Hesperetin attenuates ischemia/reperfusion-induced acute kidney injury by regulating ferroptosis in mice [0.03%]
芸香素通过调节铁死亡抑制小鼠缺血再灌注急性肾损伤
Xiaoyu Xie,Chen Guan,Ningxin Zhang et al.
Xiaoyu Xie et al.
Background: Acute kidney injury (AKI) is a complex syndrome often resulting from ischemia/reperfusion (I/R) injury (IRI). Due to the significant role of ferroptosis in AKI pathogenesis, therapeutic strategies targeting fe...
Glomerular mesangial derived extracellular vesicles deteriorate diabetic kidney disease via miR-3147/PRKAR2B axis [0.03%]
系膜来源的细胞外囊泡通过miR-3147/PRKAR2B轴恶化糖尿病肾脏疾病
Jiayan Zhang,Fan Zhao,Yiying Tao et al.
Jiayan Zhang et al.
To investigate the clinical significance and role of miRNAs with shared patterns in both peripheral blood and kidney tissue-derived extracellular vesicles (EVs) in diabetic kidney disease (DKD). miRNA-Seq was performed on plasma EV samples ...
Suicide risk in patients undergoing hemodialysis: a systematic review and meta-analysis of prevalence [0.03%]
血液透析患者的自杀风险：患病率的系统评价和荟萃分析
Luigi Zerbinati,Federica Caccia,Federica Baciga et al.
Luigi Zerbinati et al.
Background: Kidney failure is strongly associated with psychological disorders, including anxiety, depression, and suicidal ideation. However, the prevalence of suicide risk in patients undergoing dialysis has not been fu...
Meta-Analysis
Renal failure. 2025 Dec;47(1):2521453. DOI:10.1080/0886022X.2025.2521453 2025
Mediation effects of age, intramuscular adipose tissue index and serum albumin on survival status in initial dialysis patients [0.03%]
年龄、肌内脂肪组织指数及血清白蛋白对初透析患者生存状态的中介效应研究
Meng-Huan Wu,Yu-Ting Gao,Yu-Xin Ren et al.
Meng-Huan Wu et al.
Background: To explore the associations of age, intramuscular adipose tissue index (IATI), and serum albumin with survival status in initial dialysis patients and the mediating effects. ...
Optimizing preparation of renal biopsy specimens for TEM: a time-efficient approach to rapid diagnosis of kidney diseases [0.03%]
优化肾活检标本的透射电子显微镜检查准备：快速诊断肾脏疾病的有效方法
Gen Wang,Xiaodong Zhu,Shaoshan Liang et al.
Gen Wang et al.
Electron microscopic examination of renal biopsies is crucial for the diagnosis of kidney disease. In this study, we present an optimized protocol that significantly reduces processing time to 19.5 h, compared to 120 h with conventional met...
ALKBH5 induces macrophage activation to promote renal fibrosis via Retnla [0.03%]
ALKBH5通过Retnla诱导巨噬细胞活化促进肾纤维化
Long Zheng,Wenjun Gao,Zhenan Zhang et al.
Long Zheng et al.
Renal fibrosis is a common pathological endpoint of various chronic kidney diseases. Macrophages play an important role in the pathophysiological process of renal fibrosis. However, the exact function and molecular mechanism of macrophages ...
Gut microbiota implication in diabetic kidney disease: mechanisms and novel therapeutic strategies [0.03%]
糖尿病肾病的肠道菌群机制及新的治疗策略
Yujie Zhang,Jianbo Qing,Yasin Abdi Saed et al.
Yujie Zhang et al.
Diabetic kidney disease (DKD) is one of the leading causes of chronic kidney disease and end-stage renal disease worldwide, predominantly driven by the rise in type 2 diabetes mellitus. Recent evidence highlights the crucial role of gut mic...
Urinary and plasma donor-derived cell-free DNA for noninvasive monitoring of BK polyomavirus-associated nephropathy in kidney transplant recipients: a prospective cohort study [0.03%]
尿源性和血浆来源的游离DNA用于非侵入性监测肾移植受者的BK多瘤病毒相关性肾病：一项前瞻性队列研究
Luying Guo,Sulin Luo,Rongfang Shen et al.
Luying Guo et al.
Background: BK polyomavirus-associated nephropathy (BKPyVAN) is a major cause of allograft injury and dysfunction in kidney transplant recipients. Current monitoring tools, including viremia and biopsy, have limitations i...
Seasonal variations in acute kidney injury incidence and outcomes: a multicenter prospective observational study highlighting socioeconomic disparities [0.03%]
急性肾损伤的季节性变化及结局：一项多中心前瞻性观察研究，揭示了社会经济差异问题
Ali AlSahow,Omar Alkandari,Naser AlSabti et al.
Ali AlSahow et al.
Background: Kuwait experiences cool winters and hot summers. We evaluated the impact of ambient temperature in these two seasons on acute kidney injury (AKI) incidence and outcomes, and assessed difference between Kuwaiti...
Observational Study
Renal failure. 2025 Dec;47(1):2520421. DOI:10.1080/0886022X.2025.2520421 2025
Associations between per- and polyfluoroalkyl substances exposure and renal function as well as poor prognosis in chronic kidney disease patients [0.03%]
全氟和多氟烷基物质暴露与慢性肾脏病患者肾功能及预后之间的关联研究
Jiayin Wang,Tianyun Gao,Xiaohua Li et al.
Jiayin Wang et al.
Objectives: The objectives of this study were to investigate the associations of single and mixed exposure to the environmental pollutants per- and polyfluoroalkyl substances (PFAS) with renal function and mortality in no...