Identification of hub fatty acid metabolism-related genes and immune infiltration in IgA nephropathy [0.03%]
IgA肾病中脂肪酸代谢相关关键基因及免疫浸润识别
Xiaoqian Qian,Shuyang Bian,Qin Guo et al.
Xiaoqian Qian et al.
Aims: To investigate the potential mechanisms of fatty acid metabolism (FAM)-related genes in IgA nephropathy (IgAN) and to explore its immune cell infiltration characteristic. ...
Noninvasive genetic testing for type IV collagen nephropathy using oral mucosa DNA sampling in children with haematuria [0.03%]
应用口腔黏膜DNA样本进行儿童血尿患者Ⅳ型胶原肾病的无创基因检测研究
Jiaojiao Liu,Dayin Zhou,Xiaowen Wang et al.
Jiaojiao Liu et al.
Objective: Hematuria is one of the most common conditions in children, and increase the risk of chronic kidney disease. Persistent hematuria may be the earliest manifestation of type IV collagen-related nephropathy. Early...
Lycopene alleviates 5-fluorouracil-induced nephrotoxicity by modulating PPAR-γ, Nrf2/HO-1, and NF-κB/TNF-α/IL-6 signals [0.03%]
番茄红素通过调节PPAR-γ、Nrf2/HO-1和NF-κB/TNF-α/IL-6信号缓解5-氟尿嘧啶诱导的肾毒性
Ghadeer M Albadrani,Ahmed E Altyar,Osama A Kensara et al.
Ghadeer M Albadrani et al.
5-Fluorouracil (5-FU) is one of the most used anticancer drugs. However, its nephrotoxicity-associated drawback is of clinical concern. Lycopene (LYC) is a red carotenoid with remarkable anti-inflammatory and anti-oxidative properties. In t...
Prediction of dialysis adequacy using data-driven machine learning algorithms [0.03%]
基于数据驱动的机器学习算法预测透析充分性
Yi-Chen Liu,Ji-Ping Qing,Rong Li et al.
Yi-Chen Liu et al.
Background: Adequate delivery of hemodialysis (HD), measured by the spKt/V derived from urea reduction, is an important determinant of clinical outcomes in chronic hemodialysis patients. However, the need for pre- and pos...
Risk factors, management and outcomes for peritoneal dialysis access damage [0.03%]
腹膜透析通路受损的风险因素、处理及转归
Ruoxi Liao,Xueli Zhou,Xia Liu et al.
Ruoxi Liao et al.
Objectives: Peritoneal dialysis (PD) access damage is an uncommon complication of PD. This study aimed to describe the characteristics, management and outcomes of PD access damage. ...
Glymphatic system dysfunction in nondialysis-dependent ESRD patients with diabetic kidney disease: associations with clinical characteristics and cognitive function [0.03%]
糖尿病肾病非透析依赖性ESRD患者中胶淋巴系统功能障碍及其与临床特点和认知功能的关系
Bingxin Yu,Wenbo Yang,Lijun Song et al.
Bingxin Yu et al.
Objectives: To investigate glymphatic function in nondialysis-dependent ESRD (ND-ESRD) patients with diabetic kidney disease (DKD) or non-DKD using the diffusion tensor image analysis along the perivascular space (DTI-ALP...
A nomogram to predict the risk of relapse in patients with minimal change disease: a retrospective cohort study [0.03%]
一项预测微小病变型肾病患者复发风险的预后图表：回顾性队列研究
Lefeng Wang,Qinfan Yao,Ying Zhang et al.
Lefeng Wang et al.
Background: Minimal change disease (MCD) is a common pathological type of nephrotic syndrome. Relapses of MCD present a significant challenge for patients. This study aims to develop a predictive model for evaluating the ...
Histone deacetylase 9 promotes osteogenic trans-differentiation of vascular smooth muscle cells via ferroptosis in chronic kidney disease vascular calcification [0.03%]
组蛋白脱乙酰酶9通过促进慢性肾脏病血管钙化中血管平滑肌细胞的成骨转分化来调节铁死亡
Lin Xiong,Qiong Xiao,Rong Chen et al.
Lin Xiong et al.
Vascular calcification, a common complication of chronic kidney disease (CKD), remains an unmet therapeutic challenge. The trans-differentiation of vascular smooth muscle cells (VSMCs) into osteoblast-like cells is crucial in the pathogenes...
Piezo1 facilitates the initiation and progression of renal fibrosis by mediating cell apoptosis and mitochondrial dysfunction [0.03%]
Piezo1通过介导细胞凋亡和线粒体功能障碍促进肾纤维化的启动和进展
Yanping Zhang,Lei Lv,Zhaokai Zhou et al.
Yanping Zhang et al.
Renal fibrosis is the major pathological changes of Chronic kidney disease (CKD). Piezo1, a mechanical sensitive ion channel, is implicated in organ fibrosis. However, the precise role of Piezo1 in CKD fibrosis is unknown. The aims of this ...
A predictive model based on serum bicarbonate for cardiovascular events after initiation of peritoneal dialysis [0.03%]
基于血清碳酸氢根预测腹膜透析后心血管事件的模型
Dashan Li,Rongxue Liu,Xiangming Qi et al.
Dashan Li et al.
Background: The risk of cardiovascular events (CVEs) in peritoneal dialysis (PD) patients is high, but varies widely among individuals. Metabolic acidosis is prevalent in PD patients and may be involved in the development...
Observational Study
Renal failure. 2024 Dec;46(2):2422428. DOI:10.1080/0886022X.2024.2422428 2024