Inflammatory markers mediate association of AIP with kidney failure risk: data from National Health and Nutrition Examination Survey (NHANES) 2005-2018 [0.03%]
炎症标志物介导AIP与肾功能衰竭风险之间的关联：来自2005-2018年全国健康和营养调查（NHANES）的数据
Chengjing Guan,Ruixue Chen,Yu Wang
Chengjing Guan
Dyslipidemia and inflammation often coexist in the progression of kidney failure, with the atherosclerosis index of plasma (AIP) serving as a valuable marker for monitoring dyslipidemia. This cross-sectional study analyzed data from the Nat...
Development and validation of multi-center serum creatinine-based models for noninvasive prediction of kidney fibrosis in chronic kidney disease [0.03%]
基于多中心血清肌酐的非侵入性预测慢性肾脏病患者肾纤维化的模型建立及验证
Le-Hao Wu,Dan Zhao,Jian-Ying Niu et al.
Le-Hao Wu et al.
Objective: Kidney fibrosis is a key pathological feature in the progression of chronic kidney disease (CKD), traditionally diagnosed through invasive kidney biopsy. This study aimed to develop and validate a noninvasive, ...
Multicenter Study
Renal failure. 2025 Dec;47(1):2489715. DOI:10.1080/0886022X.2025.2489715 2025
The impact of rising peripheral blood naïve CD8+ T cell levels on chronic kidney disease onset: a Mendelian randomization study [0.03%]
外周血 naive CD8+ T细胞水平升高对慢性肾脏病发病影响的孟德尔随机化研究
Jianbo Qing,Yiting Zhao,Junnan Wu
Jianbo Qing
Background: The global incidence of chronic kidney disease (CKD) is rising rapidly. Immune cells play a crucial role in the onset and progression of CKD, however, the causal relationships and underlying immunological mech...
Analysis of the trajectory of cognitive function changes and influencing factors in maintenance hemodialysis patients: a prospective longitudinal study [0.03%]
维持性血液透析患者认知功能变化轨迹及影响因素分析：一项前瞻性队列研究
Wenbin Xu,Xiaolian Long,Yuhe Xiang et al.
Wenbin Xu et al.
Objectives: To explore the trajectory of cognitive function changes and influencing factors in maintenance hemodialysis (MHD) patients. Methods: ...
The m6A reader YTHDF2 protects vascular smooth muscle cells against the osteogenic differentiation through targeting Runx2 [0.03%]
M6A“阅读蛋白”YTHDF2通过靶向Runx2保护血管平滑肌细胞免遭成骨分化损伤
Lanmei Li,Meijuan Cheng,Jingjing Jin et al.
Lanmei Li et al.
Vascular calcification (VC) is an important pathological development progress in chronic kidney disease (CKD) and may increase mortality but lacks effective treatments. N6-methyladenosine (m6A) has been verified to be the most prevalent int...
Dihydromyricetin protects against cisplatin-induced renal injury and mitochondria-mediated apoptosis via the EGFR/HSP27/STAT3 signaling pathway [0.03%]
二氢杨梅素通过EGFR/HSP27/STAT3信号途径保护顺铂引起的肾损伤和线粒体介导的细胞凋亡作用
Zheming Xu,Minjing Zhang,Xue Zhang et al.
Zheming Xu et al.
Background: Cisplatin (CP) has been used as an effective chemotherapy drug for different types of cancers. Despite its therapeutic benefits, the clinical utility of CP is often hindered by adverse effects, notably acute k...
miR-1225-3p regulates fibrosis in mesangial cells via SMURF2-mediated ubiquitination of ChREBP in diabetic kidney disease [0.03%]
MiR-1225-3p通过SMURF2介导的ChREBP泛素化调节糖尿病肾脏疾病中系膜细胞纤维化
Juntai Zhang,Yan Cai,Yan Qin et al.
Juntai Zhang et al.
Background: Diabetic kidney disease (DKD), characterized by mesangial fibrosis and renal dysfunction, is a major microvascular complication of diabetes. Studies have shown that miRNAs are closely related to the progressio...
Research trends and performance of endothelin A receptor antagonist in kidney care: a bibliometric analysis [0.03%]
内皮素A受体拮抗剂在肾脏病领域研究趋势及绩效的计量学分析
Wisit Cheungpasitporn,Pajaree Krisanapan,Supawadee Suppadungsuk et al.
Wisit Cheungpasitporn et al.
Background: Endothelin A receptor antagonists (ERAs) have emerged as pivotal therapeutic agents in managing pulmonary hypertension (PH) and various kidney disorders, including chronic kidney disease (CKD) and proteinuric ...