific uremic arteriolopathy [0.03%]
慢性肾脏病钙化性血管炎的系统评价：发病机制和钙化性尿毒症小动脉病变的风险因素
Cecilie Søndergaard,Subagini Nagarajah,Jianlin Shen et al.
Cecilie Søndergaard et al.
Calcific uremic arteriolopathy (CUA) is a rare, severe condition affecting patients with chronic kidney disease (CKD). The etiology of CUA is unclear. Here, we aimed to identify factors associated with its development. We reviewed the exist...
An epidemiological assessment of hemodialysis, continuous kidney replacement therapy, and peritoneal dialysis in pediatric acute kidney injury patients [0.03%]
儿科急性肾损伤患者血液透析、持续肾脏替代治疗和腹膜透析的流行病学评估
Sanat Subhash,Ethan Kalina,Jacob Almeda et al.
Sanat Subhash et al.
Introduction: Hemodialysis (HD), peritoneal dialysis (PD), and continuous kidney replacement therapy (CKRT) are major modalities of kidney replacement therapy (KRT) in pediatric acute kidney injury (AKI). This study uses ...
Pill burden and health-related quality of life across dialysis modalities: a multimodal assessment using KDQOL-36 and eQ-5D-5L [0.03%]
不同透析模式下的服药负担和健康相关生活质量的多模式评估（采用KDQOL-36和eQ-5D-5L）
Suthiya Anumas,Tassamon Jankaew,Montira Khienlikit et al.
Suthiya Anumas et al.
Background and hypothesis: Patients receiving maintenance dialysis experience substantial pill burden from complex comorbidities and intensive treatment regimens. Although higher pill burden is linked to treatment burden ...
Integrative multi-omics analysis identifies VCAN and ESM1 as candidate cell-type-associated biomarkers of NET-related glomerular injury in diabetic kidney disease [0.03%]
整合多组学分析识别出VCAN和ESM1作为候选细胞类型相关生物标志物，用于糖尿病肾病中神经内分泌细胞相关的肾小球损伤
Yufeng Liang,Chenlun Li,Binsan Huang et al.
Yufeng Liang et al.
Diabetic kidney disease (DKD) involves complex inflammatory and microvascular injury, but cell-specific molecular signatures linked to neutrophil extracellular traps (NETs) remain unclear. We aimed to identify NET-associated biomarkers of g...
Anti-nephrin autoantibodies in post-transplant recurrence of focal segmental glomerulosclerosis: a review [0.03%]
抗系膜抗体与局灶节段性肾小球硬化症移植复发：综述
Yuhong Ye,Fei Liu
Yuhong Ye
Emerging studies have identified autoantibodies targeting the podocyte protein nephrin in patients with post-transplant recurrent focal segmental glomerulosclerosis (FSGS). These antibodies bind nephrin, directly disrupting its downstream s...
An explainable machine learning model for predicting in-hospital infection in patients with systemic lupus erythematosus [0.03%]
一种用于预测系统性红斑狼疮患者住院期间感染的可解释机器学习模型
Jiabao Liu,Yong Wang,Zheyi Dong et al.
Jiabao Liu et al.
Infection is a leading cause of mortality in patients with systemic lupus erythematosus (SLE), yet effective tools for early identification of high-risk patients are lacking. This study aimed to develop an explainable machine learning (ML) ...
A study on risk factors for the progression from T2DM to end-stage renal disease based on Mendelian randomization and logistic regression analysis [0.03%]
基于孟德尔随机化和逻辑回归分析的2型糖尿病发展至终末期肾病风险因素研究
Yakun Wang,Xinjia Guo,Yanhong Li et al.
Yakun Wang et al.
Using two-sample Mendelian randomization (MR) based on GWAS data from the IEU OpenGWAS project and a retrospective clinical cohort, this study investigated risk factors for progression from type 2 diabetes mellitus (T2DM) to end-stage renal...
Kidney failure risk equation and early renal risk in adults with sickle cell disease: comparison with KDIGO classification using measured GFR [0.03%]
基于测量的GFR与KDIGO分类比较下的成人镰状细胞病患者的肾衰风险方程和早期肾风险
Yannick Mompango Engole,Jean-Robert Rissassy Makulo,Yannick Mayamba Nlandu et al.
Yannick Mompango Engole et al.
Chronic kidney disease is a major complication of sickle cell disease (SCD), but early kidney injury frequently occurs despite preserved or increased glomerular filtration rate (GFR), potentially limiting the usefulness of conventional kidn...
Comparative Study
Renal failure. 2026 Dec;48(1):2699576. DOI:10.1080/0886022X.2026.2699576 2026
Indoxyl sulfate exacerbates chronic inflammation and susceptibility to severe infection via modulating T-cell CD73/adenosine signaling in chronic kidney disease [0.03%]
吲哚硫酸盐通过调节慢性肾脏病中T细胞CD73/腺苷信号通路加剧慢性炎症和严重感染的易感性
JiLai Cao,Yuxin Nie,Xuesen Cao et al.
JiLai Cao et al.
Background: Chronic kidney disease (CKD) is a major global health issue. Cardiovascular events and infections drive mortality in end-stage renal disease via immune dysregulation. The role of T-cell purinergic signaling an...
Proactive iron supplementation alone in patients on chronic hemodialysis is not sufficient [0.03%]
慢性血透患者的补铁干预单用口服补铁不足取
Panna Pribelszki,Máté Szász,Mihály Tapolyai
Panna Pribelszki
Dialysis patients often become iron-deficient because of many factors, including poor iron absorption from the gut, blood loss during dialysis, frequent blood draws, phosphate binders, and the use of erythropoietin. Oral supplementation is ...