Validation of a renal staging system and its association with renal amyloid deposition burden in AL amyloidosis [0.03%]
AL型淀粉样变性肾分期系统的确证及其与肾脏淀粉样沉积负担的关系
Ying Yao,Shuang Wang,Dan-Yang Li et al.
Ying Yao et al.
Objectives: This study evaluates the relationship between renal amyloid deposition burden in kidney biopsy and a renal staging system based on proteinuria and estimated glomerular filtration rate (eGFR) in AL amyloidosis....
The combination of left ventricular ejection fraction and end-diastolic diameter and outcomes in peritoneal dialysis patients: a multicenter retrospective study [0.03%]
左心室射血分数和舒张末期直径与腹膜透析患者预后的关系：多中心回顾性研究
Jiayin You,Ning Su,Xiaoran Feng et al.
Jiayin You et al.
End-stage renal disease (ESRD) is often complicated by left ventricular dysfunction, which is associated with a poor prognosis. This study aims to investigate the association between baseline left ventricular ejection fraction (LVEF) plus l...
Multicenter Study
Renal failure. 2025 Dec;47(1):2497493. DOI:10.1080/0886022X.2025.2497493 2025
Shen Shuai II Recipe alleviates renal fibrosis in chronic kidney disease by improving of hypoxia and inhibition of TLR4/MyD88/NF-κB/NLRP3 pathway [0.03%]
Shen Shuai II方通过改善缺氧及抑制TLR4/MyD88/NF-κB/NLRP3信号通路治疗慢性肾脏病肾纤维化的作用研究
Yuan Zhou,Liang Zhou,Meng Wang et al.
Yuan Zhou et al.
Objectives: To investigate the anti-fibrotic mechanisms of Shen Shuai II Recipe (SSR) in chronic kidney disease (CKD), focusing on its modulation of hypoxia-associated inflammatory pathways and the TLR4/MyD88/NF-κB/NLRP3...
Dimethyl fumarate ameliorated pyroptosis in contrast-induced acute renal injury by regulating endoplasmic reticulum stress and JAK2-STAT3 pathway [0.03%]
富马酸二甲酯通过调节内质网应激和JAK2-STAT3信号通路改善对比剂诱导的急性肾损伤中的焦亡作用
Xiaoning An,Min Yin,Yilan Shen et al.
Xiaoning An et al.
Background: Inflammation and oxidative stress are important pathological processes of contrast-induced acute renal injury (CIAKI). This study explored whether DMF had therapeutic effects and investigated the underlying me...
Inhibition of caspase-1 by ginsenoside Rg1 ameliorates d-gal-induced renal aging and injury through suppression of oxidative stress and inflammation [0.03%]
人参皂苷Rg1通过抑制氧化应激和炎症抑制caspase-1改善d-半乳糖诱导的肾衰老和损伤
Tingting Guo,Ting Xie,Xuejun Chen et al.
Tingting Guo et al.
Background: The disruption of renal cell homeostasis caused by aging has attracted considerable attention. A traditional Chinese medicine, ginseng, is a potential drug for treating aging-related diseases. The study invest...
Immune-microbiota dysregulation in maintenance hemodialysis: a 16S rRNA sequencing-based analysis of gut flora and T cell profiles [0.03%]
维持性血液透析患者免疫-菌群失调的16S rRNA测序研究：肠道菌群与T细胞特征分析
Yan Lv,Xiuting Yang,Xiaowu Sun et al.
Yan Lv et al.
Background: Maintenance hemodialysis (MHD) patients frequently exhibit immune dysregulation and gut dysbiosis, both of which contribute to increased infection risk and adverse outcomes. However, the relationship between g...
Unveiling the role of oxidative stress in ANCA-associated glomerulonephritis through integrated machine learning and bioinformatics analyses [0.03%]
通过集成机器学习和生物信息学分析揭示氧化应激在ANCA相关性肾小球肾炎中的作用
Liyuan Xie,Xianying Qiu,Junya Jia et al.
Liyuan Xie et al.
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a systemic autoimmune disease often leading to rapidly progressive glomerulonephritis. Oxidative stress plays a critical role in the development and progression of A...
Prediction of peripheral blood lymphocyte subpopulations after renal transplantation [0.03%]
肾脏移植后外周血淋巴细胞亚群的预测
Bo Peng,Xuyu Xiang,Han Tian et al.
Bo Peng et al.
Immune monitoring is essential for maintaining immune homeostasis after renal transplantation (RT). Peripheral blood lymphocyte subpopulations (PBLSs) are widely used biomarkers for immune monitoring, yet there is no established standard re...
Integration of mitochondrial gene expression and immune landscape in acute kidney injury prediction [0.03%]
急性肾损伤预测中线粒体基因表达与免疫图谱的整合分析
Xiaoping Xia,Renyang Liu,Xiaohui Jiang
Xiaoping Xia
Background: Acute kidney injury (AKI) is a life-threatening condition with limited early biomarkers. Mitochondrial dysfunction is central to AKI pathophysiology, yet its potential for predicting AKI remains underexplored....
Non-steroidal mineralocorticoid receptor antagonist finerenone inhibits peritoneal fibrosis induced by high-glucose dialysate via regulating enhancer of zeste homolog 2 (EZH2) expression [0.03%]
非甾体类盐皮质激素受体拮抗剂芬瑞诺酮通过调节增强子-of-zeste同源物2(EZH2)的表达抑制高糖透析液诱导的小鼠腹膜纤维化
Dandan Chen,Jianqiang Shu,Xinyu Zhang et al.
Dandan Chen et al.
Finerenone, a novel high-selective aldosterone receptor antagonist, exhibits powerful anti-inflammatory and antifibrotic effects in previous researches. The aim of our study was to investigate of it on peritoneal fibrosis. In our current re...