A prospective, randomized, double-blind, placebo-controlled, multicenter study of thiamin plus folic acid in the treatment of cognitive impairment in patients undergoing maintenance hemodialysis [0.03%]
Kewei Xie,Yan Jiang,Tingfang Chen et al.
Kewei Xie et al.
This prospective, randomized, double-blind, placebo-controlled trial investigated the efficacy and safety of thiamin and folic acid for cognitive impairment in maintenance hemodialysis (MHD) patients. A total of 215 MHD patients aged 18-75 ...
Randomized Controlled Trial
Renal failure. 2026 Dec;48(1):2658981. DOI:10.1080/0886022X.2026.2658981 2026
Fengning Yang,Kewu Wang,Jiayi Chu et al.
Fengning Yang et al.
Diabetic kidney disease (DKD) is a major complication of diabetes mellitus. Iron metabolism is implicated in the pathogenesis of DKD; however, its mechanistic basis and therapeutic implications remain incompletely explored. Here, we employe...
Mineralocorticoid receptor antagonists in dialysis patients after ACHIEVE and ALCHEMIST: updated systematic review and meta-analysis of 14 randomized trials [0.03%]
Yifan Zhu,Juan Li,Zhongping Huang et al.
Yifan Zhu et al.
End-stage kidney disease (ESKD) patients receiving dialysis bear a heavy burden of cardiovascular disease (CVD), the leading cause of mortality. Mineralocorticoid receptor antagonists (MRAs) have cardiovascular protective effects in non-dia...
Jian Han,Lanxin Ma,Heng Luo
Jian Han
Gitelman syndrome (GS) is a rare hereditary kidney disorder characterized by electrolyte abnormalities. However, its systemic manifestations, such as growth retardation, suggest broader metabolic disturbances. To investigate this issue, we ...
Adverse pregnancy outcomes, longitudinal change in eGFR, and incident hypertension in women: a population-based cohort study [0.03%]
Marzieh Saei Ghare Naz,Maryam Mousavi,Maryam Farahmand et al.
Marzieh Saei Ghare Naz et al.
Background: As the traditional risk factors cannot account for all hypertension (HTN) incidents, it is of great importance to determine other risk factors. This study aimed to identify long-term HTN risk associated with a...
In-hospital electronic monitoring system approaches to epidemiologic investigation and predictive modeling of contrast-induced acute kidney injury [0.03%]
Xingyue Zheng,Youjun Xu,Shuaibo Wang et al.
Xingyue Zheng et al.
Contrast-induced acute kidney injury (CI-AKI), the third most common cause of hospital-acquired kidney injury, is associated with poor clinical outcomes, highlighting the need for accurate prediction. In this study, we used an electronic ho...
Functional urine production and glomerular maturation from embryonic metanephros transplanted at the renal hilum in rats [0.03%]
Kailin Li,Chao Sun,Xianzhen Yang et al.
Kailin Li et al.
End-stage renal disease remains a major global health burden, and novel regenerative strategies are urgently needed. Embryonic metanephros transplantation has emerged as a promising approach, but the optimal site for engraftment and functio...
Long-term outcomes of interventional therapy for transplant renal artery stenosis: a 5-year follow-up study [0.03%]
Xueyu Li,Xiangyong Tian,Xin Jiang et al.
Xueyu Li et al.
This study evaluated the long-term outcomes of interventional therapy for transplant renal artery stenosis (TRAS). A total of 30 TRAS patients who underwent interventional treatment between February 2017 and September 2020 were included. Gr...
Impact of combined ECMO - CRRT support on patient outcomes and risk factors: a multicenter retrospective study [0.03%]
Xin Wang,Yueguo Wang,Pengfei Ren et al.
Xin Wang et al.
Objective: This study aimed to investigate the association of continuous renal replacement therapy (CRRT) use with the prognosis of patients undergoing extracorporeal membrane oxygenation (ECMO) and to explore its relatio...
Multicenter Study
Renal failure. 2026 Dec;48(1):2640290. DOI:10.1080/0886022X.2026.2640290 2026
Necroptosis and the RIPK1-RIPK3-MLKL pathway in chronic kidney disease: mechanisms, crosstalk, and therapeutic opportunities [0.03%]
Jiawei Lu,Ying Wang,Yalin Cheng et al.
Jiawei Lu et al.
Chronic kidney disease (CKD) is a prevalent global health concern with a high worldwide prevalence rate. It is defined by a steady deterioration in renal function, which causes toxins and metabolic waste to build up and cause systemic probl...