Causal relationships between gut microbiota and IgA nephropathy: evidence from Mendelian randomization and microbiome validation [0.03%]
基于孟德尔随机化和微生物组验证的肠道菌群与IgA肾病间的因果关系证据
Xin Wang,Jiong Liu,Wuda Huoshen et al.
Xin Wang et al.
Background: Emerging evidence links gut microbiota strongly with IgA Nephropathy (IgAN). However, the causal role of specific gut microbiota in IgAN remains unclear. This study used a two-sample Mendelian randomization (M...
Identification of core noncoding RNA-associated competing endogenous RNA networks in renal fibrosis via whole-transcriptome sequencing [0.03%]
通过全转录组测序鉴定肾脏纤维化中核心非编码RNA相关竞争性内源RNA网络
Yizhen Chen,Meng Cheng,Rong Dai et al.
Yizhen Chen et al.
Objective: This study aimed to investigate noncoding RNA (ncRNA) expression changes in renal fibrosis (RF) models induced by three distinct etiologies using whole-transcriptome RNA sequencing, identify overlapping differe...
Intraoperative 20% albumin infusion and acute kidney injury in on-pump cardiac surgery: a focus on preoperative albumin levels [0.03%]
术中输注20%白蛋白与体外循环心脏手术中的急性肾损伤：重点探讨术前白蛋白水平的影响
Han Zhang,Shujie Yan,Luyu Bian et al.
Han Zhang et al.
Background: Albumin is widely used for volume replacement therapy during cardiopulmonary bypass (CPB) including priming fluid, despite significant controversy over its benefits. This study aimed to examine how 20% exogeno...
Exploring the link between A Body Shape Index and abdominal aortic calcification in chronic kidney disease: a cross-sectional analysis from 2013-2014 National Health and Nutrition Examination Survey [0.03%]
基于2013-2014年美国国家健康和营养调查的横断面研究：探索慢性肾脏病患者身体形态指数与腹主动脉钙化的关联性分析
Yang Li,Kun Zou,Yixuan Wang et al.
Yang Li et al.
Background: Abdominal aortic calcification (AAC) is prevalent in chronic kidney disease (CKD) patients and linked to elevated cardiovascular disease (CVD) risk. Obesity, linked to both CKD and CVD, can be better assessed ...
Exploring the relationship between graft dysfunction with serum metabolites and inflammatory proteins: integrating Mendelian randomization, single-cell analysis, machine learning, and SHAP methods for comprehensive analysis [0.03%]
基于孟德尔随机化、单细胞分析、机器学习和SHAP方法综合分析移植物功能障碍与血清代谢物和炎症蛋白关系研究
Jiyuan Li,Kankan Shui,Longkai Peng et al.
Jiyuan Li et al.
Background: The exact mechanism of graft dysfunction has not been fully clarified. We aimed to explore the causal effects of serum metabolites on graft dysfunction and the mediating role of inflammatory proteins. ...
Characteristics of adult membranous nephropathy patients with capillary co-deposition of IgG and IgA [0.03%]
成人膜性肾病患者IgG和IgA共沉积的临床特征分析
Yi Guan,Aiping Liu,Qionghong Xie et al.
Yi Guan et al.
Background: Membranous nephropathy (MN) is characterized by subepithelial immune complex deposits of IgG, particularly anti-Phospholipase A2 Receptor (anti-Pla2r). However, presence of IgA co-deposition along subepithelia...
Smurf2 knockdown attenuates the progression of diabetic nephropathy by inhibiting mesangial cell proliferation and fibrosis through suppressing EYA2 ubiquitination [0.03%]
SMURF2敲低通过抑制EYA2泛素化减轻糖尿病肾病中系膜细胞增殖和纤维化
Lizhen Chen,Yuqing Chen,Fei Liu et al.
Lizhen Chen et al.
Diabetic nephropathy (DN) is a serious microvascular complication of diabetes and the main cause of end-stage renal disease. Smurf2 is a member of ubiquitin ligases. In this study, we aimed to investigate the mechanism by which Smurf2 media...
The influencing factors of phosphate control behavior among patients undergoing hemodialysis: based on the health belief model [0.03%]
血液透析患者磷管理行为的影响因素——基于健康信念模型的分析
Manman Gao,Jinrong Zhu,Weiwei Zhao et al.
Manman Gao et al.
Purpose: Improving the adherence to phosphate management is crucial for reducing the incidence of mortality and complications and improving quality of life for patients undergoing hemodialysis. This study aimed to investi...
Multicenter Study
Renal failure. 2025 Dec;47(1):2522969. DOI:10.1080/0886022X.2025.2522969 2025
Application of serum STIM1, AOPPS, and urinary NGAL, AGT in the diagnosis of hypertensive nephropathy [0.03%]
血清STIM1、AOPPs和尿液NGAL、AGT在高血压肾病诊断中的应用研究
Baohua Li,Chunsheng Wang,Deng Ouyang et al.
Baohua Li et al.
Objective: We aim to explore the diagnostic value of early detection of serum stromal interaction molecule 1 (STIM1), advanced oxidation protein products (AOPPs), urinary neutrophil gelatinase-associated lipocalin (NGAL),...
Different patterns of brain iron deposition exist in peritoneal dialysis and hemodialysis patients with cognitive impairment [0.03%]
不同模式的脑铁沉积存在于认知障碍腹膜透析和血液透析患者中
Jiamin Liu,Wenbo Yang,Lijun Song et al.
Jiamin Liu et al.
Background: The incidence of cognitive impairment in patients with peritoneal dialysis (PD) and hemodialysis (HD) has been increased, but the specific mechanism is not clear. Disruption of iron homeostasis is associated w...