Sodium aescinate protects renal ischemia-reperfusion and pyroptosis through AKT/NLRP3 signaling pathway [0.03%]
山柰酚通过AKT/NLRP3信号通路保护肾缺血再灌注及吡啶苯并咪唑碱诱导的肾髓质微钙化导致的细胞焦亡
Liu Xin,Ning Kanghao,Li Jiacheng et al.
Liu Xin et al.
Renal ischemia-reperfusion injury (RIRI) is a common cause of acute renal injury. Studies have shown that sodium aescinate (SA) may serve as a potential therapeutic agent, although its exact mechanism remains unclear. This study first evalu...
Circ-0069561 as a novel diagnostic biomarker for progression of diabetic kidney disease [0.03%]
circ-0069561作为糖尿病肾脏疾病进展的新诊断生物标志物
Chaoyi Chen,Xinran Liu,Sai Zhu et al.
Chaoyi Chen et al.
Background: Circular RNAs (circRNAs) are non-coding RNAs that are key regulators of the initiation and progression of various human diseases. However, the role of circRNAs in diabetic kidney disease (DKD) remains unknown....
Friend or foe? The role of SIRT6 on macrophage polarized to M2 subtype in acute kidney injury to chronic kidney disease [0.03%]
朋友还是敌人？SIRT6在急性肾损伤演变为慢性肾病的M2型巨噬细胞极化中的作用
Xiaoqin Gao,Xingwei Liu,Zhaodi Han et al.
Xiaoqin Gao et al.
Acute kidney injury (AKI) substantially increases the risk of developing and worsening chronic kidney disease (CKD). The shift from AKI to CKD is a complex process that involves various cell types, with macrophages playing a key role in res...
Membranous nephropathy concurrent with renal amyloidosis: a six-patient report and literature review [0.03%]
与肾淀粉样变并发的膜性肾病-六例报告及文献复习
Zhe Li,Jing Liu,Shuhua Zhu et al.
Zhe Li et al.
The KDIGO 2021 guidelines suggest that individuals who test positive for serum anti-phospholipase A2 receptor (anti-PLA2R) antibodies may not require a renal biopsy to establish a diagnosis of membranous nephropathy (MN). However, it is imp...
Incidence of cytomegalovirus infection after kidney transplantation in the modern era of immunosuppression: the VINTAGE study [0.03%]
现代免疫抑制下的肾脏移植后巨细胞病毒的感染率：基于VINTAGE研究的结果
Sumi Hidaka,Kazunari Tanabe,Shuzo Kobayashi
Sumi Hidaka
Cytomegalovirus (CMV) infection is a frequent complication following kidney transplantation that affects transplant outcomes. This study aimed to (i) estimate the 12-month cumulative incidence of CMV antigenemia (AG) in adult kidney transpl...
miR-29a-3p/ Vegfa axis modulates high phosphate-induced vascular smooth muscle cell calcification [0.03%]
miR-29a-3p/Vegfa轴调节高磷诱导的血管平滑肌细胞钙化
Chen Fu,Qiaojing Liang,Lili Ma et al.
Chen Fu et al.
Vascular calcification (VC) is a major contributor to the progression of cardiovascular disease (CVD). The VC is characterized by arterial stiffness and impaired blood flow. This pathology is especially prevalent in chronic kidney disease (...
Chronic kidney Disease overall survival prediction model based on frailty index score: construction and validation using NHANES data [0.03%]
基于脆弱指数评分的慢性肾脏病整体生存预测模型的构建与验证——运用NHANES数据
Ting Li,Zaoqiang Lin,Zeyong Tang et al.
Ting Li et al.
Background: Frailty predicts poor outcomes in chronic kidney disease (CKD) patients. This study compared frailty's predictive power with other factors and aimed to develop a model for predicting overall survival (OS) in C...
Safflower injection against obesity-induced mice podocyte injury by improving insulin resistance through increasing renal INSR and eNOS expression [0.03%]
刺五加注射液通过改善胰岛素抵抗增加肾INSR和eNOS表达对抗肥胖小鼠足细胞损伤
Zhaodi Han,Xinyu Wang,Jing Liu et al.
Zhaodi Han et al.
Background: Podocyte injury is a common pathologic mechanism in obesity-related glomerulopathy (ORG). Safflower injection (SFI), scientifically extracted and refined from safflower, is used to treat diabetic kidney diseas...
The association between dietary live microbe intake and risk of chronic kidney disease among US adults: a cross-sectional survey from NHANES (2001-2018) [0.03%]
美国成年人中饮食摄入活菌与慢性肾脏病风险的关联：来自NHANES（2001-2018）的横断面调查结果
Xingzi Liu,Yang Shen,Kaiyi Zhu et al.
Xingzi Liu et al.
Background: Previous studies have suggested that gut dysbacteriosis may promote the onset of chronic kidney disease (CKD). However, the relationship between consumption of live microorganisms and CKD remains unclear. This...
Glucagon-like peptide-1 receptor agonists, inflammation, and kidney diseases: evidence from Mendelian randomization [0.03%]
基于孟德尔随机化的胰高血糖素样肽-1受体激动剂、炎症与肾脏疾病证据研究
Yu-Xuan Yao,Chen Tang,Feng-Lei Si et al.
Yu-Xuan Yao et al.
Objective: It has been proved that glucagon-like peptide-1 receptor (GLP1R) agonists have positive effects on renal outcomes in diabetic patients. However, it remains unknown whether GLP1R agonists could provide similar p...
Meta-Analysis
Renal failure. 2025 Dec;47(1):2478488. DOI:10.1080/0886022X.2025.2478488 2025