Explainable machine learning framework using visceral adiposity index to predict cardiorenal syndrome: a survey-weighted NHANES study with SHAP interpretation [0.03%]
使用内脏脂肪指数预测心肾综合征的可解释机器学习框架：具有SHAP解释的NHANES调查加权研究
Sikai Xu,Xiaoyun Sun,Zhiyi Ouyang et al.
Sikai Xu et al.
Cardiorenal syndrome (CRS) involves bidirectional pathophysiology between cardiovascular and renal dysfunction. The visceral adiposity index (VAI), a sex-specific composite metric, serves as an indicator of visceral adipose accumulation and...
Preoperative serum Raman spectroscopy and machine learning for predicting postoperative acute kidney injury after acute type A aortic dissection [0.03%]
急性A型主动脉夹层术前血清拉曼光谱和机器学习预测术后急性肾损伤
Xiaopeng Mei,Shuman Ji,Yongpo Jiang et al.
Xiaopeng Mei et al.
Acute type A aortic dissection (ATAAD) represents an aggressive cardiovascular condition with substantial morbidity and mortality rates. Postoperative acute kidney injury (AKI) is a complication that contributes significantly to worse progn...
Irisin targets the HK1-glycolysis-NLRP3 pyroptosis axis to prevent chronic kidney disease-associated vascular calcification [0.03%]
irisin靶向HK1-糖酵解-NLRP3炎性小体轴预防慢性肾脏病相关血管钙化
Weijia Xu,Peiwen Wang,Xiaowen Zhu et al.
Weijia Xu et al.
Vascular calcification (VC) in chronic kidney disease (CKD) remains a critical clinical challenge with limited therapeutic options. This study investigates the regulatory role of HK1-mediated glycolysis in NLRP3 inflammasome-driven pyroptos...
Novel obesity biomarkers as mortality predictors in individuals with CKD: a comparative analysis with traditional anthropometric measures [0.03%]
新型肥胖生物标志物在CKD患者中的死亡预测价值及其与传统体质测量指标的比较分析
Shigao Xu,Tieshi Liu
Shigao Xu
The a body shape index (ABSI) and body roundness index (BRI) represent novel obesity biomarkers. This study aimed to determine their predictive capabilities for mortality risk in individuals with chronic kidney disease (CKD) and to compare ...
Comparative Study
Renal failure. 2025 Dec;47(1):2610908. DOI:10.1080/0886022X.2025.2610908 2025
Monika Gooz
Monika Gooz
Psychosocial pathways linking family support to sleep disorders in maintenance hemodialysis: the chain mediating role of depression and fatigue [0.03%]
家庭支持通过心理社会途径与维持性血液透析患者睡眠障碍的关系：抑郁和疲劳的连锁中介作用
Hong Tan,Li Li,Yipei Zhang et al.
Hong Tan et al.
Sleep disorders are prevalent in maintenance hemodialysis (MHD) patients and contribute to reduced quality of life, cardiovascular risk, and mortality. While psychosocial factors influence sleep quality, the pathways linking family support ...
Serum steroid metabolome pattern is associated with the response to prednisolone therapy of male patients with IgA nephropathy [0.03%]
男性IgA肾病患者接受(pred)治疗的反应与血清类固醇代谢模式相关
Petr Kosztyu,Martin Hill,Marta Velikova et al.
Petr Kosztyu et al.
IgA nephropathy (IgAN) is characterized by the deposition of galactose-deficient IgA1 (Gd-IgA1)-containing immune complexes into kidney mesangium leading to glomerular inflammation and injury. In patients with active IgAN non-responding to ...
Soluble guanylate cyclase modulators-a novel therapeutic approach for diabetic kidney disease [0.03%]
可溶性鸟苷酸环化酶激动剂-糖尿病肾脏病的新型治疗方法
Yuqing Xu,Xuan Wu,Mingpai Ge et al.
Yuqing Xu et al.
Diabetic kidney disease (DKD) is a common complication, affecting approximately 40% of patients with diabetes and imposing substantial health and economic burdens worldwide. As DKD prevalence rises, existing treatments remain limited in eff...
Effects of rhEPO-Fc on chronic renal anemia in Chinese patients undergoing maintenance hemodialysis: a multicenter, randomized, open-label, and phase 3 study [0.03%]
一项评价重组人促红细胞生成素-融合蛋白治疗维持性血液透析中国慢性肾病贫血患者疗效和安全性的多中心、随机、开放、 III期临床试验
Liangying Gan,Xinlu Gao,Jingchun Yao et al.
Liangying Gan et al.
Recombinant human erythropoietin (rhEPO) fused with human immunoglobulin G (IgG) Fc fragment (rhEPO-Fc) is a novel erythropoiesis-stimulating agent designed to extend plasma half-life and enhance biological activity. However, data on the ef...
Clinical Trial
Renal failure. 2025 Dec;47(1):2597648. DOI:10.1080/0886022X.2025.2597648 2025
PCSK9 inhibitors: a promising lipid-lowering strategy for kidney transplant recipients [0.03%]
PCSK9抑制剂在肾移植受者中降脂治疗的前景
Bohan Luo,Ling Guo,Wenjia Di
Bohan Luo
Recent advancements in transplant techniques and immunosuppressive drugs have improved long-term survival rates and increased the age of transplant recipients. Dyslipidemia has become a major complication, leading to atherosclerotic cardiov...