Association of the dietary inflammation index DII with the prevalence of chronic kidney disease in patients with hypertension [0.03%]
饮食炎症指数与高血压患者慢性肾脏病患病率的关系分析
Xin Lu,Shuang Zhou,Shujun Liu et al.
Xin Lu et al.
Background and objective: Chronic kidney disease (CKD) is a global health concern that is frequently associated with hypertension. Inflammation is an important factor in the development of both illnesses. The Dietary Infl...
Screening of active components in Astragalus mongholicus Bunge and Panax notoginseng formula for anti-fibrosis in CKD: nobiletin inhibits Lgals1/PI3K/AKT signaling to improve renal fibrosis [0.03%]
防己黄芪汤与田七粉方中抗肾纤维化有效成分筛选：柚皮素通过抑制Lgals1/PI3K/AKT信号改善肾纤维化
Fang Yang,Tong Li,Xiao-Qian Zhang et al.
Fang Yang et al.
The Astragalus mongholicus Bunge and Panax notoginseng formula (A&P) has been clinically shown to effectively slow down the progression of chronic kidney disease (CKD) and has demonstrated significant anti-fibrosis effects in experimental C...
Luyan Bian,Yuchao Niu,Weijie Yuan et al.
Luyan Bian et al.
Background: Podocytes, as intrinsic renal cells, can also express MHC-II and costimulatory molecules under inflammatory conditions, suggesting that they may act as antigen-presenting cells (APCs) to activate immune cell r...
SGLT2 inhibitor dapagliflozin reduces proximal tubular cell damage biomarkers in patients with acute heart failure [0.03%]
达格列净减少急性心力衰竭患者近端小管细胞损伤标志物
Pongsathorn Gojaseni,Jananya Wattanakul,Anan Chuasuwan et al.
Pongsathorn Gojaseni et al.
Development and validation of a nomogram for predicting refractory peritoneal dialysis related peritonitis [0.03%]
预测顽固性腹膜透析相关性腹膜炎列线图的建立和验证
Qiqi Yan,Guiling Liu,Ruifeng Wang et al.
Qiqi Yan et al.
Objective: To identify the risk factors of refractory peritoneal dialysis related peritonitis (PDRP) and construct a nomogram to predict the occurrence of refractory PDRP. ...
Chlorogenic acid alleviates renal fibrosis by reducing lipid accumulation in diabetic kidney disease through suppressing the Notch1 and Stat3 signaling pathway [0.03%]
氯ogenic酸通过抑制Notch1和Stat3信号通路减少糖尿病肾脏疾病中脂质积累从而缓解肾纤维化
Xiao-Ying Yang,Die Jiang,Yuan-Zhu Wang et al.
Xiao-Ying Yang et al.
Aims: Abnormal renal lipid metabolism causes renal lipid deposition, which leads to the development of renal fibrosis in diabetic kidney disease (DKD). The aim of this study was to investigate the effect and mechanism of ...
Estimated small dense low-density lipoprotein-cholesterol and the risk of kidney and cardiovascular outcomes in diabetic kidney disease [0.03%]
糖尿病肾病患者的估计小而密低密度脂蛋白胆固醇与肾脏和心血管结局风险的关系
Qing Yang,Yutong Zou,Yanlin Lang et al.
Qing Yang et al.
Aims: This study aimed to investigate the correlations between estimated small dense low-density lipoprotein-cholesterol (esd-LDL-c) and the development of end-stage kidney disease (ESKD), cardiovascular mortality, and al...
Mesangial cell-derived CircRNAs in chronic glomerulonephritis: RNA sequencing and bioinformatics analysis [0.03%]
慢性肾小球肾炎中系膜细胞源circRNA的研究：RNA测序及生物信息学分析
Ji Hui Fan,Xiao Min Li
Ji Hui Fan
Background: Circular RNAs (circRNAs) have been shown to play critical roles in the initiation and progression of chronic glomerulonephritis (CGN), while their role from mesangial cells in contributing to the pathogenesis ...
Causal relationship between Helicobacter pylori infection and IgA nephropathy: a bidirectional two-sample mendelian randomization study [0.03%]
基于孟德尔随机化方法研究幽门螺旋杆菌感染与IgA肾病的因果关系：双向两样本MR研究
Shuhui Jing,Ling Lin,Jiaxing Li et al.
Shuhui Jing et al.
IgA nephropathy (IgAN) is one of the most common primary glomerulonephritis, and serum Helicobacter pylori (H. pylori) antibody levels are increased in patients with IgA N, but the role of H. pylori infection in the pathogenesis of IgAN is ...
Role of the gut microbiota in cefoperazone/sulbactam-induced epilepsy in mice with chronic renal failure [0.03%]
肠道菌群在cefoperazone/sulbactam致慢性肾衰小鼠癫痫发作中的作用
Yulu Wu,Donghua Gu,Jie Li et al.
Yulu Wu et al.
Objectives: The mechanism of cefoperazone/sulbactam-induced epilepsy in chronic kidney disease (CKD) patients is not yet clear. We hypothesized that cefoperazone/sulbactam-induced epilepsy could be based on two main facto...