Bone marrow-derived mesenchymal stem cells reduce CCl4-induced kidney injury and fibrosis in male Wistar rats [0.03%]
骨髓间充质干细胞减少CCl4致雄性Wistar大鼠肾脏损伤及纤维化
Asmaa Adel,Manal Abdul-Hamid,Samraa H Abdel-Kawi et al.
Asmaa Adel et al.
Aim: This study explores the possible therapeutic role of rats and mice bone marrow-derived mesenchymal stem cells (BM-MSCs) on renal damage and toxicity brought on by carbon tetrachloride (CCl4) in Wistar rats. ...
Association of plasma microRNA-16-5p and abdominal aortic calcification in maintenance hemodialysis patients [0.03%]
血浆微小核糖核酸-16-5p与维持性血液透析患者腹主动脉钙化的关系
Qiaojing Liang,Chen Fu,Yingjie Liu et al.
Qiaojing Liang et al.
Recent studies have shown that microRNA-16-5p (miR-16-5p) plays a crucial role in the pathological mechanism of vascular calcification. Nevertheless, the expression profile of miR-16-5p in maintenance hemodialysis (MHD) patients who are pre...
The prognostic value of the systemic immune inflammation index in patients with IgA nephropathy [0.03%]
系统免疫炎症指数对IgA肾病患者预后的价值分析
Yaling Zhai,Shuaigang Sun,Wenhui Zhang et al.
Yaling Zhai et al.
Background: Immune and inflammatory factors are considered the basic underlying mechanisms of IgA nephropathy (IgAN). The systemic immune inflammation index (SII) is a new inflammatory biomarker and has been identified as...
Mesenchymal stem cell-derived exosomes ameliorate diabetic kidney disease through NOD2 signaling pathway [0.03%]
间充质干细胞衍生的外泌体通过NOD2信号途径改善糖尿病肾病
Yinghui Wang,Donglin Lu,Shasha Lv et al.
Yinghui Wang et al.
Background and aims: Diabetic kidney disease (DKD) is one of the most common complications of diabetes. It is reported that mesenchymal stem cells (MSCs) derived exosomes (MSCs-Exo) may have great clinical application pot...
Causal role of immune cells in IgA nephropathy: a mendelian randomization study [0.03%]
IgA肾病中免疫细胞的致病作用:一项孟德尔随机化研究
Jinlian Shu,Yating Ge,Yonggui Wu
Jinlian Shu
Background: Previous observational studies have shown that immune cells play an important role in IgA nephropathy. However, the specific causal relationship between the two is inconsistent. ...
Changes in the spectrum of biopsy-proven renal diseases over 11 years: a single-center study in China [0.03%]
中国单中心11年肾活检证实的肾脏病谱变迁研究
Yujia Wang,Liyin Zhang,Li Yuan et al.
Yujia Wang et al.
Background: There have been some shifts in the frequency and distribution of biopsy-proven renal diseases in China over recent years. The aim of the study was to investigate the changing spectrum of renal diseases from th...
Establishing a differential diagnosis model between primary membranous nephropathy and non-primary membranous nephropathy by machine learning algorithms [0.03%]
基于机器学习算法建立原发性膜性肾病与继发性膜性肾病的鉴别诊断模型
Shangmei Cao,Shaozhe Yang,Bolin Chen et al.
Shangmei Cao et al.
Context: Four algorithms with relatively balanced complexity and accuracy in deep learning classification algorithm were selected for differential diagnosis of primary membranous nephropathy (PMN). ...
Continuous aspirin treatment improves cardiovascular events and all-cause mortality in hemodialysis patients with peripheral artery disease [0.03%]
持续服用阿司匹林可改善外周动脉疾病血液透析患者的心血管事件和全因死亡率
Chung-Kuan Wu,Noi Yar,Yun-Yi Chen
Chung-Kuan Wu
Background: Hemodialysis (HD) patients with peripheral arterial disease (PAD) are at heightened risk of adverse vascular events, and aspirin positively affects those outcomes. We aimed to investigate the association betwe...
A meta-analysis and review on the effectiveness and safety of renal denervation in managing heart failure with reduced ejection fraction [0.03%]
射频消融肾动脉交感神经术对射血分数降低的心力衰竭疗效和安全性的meta分析及综述
Quanbin Su,Jiaxin Li,Futian Shi et al.
Quanbin Su et al.
Objective: This study aimed to systematically evaluate the effectiveness and safety of renal denervation (RDN) in managing heart failure with reduced ejection fraction (HFrEF). ...
Medicinal evaluation and molecular docking study of osajin as an anti-inflammatory, antioxidant, and antiapoptotic agent against sepsis-associated acute kidney injury in rats [0.03%]
奥斯荆对大鼠脓毒症急性肾损伤的药效学评价及分子对接研究
Mohammad Alhilal,Huseyin Serkan Erol,Serkan Yildirim et al.
Mohammad Alhilal et al.
Despite efforts to find effective drugs for sepsis-associated acute kidney injury (SA-AKI), mortality rates in patients with SA-AKI have not decreased. Our study evaluated the protective effects of isoflavone osajin (OSJ) on SA-AKI in rats ...