Screening potential diagnostic biomarkers for PLA2R‑associated idiopathic membranous nephropathy by WGCNA analysis and LASSO algorithm [0.03%]
WGCNA分析和LASSO算法筛选PLA2R相关特发性膜性肾病潜在诊断标志物
Jinxu Huang,Yaqing Huang,Xiaoling Zeng et al.
Jinxu Huang et al.
Adult nephrotic syndrome is primarily caused by membranous nephropathy (MN), with idiopathic membranous nephropathy (IMN) being a prominent subtype. The onset of phospholipase A2 receptor (PLA2R1)-associated IMN is critically linked to M-ty...
Monocyte to high-density lipoprotein cholesterol ratio as a marker of the presence and progression of diabetic kidney disease [0.03%]
单核细胞高密度脂蛋白胆固醇比率作为糖尿病肾脏疾病存在和进展的标志物
Wentao Yang,Yuanlong Zhong,Pengying Zhou et al.
Wentao Yang et al.
Background: Monocyte to high-density lipoprotein cholesterol ratio (MHR) is considered a novel marker of inflammation. However, whether MHR can predict the risk of diabetic kidney disease (DKD) remains uncertain. Our rese...
Association of geriatric nutritional risk index with renal prognosis and all-cause mortality among older patients with chronic kidney disease: a secondary analysis of CKD-ROUTE study [0.03%]
老年慢性肾脏病患者营养风险指数与肾脏预后和全因死亡率的关系:CKD-ROUTE研究的二次分析
Lei Chen,Mengyao Yan,Jie Li et al.
Lei Chen et al.
Objectives: The aim of the study was to assess the association between the geriatric nutritional risk index (GNRI) and incidence of CKD progression, all-cause mortality, and cardiovascular events in the elderly patients w...
IGFBP2 and IGFBP4 interact to activate complement pathway in diabetic kidney disease [0.03%]
胰岛素样生长因子结合蛋白2和4在糖尿病肾病中相互作用以激活补体途径
Jieling Liang,Yangxiao Huang,Daping Peng et al.
Jieling Liang et al.
Background: Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease globally. Recent research has identified insulin-like growth factor-binding proteins 2 (IGFBP2) and 4 (IGFBP4) as potential biomarke...
Association of tea consumption with all-cause/cardiovascular disease mortality in the chronic kidney disease population: an assessment of participation in the national cohort [0.03%]
茶消费与慢性肾脏病人群的全因/心血管疾病死亡率的关系:来自全国队列参与者的评估研究
Jin Li,Xing-Ling Chen,Xiao-Lu Ou-Yang et al.
Jin Li et al.
Background: While there are numerous benefits to tea consumption, its long-term impact on patients with chronic kidney disease (CKD) remains unclear. Meth...
Copper-instigated modulatory cell mortality mechanisms and progress in kidney diseases [0.03%]
铜诱发的调节细胞死亡机制及肾脏疾病进展
Xiya Ren,Limei Zhao,Yajie Hao et al.
Xiya Ren et al.
Copper is a vital cofactor in various enzymes, plays a pivotal role in maintaining cell homeostasis. When copper metabolism is disordered and mitochondrial dysfunction is impaired, programmed cell death such as apoptosis, paraptosis, pyropt...
Chronic kidney disease management in patients with a failing graft: a comparative study with incident non-transplant hemodialysis patients [0.03%]
肾移植失败患者的慢性肾脏病管理与初诊透析患者对比研究
Ana Rita Silva,Maria Guedes Marques,Luís Rodrigues et al.
Ana Rita Silva et al.
Moderate-severe aortic arch calcification and high serum alkaline phosphatase co-modify the risk of cardiovascular events and mortality among chronic hemodialysis patients [0.03%]
中重度主动脉弓钙化和高血清碱性磷酸酶共同修饰慢性血液透析患者的心血管事件和死亡风险
Cheng-Hao Chang,Hung-Hsiang Liou,Chung-Kuan Wu
Cheng-Hao Chang
Background: Patients with end-stage kidney disease undergoing chronic hemodialysis (HD) have an unparalleled risk of vascular calcification (VC) and high alkaline phosphatase (Alk-P) levels. However, whether VC contribute...
The natural immune molecules urinary Tamm-Horsfall protein and pentraxin 3 as predictors for recurrent urinary tract infection severity: a single-center self-control study [0.03%]
尿源性天然免疫分子THP和PTX3作为预测反复发作的尿路感染严重程度的标志物:一项单中心自身对照研究
Zongping Li,Yingru Xu,Qian Wang et al.
Zongping Li et al.
Objective: The innate immune defense plays a pivotal role in protecting the urinary tract from uropathogenic invasion and maintaining immune homeostasis. Dysregulation of the innate immune system can result in recurrent u...