Exploring the association between volatile organic compound exposure and chronic kidney disease: evidence from explainable machine learning methods [0.03%]
基于可解释机器学习方法探讨挥发性有机化合物暴露与慢性肾脏疾病关联性研究
Liyan Jiang,Hongling Wang,Yang Xiao et al.
Liyan Jiang et al.
Background: Chronic Kidney Disease (CKD) affects approximately 697.5 million people worldwide. Volatile organic compounds (VOCs) are emerging as potential risk factors, but their complex relationships with CKD may be unde...
Development and validation of a nomogram combining cytokines with traditional clinical parameters in predicting the risk of postoperative sepsis after ureteroscopic lithotripsy [0.03%]
结合细胞因子和传统临床参数预测输尿管镜碎石术后脓毒症风险的列线图模型的构建及验证
Shuai Liu,Hongmin Zhou,Zeyu Chen et al.
Shuai Liu et al.
Background: Sepsis is one of the most severe complications of ureteroscopic lithotripsy (URSL) surgery and is the main cause of death in hospitalized patients. Traditional preoperative patient management and risk assessme...
C-reactive protein-to-prealbumin ratio as prognostic marker in hemodialysis patients with Omicron infection [0.03%]
C-反应蛋白与前白蛋白比值在新冠病毒奥密克戎感染维持性血液透析患者中的预后价值研究
Quanchao Zhang,Caibao Lu,Zhifen Wu et al.
Quanchao Zhang et al.
Background: Hemodialysis patients frequently experience chronic inflammation and malnutrition, while C-reactive protein to prealbumin ratio (CP ratio) is a comprehensive assessment approach of inflammatory and nutritional...
Multicenter Study
Renal failure. 2025 Dec;47(1):2512404. DOI:10.1080/0886022X.2025.2512404 2025
Paraspinous muscle sarcopenic indices for predicting mortality in patients undergoing hemodialysis [0.03%]
腰背肌萎缩参数预测血液透析患者的死亡风险
Takahiro Yajima,Kumiko Yajima
Takahiro Yajima
Background: We examined the association between computed tomography (CT)-derived paraspinous muscle density (PSMD) and index (PSMI) and all-cause mortality in patients undergoing hemodialysis. ...
Reduced glutathione ameliorates sepsis-induced acute kidney injury in mouse model: involvement of cuproptosis [0.03%]
还原型谷胱甘肽通过抑制铜依赖性细胞死亡改善脓毒症诱导的急性肾损伤：小鼠模型中的机制研究
Lu Wang,Long Jiang,Jingjing Wang et al.
Lu Wang et al.
Background: Cuproptosis, a copper-induced form of programmed cell death, has been implicated in the pathogenesis of acute kidney injury (AKI) and sepsis. Reduced glutathione (GSH), a potent antioxidant, exhibits both anti...
Kidney diseases and single-cell sequencing research: a bibliometric analysis from 2015 to 2024 [0.03%]
肾脏疾病与单细胞测序研究：2015-2024年文献计量分析
Yaotan Li,Jinyi Hou,Xinghua Zhang et al.
Yaotan Li et al.
Background: Single-cell RNA sequencing (scRNA-seq) has revolutionized kidney disease research by enabling high-resolution transcriptomic analysis at the cellular level. This technology can overcome the limitations of trad...
Brennan Winkler,Kasey Lerner,Joshua H Lipschutz
Brennan Winkler
The primary cilium is an organelle found on different cell types in many organs, and is important for human health including the kidney. Diseases due to abnormal or absent cilia are termed ciliopathies and ADPKD is one of the most common ci...
Low sirtuin-1 levels are linked to erythropoietin resistance in hemodialysis patients [0.03%]
低寿蛋白-1水平与血液透析患者促红细胞生成素抵抗有关
Ebru Hekimgil,Cuma Bulent Gul
Ebru Hekimgil
Introduction: Erythropoiesis-stimulating agents (ESAs) are widely used to manage anemia in chronic hemodialysis patients. However, some individuals exhibit ESA resistance, and its underlying mechanisms remain unclear. Sir...
Multi-target regulation of cellular senescence by traditional Chinese medicine: a novel strategy to preventing diabetic kidney disease [0.03%]
中药多靶点调控细胞衰老：防治糖尿病肾病的新策略
Chen Wang,Dongfeng Chen,Yonghui Yin et al.
Chen Wang et al.
Diabetic kidney disease (DKD) is a common chronic microvascular complication of diabetes and the leading cause of end-stage renal disease. Its pathogenesis is closely linked to cellular senescence. Studies have shown that cellular senescenc...
Panaxatriol saponins exert anti-renal fibrosis by suppressing TNF-α mediated inflammation and TGF-β1/Smad3 signaling pathway [0.03%]
人参三醇型皂苷通过抑制TNF-α介导的炎症和TGF-β1/Smad3信号通路发挥抗肾纤维化作用
Si Yi,Feiyan Li,Xin Ma et al.
Si Yi et al.
Renal fibrosis is a key pathological process in the progression of chronic kidney disease (CKD). Panaxatriol saponins (PTS), the main bioactive compounds extracted from Panax notoginseng (Burk.) F.H. Chen, have demonstrated antioxidative an...